Q4UMR4 (RL6_RICFE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L6

Gene names

Name:	rplF
Ordered Locus Names:	RF_0293

Organism

Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) [Complete proteome] [HAMAP]

Taxonomic identifier

315456 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group › Rickettsia felis

Protein attributes

Sequence length	177 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center By similarity. HAMAP-Rule MF_01365
Subunit structure	Part of the 50S ribosomal subunit By similarity.
Sequence similarities	Belongs to the ribosomal protein L6P family.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	translation Inferred from electronic annotation. Source: HAMAP
Cellular_component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	rRNA binding Inferred from electronic annotation. Source: HAMAP structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 177	177	50S ribosomal protein L6 HAMAP-Rule MF_01365		PRO_0000265287

Sequences

	Sequence		Length	Mass (Da)
	Q4UMR4 [UniParc]. Last modified July 5, 2005. Version 1. Checksum: C321FC9D3F760B9C	FASTA	177	19,578
	10 20 30 40 50 60 MSRVGKLPIT IPEGVKVGLN DLEVKISGPK GELSKTFKGN IAISLEENKL LVKPLAANKN 70 80 90 100 110 120 ARAMWGTARS IISNMVTGVK EGFKLKLEIN GVGYRAMVKG KYLNLMLAKS HNTKIEIPSD 130 140 150 160 170 IKIEVPKQNI IILEGTDKEK LGQFASIIIK QRPPEPYKGK GIKFENQFIP RKEGKKN

References

[1]

"The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite." Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D. PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-1525 / URRWXCal2.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000053 Genomic DNA. Translation: AAY61144.1.
RefSeq	YP_246309.1. NC_007109.1.
3D structure databases
HSSP	HSSP built from PDB template 1C04 based on UniProtKB P02391.
ProteinModelPortal	Q4UMR4.
ModBase	Search...
Protein-protein interaction databases
STRING	315456.RF_0293.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAY61144; AAY61144; RF_0293.
GeneID	3400256.
KEGG	rfe:RF_0293.
PATRIC	17890998. VBIRicFel64634_0336.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0097.
HOGENOM	HOG000039903.
KO	K02933.
OMA	INNMVVG.
ProtClustDB	PRK05498.
Family and domain databases
Gene3D	3.90.930.12. 2 hits.
HAMAP	MF_01365_B. Ribosomal_L6_B.
InterPro	IPR000702. Ribosomal_L6. IPR020040. Ribosomal_L6_a/b-dom. IPR019906. Ribosomal_L6_bac-type. IPR002358. Ribosomal_L6_CS. [Graphical view]
PANTHER	PTHR11655. PTHR11655. 1 hit. PTHR11655:SF6. PTHR11655:SF6. 1 hit.
Pfam	PF00347. Ribosomal_L6. 2 hits. [Graphical view]
PIRSF	PIRSF002162. Ribosomal_L6. 1 hit.
PRINTS	PR00059. RIBOSOMALL6.
SUPFAM	SSF56053. Ribosomal_L6. 2 hits.
TIGRFAMs	TIGR03654. L6_bact. 1 hit.
PROSITE	PS00525. RIBOSOMAL_L6_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RL6_RICFE

Accession

Primary (citable) accession number: Q4UMR4

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 12, 2006
Last sequence update:	July 5, 2005
Last modified:	May 1, 2013
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program