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Q4UMS6 (RL2_RICFE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
50S ribosomal protein L2
Gene names
Name:rplB
Ordered Locus Names:RF_0281
OrganismRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) [Complete proteome] [HAMAP]
Taxonomic identifier315456 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group

Protein attributes

Sequence length273 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome By similarity. HAMAP-Rule MF_01320

Subunit structure

Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome By similarity.

Sequence similarities

Belongs to the ribosomal protein L2P family.

Ontologies

Keywords
   LigandRNA-binding
rRNA-binding
   Molecular functionRibonucleoprotein
Ribosomal protein
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtranslation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentlarge ribosomal subunit

Inferred from electronic annotation. Source: InterPro

   Molecular_functionrRNA binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

structural constituent of ribosome

Inferred from electronic annotation. Source: InterPro

transferase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 27327350S ribosomal protein L2 HAMAP-Rule MF_01320
PRO_0000237235

Sequences

Sequence LengthMass (Da)Tools
Q4UMS6 [UniParc].

Last modified July 5, 2005. Version 1.
Checksum: FDF13E778648B777

FASTA27330,242
        10         20         30         40         50         60 
MALKNFNPIT PSLRELVQVD KTSLWKGRPL KSLTKGISKT GGRNNQGRIT SWHRGGGHKK 

        70         80         90        100        110        120 
LYRIIDFKRN KIDISAIVER IEYDPNRTAF IALIKYEDGE YSYILAPQKL SVGDRVISSQ 

       130        140        150        160        170        180 
DADIKIGNCL PLKFIPTGTT LHNVEMKVGK GGQIARSAGT SVDLVGKDSG YAQIKLRSGE 

       190        200        210        220        230        240 
FRLVPLDCKA TIGSISNPDQ KNINLGKAGR NRWLGWRPHV RGVAMNPVDH PHGGGEGKTS 

       250        260        270 
GGRHPVTPWG FPTKGKKTRK NKRTSKFIVK KRK 

« Hide

References

[1]"The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-1525 / URRWXCal2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000053 Genomic DNA. Translation: AAY61132.1.
RefSeqYP_246297.1. NC_007109.1.

3D structure databases

ProteinModelPortalQ4UMS6.
SMRQ4UMS6. Positions 8-272.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING315456.RF_0281.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAY61132; AAY61132; RF_0281.
GeneID3400244.
KEGGrfe:RF_0281.
PATRIC17890974. VBIRicFel64634_0324.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0090.
HOGENOMHOG000232982.
KOK02886.
OMASAMNPID.
OrthoDBEOG6TR0J1.

Enzyme and pathway databases

BioCycRFEL315456:GKEK-291-MONOMER.

Family and domain databases

Gene3D2.30.30.30. 1 hit.
2.40.50.140. 1 hit.
4.10.950.10. 1 hit.
HAMAPMF_01320_B. Ribosomal_L2_B.
InterProIPR012340. NA-bd_OB-fold.
IPR022666. Rbsml_prot_L2_RNA-bd_dom.
IPR014722. Rib_L2_dom2.
IPR002171. Ribosomal_L2.
IPR005880. Ribosomal_L2_bac/org-type.
IPR022669. Ribosomal_L2_C.
IPR022671. Ribosomal_L2_CS.
IPR014726. Ribosomal_L2_dom3.
IPR008991. Translation_prot_SH3-like.
[Graphical view]
PANTHERPTHR13691. PTHR13691. 1 hit.
PTHR13691:SF5. PTHR13691:SF5. 1 hit.
PfamPF00181. Ribosomal_L2. 1 hit.
PF03947. Ribosomal_L2_C. 1 hit.
[Graphical view]
PIRSFPIRSF002158. Ribosomal_L2. 1 hit.
SUPFAMSSF50104. SSF50104. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsTIGR01171. rplB_bact. 1 hit.
PROSITEPS00467. RIBOSOMAL_L2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRL2_RICFE
AccessionPrimary (citable) accession number: Q4UMS6
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: July 5, 2005
Last modified: May 14, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia felis (Rickettsia azadi)

Rickettsia felis (strain URRWXCal2): entries and gene names

Ribosomal proteins

Ribosomal proteins families and list of entries