Q4UM33 (CAPD_RICFE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
UDP-glucose 4-epimerase
EC=5.1.3.2

Alternative name(s):
Galactowaldenase
UDP-galactose 4-epimerase

Gene names

Name:	capD
Ordered Locus Names:	RF_0539

Organism

Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) [Complete proteome] [HAMAP]

Taxonomic identifier

315456 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group

Protein attributes

Sequence length	341 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Epimerizes UDP-galactose to UDP-glucose By similarity.
Catalytic activity	UDP-glucose = UDP-galactose.
Sequence similarities	Belongs to the polysaccharide synthase family.

Ontologies

Keywords
Biological process	Lipopolysaccharide biosynthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipopolysaccharide biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	UDP-glucose 4-epimerase activity Inferred from electronic annotation. Source: EC nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 341	341	UDP-glucose 4-epimerase		PRO_0000314604

Sequences

	Sequence		Length	Mass (Da)
	Q4UM33 [UniParc]. Last modified July 5, 2005. Version 1. Checksum: 39BB0D5528F5D2E1	FASTA	341	38,362
	10 20 30 40 50 60 MFVDKTLMIT GGTGSFGNAV LSRFLKSDIT NDIKEIRIFS RDEKKQEDMR IALNNPKLKF 70 80 90 100 110 120 YIGDVRNYKS IDEAMHGVDY VFHAAALKQV PTCEFYPMEA INTNVLGAEN VLSAAINNKV 130 140 150 160 170 180 AKVIVLSTDK AVYPINAMGL SKALMEKLAV AKARMRSQGE TVLCVTRYGN VMASRGSVIP 190 200 210 220 230 240 LFINQIKQDK DLTITEPSMT RFLMSLVDSV DLVLYAFEHG RQGDIFVQKS PASTIEVLAK 250 260 270 280 290 300 ALQEIFGSKN ELRFIGTRHG EKHYESLVSS EEMAKADDLG GYYRIPMDGR DLNYAKYFVE 310 320 330 340 GEKKVALLED YNSHNTKRLN LEEVKELLLN LDYVQEELKN A

References

[1]

"The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite." Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D. PLoS Biol. 3:1-12(2005) [PubMed: 15984913] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-1525 / URRWXCal2.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000053 Genomic DNA. Translation: AAY61390.1.
RefSeq	YP_246555.1. NC_007109.1.
3D structure databases
HSSP	HSSP built from PDB template 2GN8 based on UniProtKB O25511.
ProteinModelPortal	Q4UM33.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3401201.
GenomeReviews	Gene locus RF_0539 in contig CP000053_GR.
KEGG	rfe:RF_0539.
NMPDR	fig|315456.3.peg.373.
PATRIC	17891608. VBIRicFel64634_0637.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG429349.
OMA	LNYAKYF.
ProtClustDB	CLSK870330.
Enzyme and pathway databases
BioCyc	RFEL315456:RF_0539-MONOMER.
Family and domain databases
InterPro	IPR016040. NAD(P)-bd_dom. IPR003869. Polysac_CapD-like. IPR013692. Polysac_syn_C. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
Pfam	PF08485. Polysacc_syn_2C. 1 hit. PF02719. Polysacc_synt_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CAPD_RICFE

Accession

Primary (citable) accession number: Q4UM33

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	July 5, 2005
Last modified:	January 25, 2012
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program