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Q4UMK4

- PTH_RICFE

UniProt

Q4UMK4 - PTH_RICFE

Protein

Peptidyl-tRNA hydrolase

Gene

pth

Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 59 (01 Oct 2014)
      Sequence version 1 (05 Jul 2005)
      Previous versions | rss
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    Functioni

    The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.UniRule annotation

    Catalytic activityi

    N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.UniRule annotation

    GO - Molecular functioni

    1. aminoacyl-tRNA hydrolase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Hydrolase

    Enzyme and pathway databases

    BioCyciRFEL315456:GKEK-366-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Peptidyl-tRNA hydrolaseUniRule annotation (EC:3.1.1.29UniRule annotation)
    Short name:
    PTHUniRule annotation
    Gene namesi
    Name:pthUniRule annotation
    Ordered Locus Names:RF_0353
    OrganismiRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
    Taxonomic identifieri315456 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
    ProteomesiUP000008548: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 185185Peptidyl-tRNA hydrolasePRO_0000264097Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi315456.RF_0353.

    Structurei

    3D structure databases

    ProteinModelPortaliQ4UMK4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PTH family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0193.
    HOGENOMiHOG000004797.
    KOiK01056.
    OMAiAMHRLHS.
    OrthoDBiEOG6C5RTR.

    Family and domain databases

    Gene3Di3.40.50.1470. 1 hit.
    HAMAPiMF_00083. Pept_tRNA_hydro_bact.
    InterProiIPR001328. Pept_tRNA_hydro.
    IPR018171. Pept_tRNA_hydro_CS.
    [Graphical view]
    PANTHERiPTHR17224. PTHR17224. 1 hit.
    PfamiPF01195. Pept_tRNA_hydro. 1 hit.
    [Graphical view]
    SUPFAMiSSF53178. SSF53178. 1 hit.
    TIGRFAMsiTIGR00447. pth. 1 hit.
    PROSITEiPS01195. PEPT_TRNA_HYDROL_1. 1 hit.
    PS01196. PEPT_TRNA_HYDROL_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q4UMK4-1 [UniParc]FASTAAdd to Basket

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    MILVIGLGNP GKEYQYTRHN IGFIAIEKIA NQYNSSFSIK KKFNCEIAET    50
    ISDGQKIIFI KPTTYMNLSG KSVISVKTYY NIQSAKIFVI HDDIDLETGR 100
    IKFKTGGGNG GHNGLKSIDG VIGNNYNRIR VGVGRPQNNQ DVADYVLNNF 150
    LKSEYETALQ AIDRIANNFD LILENKLEEF KNKIV 185
    Length:185
    Mass (Da):20,785
    Last modified:July 5, 2005 - v1
    Checksum:iBE03635B6D526723
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000053 Genomic DNA. Translation: AAY61204.1.
    RefSeqiWP_011270692.1. NC_007109.1.
    YP_246369.1. NC_007109.1.

    Genome annotation databases

    EnsemblBacteriaiAAY61204; AAY61204; RF_0353.
    GeneIDi3400319.
    KEGGirfe:RF_0353.
    PATRICi17891156. VBIRicFel64634_0412.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000053 Genomic DNA. Translation: AAY61204.1 .
    RefSeqi WP_011270692.1. NC_007109.1.
    YP_246369.1. NC_007109.1.

    3D structure databases

    ProteinModelPortali Q4UMK4.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 315456.RF_0353.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAY61204 ; AAY61204 ; RF_0353 .
    GeneIDi 3400319.
    KEGGi rfe:RF_0353.
    PATRICi 17891156. VBIRicFel64634_0412.

    Phylogenomic databases

    eggNOGi COG0193.
    HOGENOMi HOG000004797.
    KOi K01056.
    OMAi AMHRLHS.
    OrthoDBi EOG6C5RTR.

    Enzyme and pathway databases

    BioCyci RFEL315456:GKEK-366-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.1470. 1 hit.
    HAMAPi MF_00083. Pept_tRNA_hydro_bact.
    InterProi IPR001328. Pept_tRNA_hydro.
    IPR018171. Pept_tRNA_hydro_CS.
    [Graphical view ]
    PANTHERi PTHR17224. PTHR17224. 1 hit.
    Pfami PF01195. Pept_tRNA_hydro. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53178. SSF53178. 1 hit.
    TIGRFAMsi TIGR00447. pth. 1 hit.
    PROSITEi PS01195. PEPT_TRNA_HYDROL_1. 1 hit.
    PS01196. PEPT_TRNA_HYDROL_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
      Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
      PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC VR-1525 / URRWXCal2.

    Entry informationi

    Entry nameiPTH_RICFE
    AccessioniPrimary (citable) accession number: Q4UMK4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 12, 2006
    Last sequence update: July 5, 2005
    Last modified: October 1, 2014
    This is version 59 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Rickettsia felis (Rickettsia azadi)
      Rickettsia felis (strain URRWXCal2): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3