Reviewed, UniProtKB/Swiss-Prot Q4UM33 (CAPD_RICFE)

Names and origin

Protein names

Recommended name:
    UDP-glucose 4-epimerase
    EC=5.1.3.2
Alternative name(s):
    UDP-galactose 4-epimerase
    Galactowaldenase

Gene names

Name:	capD
Ordered Locus Names:	RF_0539

Organism

Rickettsia felis (Rickettsia azadi) [Complete proteome] [HAMAP]

Taxonomic identifier

42862 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group

Protein attributes

Sequence length	341 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Epimerizes UDP-galactose to UDP-glucose By similarity.
Catalytic activity	UDP-glucose = UDP-galactose.
Sequence similarities	Belongs to the polysaccharide synthase family.

Ontologies

Keywords
Biological process	Lipopolysaccharide biosynthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipopolysaccharide biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	UDP-glucose 4-epimerase activity Inferred from electronic annotation. Source: EC binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 341	341	UDP-glucose 4-epimerase		PRO_0000314604

Sequences

	Sequence		Length	Mass (Da)
	Q4UM33-1 [UniParc]. Last modified July 5, 2005. Version 1. Checksum: 39BB0D5528F5D2E1	FASTA	341	38,362
	10 20 30 40 50 60 MFVDKTLMIT GGTGSFGNAV LSRFLKSDIT NDIKEIRIFS RDEKKQEDMR IALNNPKLKF 70 80 90 100 110 120 YIGDVRNYKS IDEAMHGVDY VFHAAALKQV PTCEFYPMEA INTNVLGAEN VLSAAINNKV 130 140 150 160 170 180 AKVIVLSTDK AVYPINAMGL SKALMEKLAV AKARMRSQGE TVLCVTRYGN VMASRGSVIP 190 200 210 220 230 240 LFINQIKQDK DLTITEPSMT RFLMSLVDSV DLVLYAFEHG RQGDIFVQKS PASTIEVLAK 250 260 270 280 290 300 ALQEIFGSKN ELRFIGTRHG EKHYESLVSS EEMAKADDLG GYYRIPMDGR DLNYAKYFVE 310 320 330 340 GEKKVALLED YNSHNTKRLN LEEVKELLLN LDYVQEELKN A

References

[1]

"The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite." Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D. PLoS Biol. 3:1-12(2005) [PubMed: 15984913] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-1525 / URRWXCal2.

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000053 Genomic DNA. Translation: AAY61390.1.
RefSeq	YP_246555.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3401201.
GenomeReviews	Gene locus RF_0539 in contig CP000053_GR.
KEGG	rfe:RF_0539.
NMPDR	fig|315456.3.peg.373.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q4UM33.
OMA	Q4UM33. GDIFVQK.
Enzyme and pathway databases
BioCyc	RFEL315456:RF_0539-MON.
BRENDA	5.1.3.2. 297363.
Family and domain databases
InterPro	IPR016040. NAD(P)-bd_dom. IPR003869. Polysac_CapD-like. IPR013692. Polysac_syn_C. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
PANTHER	PTHR10366:SF23. Polysac_CapD. 1 hit.
Pfam	PF08485. Polysacc_syn_2C. 1 hit. PF02719. Polysacc_synt_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CAPD_RICFE

Accession

Primary (citable) accession number: Q4UM33

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	July 5, 2005
Last modified:	June 16, 2009
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)