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Q4UMS6

- RL2_RICFE

UniProt

Q4UMS6 - RL2_RICFE

Protein

50S ribosomal protein L2

Gene

rplB

Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 60 (01 Oct 2014)
      Sequence version 1 (05 Jul 2005)
      Previous versions | rss
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    Functioni

    One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.UniRule annotation

    GO - Molecular functioni

    1. rRNA binding Source: UniProtKB-HAMAP
    2. structural constituent of ribosome Source: InterPro
    3. transferase activity Source: InterPro

    GO - Biological processi

    1. translation Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Keywords - Ligandi

    RNA-binding, rRNA-binding

    Enzyme and pathway databases

    BioCyciRFEL315456:GKEK-291-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    50S ribosomal protein L2UniRule annotation
    Gene namesi
    Name:rplBUniRule annotation
    Ordered Locus Names:RF_0281
    OrganismiRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
    Taxonomic identifieri315456 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
    ProteomesiUP000008548: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. large ribosomal subunit Source: InterPro

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 27327350S ribosomal protein L2PRO_0000237235Add
    BLAST

    Interactioni

    Subunit structurei

    Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.UniRule annotation

    Protein-protein interaction databases

    STRINGi315456.RF_0281.

    Structurei

    3D structure databases

    ProteinModelPortaliQ4UMS6.
    SMRiQ4UMS6. Positions 8-272.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein L2P family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0090.
    HOGENOMiHOG000232982.
    KOiK02886.
    OMAiSAMNPID.
    OrthoDBiEOG6TR0J1.

    Family and domain databases

    Gene3Di2.30.30.30. 1 hit.
    2.40.50.140. 1 hit.
    4.10.950.10. 1 hit.
    HAMAPiMF_01320_B. Ribosomal_L2_B.
    InterProiIPR012340. NA-bd_OB-fold.
    IPR022666. Rbsml_prot_L2_RNA-bd_dom.
    IPR014722. Rib_L2_dom2.
    IPR002171. Ribosomal_L2.
    IPR005880. Ribosomal_L2_bac/org-type.
    IPR022669. Ribosomal_L2_C.
    IPR022671. Ribosomal_L2_CS.
    IPR014726. Ribosomal_L2_dom3.
    IPR008991. Translation_prot_SH3-like.
    [Graphical view]
    PANTHERiPTHR13691. PTHR13691. 1 hit.
    PTHR13691:SF5. PTHR13691:SF5. 1 hit.
    PfamiPF00181. Ribosomal_L2. 1 hit.
    PF03947. Ribosomal_L2_C. 1 hit.
    [Graphical view]
    PIRSFiPIRSF002158. Ribosomal_L2. 1 hit.
    SUPFAMiSSF50104. SSF50104. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsiTIGR01171. rplB_bact. 1 hit.
    PROSITEiPS00467. RIBOSOMAL_L2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q4UMS6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MALKNFNPIT PSLRELVQVD KTSLWKGRPL KSLTKGISKT GGRNNQGRIT    50
    SWHRGGGHKK LYRIIDFKRN KIDISAIVER IEYDPNRTAF IALIKYEDGE 100
    YSYILAPQKL SVGDRVISSQ DADIKIGNCL PLKFIPTGTT LHNVEMKVGK 150
    GGQIARSAGT SVDLVGKDSG YAQIKLRSGE FRLVPLDCKA TIGSISNPDQ 200
    KNINLGKAGR NRWLGWRPHV RGVAMNPVDH PHGGGEGKTS GGRHPVTPWG 250
    FPTKGKKTRK NKRTSKFIVK KRK 273
    Length:273
    Mass (Da):30,242
    Last modified:July 5, 2005 - v1
    Checksum:iFDF13E778648B777
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000053 Genomic DNA. Translation: AAY61132.1.
    RefSeqiYP_246297.1. NC_007109.1.

    Genome annotation databases

    EnsemblBacteriaiAAY61132; AAY61132; RF_0281.
    GeneIDi3400244.
    KEGGirfe:RF_0281.
    PATRICi17890974. VBIRicFel64634_0324.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000053 Genomic DNA. Translation: AAY61132.1 .
    RefSeqi YP_246297.1. NC_007109.1.

    3D structure databases

    ProteinModelPortali Q4UMS6.
    SMRi Q4UMS6. Positions 8-272.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 315456.RF_0281.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAY61132 ; AAY61132 ; RF_0281 .
    GeneIDi 3400244.
    KEGGi rfe:RF_0281.
    PATRICi 17890974. VBIRicFel64634_0324.

    Phylogenomic databases

    eggNOGi COG0090.
    HOGENOMi HOG000232982.
    KOi K02886.
    OMAi SAMNPID.
    OrthoDBi EOG6TR0J1.

    Enzyme and pathway databases

    BioCyci RFEL315456:GKEK-291-MONOMER.

    Family and domain databases

    Gene3Di 2.30.30.30. 1 hit.
    2.40.50.140. 1 hit.
    4.10.950.10. 1 hit.
    HAMAPi MF_01320_B. Ribosomal_L2_B.
    InterProi IPR012340. NA-bd_OB-fold.
    IPR022666. Rbsml_prot_L2_RNA-bd_dom.
    IPR014722. Rib_L2_dom2.
    IPR002171. Ribosomal_L2.
    IPR005880. Ribosomal_L2_bac/org-type.
    IPR022669. Ribosomal_L2_C.
    IPR022671. Ribosomal_L2_CS.
    IPR014726. Ribosomal_L2_dom3.
    IPR008991. Translation_prot_SH3-like.
    [Graphical view ]
    PANTHERi PTHR13691. PTHR13691. 1 hit.
    PTHR13691:SF5. PTHR13691:SF5. 1 hit.
    Pfami PF00181. Ribosomal_L2. 1 hit.
    PF03947. Ribosomal_L2_C. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF002158. Ribosomal_L2. 1 hit.
    SUPFAMi SSF50104. SSF50104. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsi TIGR01171. rplB_bact. 1 hit.
    PROSITEi PS00467. RIBOSOMAL_L2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
      Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
      PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC VR-1525 / URRWXCal2.

    Entry informationi

    Entry nameiRL2_RICFE
    AccessioniPrimary (citable) accession number: Q4UMS6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 30, 2006
    Last sequence update: July 5, 2005
    Last modified: October 1, 2014
    This is version 60 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Ribosomal proteins
      Ribosomal proteins families and list of entries
    2. Rickettsia felis (Rickettsia azadi)
      Rickettsia felis (strain URRWXCal2): entries and gene names
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3