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Q4UMR7

- RL5_RICFE

UniProt

Q4UMR7 - RL5_RICFE

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Protein

50S ribosomal protein L5

Gene
rplE, RF_0290
Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs By similarity.UniRule annotation

GO - Molecular functioni

  1. rRNA binding Source: UniProtKB-HAMAP
  2. structural constituent of ribosome Source: InterPro
  3. tRNA binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. translation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding, tRNA-binding

Enzyme and pathway databases

BioCyciRFEL315456:GKEK-300-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L5
Gene namesi
Name:rplE
Ordered Locus Names:RF_0290
OrganismiRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Taxonomic identifieri315456 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
ProteomesiUP000008548: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. ribosome Source: UniProtKB-KW
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 17917950S ribosomal protein L5UniRule annotationPRO_0000243056Add
BLAST

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome By similarity.

Protein-protein interaction databases

STRINGi315456.RF_0290.

Structurei

3D structure databases

ProteinModelPortaliQ4UMR7.
SMRiQ4UMR7. Positions 1-178.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0094.
HOGENOMiHOG000231311.
KOiK02931.
OMAiTEQLIFP.
OrthoDBiEOG6M9F1R.

Family and domain databases

Gene3Di3.30.1440.10. 1 hit.
HAMAPiMF_01333_B. Ribosomal_L5_B.
InterProiIPR002132. Ribosomal_L5.
IPR020930. Ribosomal_L5_bac-type.
IPR020929. Ribosomal_L5_CS.
IPR022803. Ribosomal_L5_domain.
[Graphical view]
PANTHERiPTHR11994. PTHR11994. 1 hit.
PfamiPF00281. Ribosomal_L5. 1 hit.
PF00673. Ribosomal_L5_C. 1 hit.
[Graphical view]
PIRSFiPIRSF002161. Ribosomal_L5. 1 hit.
SUPFAMiSSF55282. SSF55282. 1 hit.
PROSITEiPS00358. RIBOSOMAL_L5. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4UMR7-1 [UniParc]FASTAAdd to Basket

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MLRFKELYQQ KIIENLQKEF SYKSKHEIPQ IKKIVINMGV GEAIADSKVI    50
NNAVNDLTLI SGQKPVVTLA RKSIATFKLR ESMKIGCKVT LRKDRMYDFL 100
ERLVIVALPR VKEFRGFSYK SFDGKGNFTF GLKEQIVFPE INYDKIDTIR 150
GMDITIVTSA KTDKESKFLL SGFNLPFYN 179
Length:179
Mass (Da):20,629
Last modified:July 5, 2005 - v1
Checksum:i75C4A25F45EB8233
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000053 Genomic DNA. Translation: AAY61141.1.
RefSeqiWP_011270639.1. NC_007109.1.
YP_246306.1. NC_007109.1.

Genome annotation databases

EnsemblBacteriaiAAY61141; AAY61141; RF_0290.
GeneIDi3400253.
KEGGirfe:RF_0290.
PATRICi17890992. VBIRicFel64634_0333.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000053 Genomic DNA. Translation: AAY61141.1 .
RefSeqi WP_011270639.1. NC_007109.1.
YP_246306.1. NC_007109.1.

3D structure databases

ProteinModelPortali Q4UMR7.
SMRi Q4UMR7. Positions 1-178.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 315456.RF_0290.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAY61141 ; AAY61141 ; RF_0290 .
GeneIDi 3400253.
KEGGi rfe:RF_0290.
PATRICi 17890992. VBIRicFel64634_0333.

Phylogenomic databases

eggNOGi COG0094.
HOGENOMi HOG000231311.
KOi K02931.
OMAi TEQLIFP.
OrthoDBi EOG6M9F1R.

Enzyme and pathway databases

BioCyci RFEL315456:GKEK-300-MONOMER.

Family and domain databases

Gene3Di 3.30.1440.10. 1 hit.
HAMAPi MF_01333_B. Ribosomal_L5_B.
InterProi IPR002132. Ribosomal_L5.
IPR020930. Ribosomal_L5_bac-type.
IPR020929. Ribosomal_L5_CS.
IPR022803. Ribosomal_L5_domain.
[Graphical view ]
PANTHERi PTHR11994. PTHR11994. 1 hit.
Pfami PF00281. Ribosomal_L5. 1 hit.
PF00673. Ribosomal_L5_C. 1 hit.
[Graphical view ]
PIRSFi PIRSF002161. Ribosomal_L5. 1 hit.
SUPFAMi SSF55282. SSF55282. 1 hit.
PROSITEi PS00358. RIBOSOMAL_L5. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
    Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
    PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-1525 / URRWXCal2.

Entry informationi

Entry nameiRL5_RICFE
AccessioniPrimary (citable) accession number: Q4UMR7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: July 5, 2005
Last modified: September 3, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. Rickettsia felis (Rickettsia azadi)
    Rickettsia felis (strain URRWXCal2): entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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