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Q4UMR7

- RL5_RICFE

UniProt

Q4UMR7 - RL5_RICFE

Protein

50S ribosomal protein L5

Gene

rplE

Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 57 (01 Oct 2014)
      Sequence version 1 (05 Jul 2005)
      Previous versions | rss
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    Functioni

    This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.UniRule annotation

    GO - Molecular functioni

    1. rRNA binding Source: UniProtKB-HAMAP
    2. structural constituent of ribosome Source: InterPro
    3. tRNA binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. translation Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Keywords - Ligandi

    RNA-binding, rRNA-binding, tRNA-binding

    Enzyme and pathway databases

    BioCyciRFEL315456:GKEK-300-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    50S ribosomal protein L5UniRule annotation
    Gene namesi
    Name:rplEUniRule annotation
    Ordered Locus Names:RF_0290
    OrganismiRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
    Taxonomic identifieri315456 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
    ProteomesiUP000008548: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. ribosome Source: UniProtKB-KW

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 17917950S ribosomal protein L5PRO_0000243056Add
    BLAST

    Interactioni

    Subunit structurei

    Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.UniRule annotation

    Protein-protein interaction databases

    STRINGi315456.RF_0290.

    Structurei

    3D structure databases

    ProteinModelPortaliQ4UMR7.
    SMRiQ4UMR7. Positions 1-178.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein L5P family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0094.
    HOGENOMiHOG000231311.
    KOiK02931.
    OMAiTEQLIFP.
    OrthoDBiEOG6M9F1R.

    Family and domain databases

    Gene3Di3.30.1440.10. 1 hit.
    HAMAPiMF_01333_B. Ribosomal_L5_B.
    InterProiIPR002132. Ribosomal_L5.
    IPR020930. Ribosomal_L5_bac-type.
    IPR020929. Ribosomal_L5_CS.
    IPR022803. Ribosomal_L5_domain.
    [Graphical view]
    PANTHERiPTHR11994. PTHR11994. 1 hit.
    PfamiPF00281. Ribosomal_L5. 1 hit.
    PF00673. Ribosomal_L5_C. 1 hit.
    [Graphical view]
    PIRSFiPIRSF002161. Ribosomal_L5. 1 hit.
    SUPFAMiSSF55282. SSF55282. 1 hit.
    PROSITEiPS00358. RIBOSOMAL_L5. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q4UMR7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLRFKELYQQ KIIENLQKEF SYKSKHEIPQ IKKIVINMGV GEAIADSKVI    50
    NNAVNDLTLI SGQKPVVTLA RKSIATFKLR ESMKIGCKVT LRKDRMYDFL 100
    ERLVIVALPR VKEFRGFSYK SFDGKGNFTF GLKEQIVFPE INYDKIDTIR 150
    GMDITIVTSA KTDKESKFLL SGFNLPFYN 179
    Length:179
    Mass (Da):20,629
    Last modified:July 5, 2005 - v1
    Checksum:i75C4A25F45EB8233
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000053 Genomic DNA. Translation: AAY61141.1.
    RefSeqiWP_011270639.1. NC_007109.1.
    YP_246306.1. NC_007109.1.

    Genome annotation databases

    EnsemblBacteriaiAAY61141; AAY61141; RF_0290.
    GeneIDi3400253.
    KEGGirfe:RF_0290.
    PATRICi17890992. VBIRicFel64634_0333.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000053 Genomic DNA. Translation: AAY61141.1 .
    RefSeqi WP_011270639.1. NC_007109.1.
    YP_246306.1. NC_007109.1.

    3D structure databases

    ProteinModelPortali Q4UMR7.
    SMRi Q4UMR7. Positions 1-178.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 315456.RF_0290.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAY61141 ; AAY61141 ; RF_0290 .
    GeneIDi 3400253.
    KEGGi rfe:RF_0290.
    PATRICi 17890992. VBIRicFel64634_0333.

    Phylogenomic databases

    eggNOGi COG0094.
    HOGENOMi HOG000231311.
    KOi K02931.
    OMAi TEQLIFP.
    OrthoDBi EOG6M9F1R.

    Enzyme and pathway databases

    BioCyci RFEL315456:GKEK-300-MONOMER.

    Family and domain databases

    Gene3Di 3.30.1440.10. 1 hit.
    HAMAPi MF_01333_B. Ribosomal_L5_B.
    InterProi IPR002132. Ribosomal_L5.
    IPR020930. Ribosomal_L5_bac-type.
    IPR020929. Ribosomal_L5_CS.
    IPR022803. Ribosomal_L5_domain.
    [Graphical view ]
    PANTHERi PTHR11994. PTHR11994. 1 hit.
    Pfami PF00281. Ribosomal_L5. 1 hit.
    PF00673. Ribosomal_L5_C. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF002161. Ribosomal_L5. 1 hit.
    SUPFAMi SSF55282. SSF55282. 1 hit.
    PROSITEi PS00358. RIBOSOMAL_L5. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
      Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
      PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC VR-1525 / URRWXCal2.

    Entry informationi

    Entry nameiRL5_RICFE
    AccessioniPrimary (citable) accession number: Q4UMR7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 27, 2006
    Last sequence update: July 5, 2005
    Last modified: October 1, 2014
    This is version 57 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Ribosomal proteins
      Ribosomal proteins families and list of entries
    2. Rickettsia felis (Rickettsia azadi)
      Rickettsia felis (strain URRWXCal2): entries and gene names
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3