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Q4UMR7 (RL5_RICFE) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
50S ribosomal protein L5
Gene names
Name:rplE
Ordered Locus Names:RF_0290
OrganismRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) [Complete proteome] [HAMAP]
Taxonomic identifier315456 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group

Protein attributes

Sequence length179 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs By similarity. HAMAP-Rule MF_01333

Subunit structure

Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome By similarity.

Sequence similarities

Belongs to the ribosomal protein L5P family.

Ontologies

Keywords
   LigandRNA-binding
rRNA-binding
tRNA-binding
   Molecular functionRibonucleoprotein
Ribosomal protein
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtranslation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentribosome

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionrRNA binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

structural constituent of ribosome

Inferred from electronic annotation. Source: InterPro

tRNA binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 17917950S ribosomal protein L5 HAMAP-Rule MF_01333
PRO_0000243056

Sequences

Sequence LengthMass (Da)Tools
Q4UMR7 [UniParc].

Last modified July 5, 2005. Version 1.
Checksum: 75C4A25F45EB8233

FASTA17920,629
        10         20         30         40         50         60 
MLRFKELYQQ KIIENLQKEF SYKSKHEIPQ IKKIVINMGV GEAIADSKVI NNAVNDLTLI 

        70         80         90        100        110        120 
SGQKPVVTLA RKSIATFKLR ESMKIGCKVT LRKDRMYDFL ERLVIVALPR VKEFRGFSYK 

       130        140        150        160        170 
SFDGKGNFTF GLKEQIVFPE INYDKIDTIR GMDITIVTSA KTDKESKFLL SGFNLPFYN 

« Hide

References

[1]"The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-1525 / URRWXCal2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000053 Genomic DNA. Translation: AAY61141.1.
RefSeqYP_246306.1. NC_007109.1.

3D structure databases

ProteinModelPortalQ4UMR7.
SMRQ4UMR7. Positions 1-178.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING315456.RF_0290.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAY61141; AAY61141; RF_0290.
GeneID3400253.
KEGGrfe:RF_0290.
PATRIC17890992. VBIRicFel64634_0333.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0094.
HOGENOMHOG000231311.
KOK02931.
OMAGMPIGAH.
OrthoDBEOG6M9F1R.
ProtClustDBPRK00010.

Enzyme and pathway databases

BioCycRFEL315456:GKEK-300-MONOMER.

Family and domain databases

Gene3D3.30.1440.10. 1 hit.
HAMAPMF_01333_B. Ribosomal_L5_B.
InterProIPR002132. Ribosomal_L5.
IPR020930. Ribosomal_L5_bac-type.
IPR020929. Ribosomal_L5_CS.
IPR022803. Ribosomal_L5_domain.
[Graphical view]
PANTHERPTHR11994. PTHR11994. 1 hit.
PfamPF00281. Ribosomal_L5. 1 hit.
PF00673. Ribosomal_L5_C. 1 hit.
[Graphical view]
PIRSFPIRSF002161. Ribosomal_L5. 1 hit.
SUPFAMSSF55282. SSF55282. 1 hit.
PROSITEPS00358. RIBOSOMAL_L5. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRL5_RICFE
AccessionPrimary (citable) accession number: Q4UMR7
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: July 5, 2005
Last modified: February 19, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia felis (Rickettsia azadi)

Rickettsia felis (strain URRWXCal2): entries and gene names

Ribosomal proteins

Ribosomal proteins families and list of entries