Q4UM12 (3MGH_RICFE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative 3-methyladenine DNA glycosylase
EC=3.2.2.-

Gene names

Ordered Locus Names:

RF_0560

Organism

Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) [Complete proteome] [HAMAP]

Taxonomic identifier

315456 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group › Rickettsia felis

Protein attributes

Sequence length	177 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the DNA glycosylase MPG family.

Ontologies

Keywords
Biological process	DNA damage DNA repair
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	base-excision repair Inferred from electronic annotation. Source: InterPro
Molecular_function	DNA binding Inferred from electronic annotation. Source: InterPro alkylbase DNA N-glycosylase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 177	177	Putative 3-methyladenine DNA glycosylase HAMAP-Rule MF_00527		PRO_0000265055

Sequences

	Sequence		Length	Mass (Da)
	Q4UM12 [UniParc]. Last modified July 5, 2005. Version 1. Checksum: E2D06F077B35F3C8	FASTA	177	19,932
	10 20 30 40 50 60 MNKLILLPRE FFARDTNLVS TELIGKVLYF QGKTAIITET ESYIGQDDPA CHAARGRTKR 70 80 90 100 110 120 TDIMFGPAGF SYVYLIYGMY YCLNFVTETE GFPAATLIRG VHVISPENLY LNGPGKLCKY 130 140 150 160 170 LGINISHNKC DLINNNEFFV SDIGLKLPYS TTTRIGITKG TDKLWRYVVT DIIRLPA

References

[1]

"The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite." Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D. PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-1525 / URRWXCal2.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000053 Genomic DNA. Translation: AAY61411.1.
RefSeq	YP_246576.1. NC_007109.1.
3D structure databases
HSSP	HSSP built from PDB template 1F4R based on UniProtKB P29372.
ProteinModelPortal	Q4UM12.
ModBase	Search...
Protein-protein interaction databases
STRING	315456.RF_0560.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAY61411; AAY61411; RF_0560.
GeneID	3400339.
KEGG	rfe:RF_0560.
PATRIC	17891669. VBIRicFel64634_0667.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2094.
HOGENOM	HOG000224224.
KO	K03652.
OMA	CTPRIGI.
ProtClustDB	PRK00802.
Family and domain databases
Gene3D	3.10.300.10. 1 hit.
HAMAP	MF_00527. 3MGH.
InterPro	IPR011034. Formyl_transferase_C-like. IPR003180. PurDNA_glycsylse. [Graphical view]
PANTHER	PTHR10429. PTHR10429. 1 hit.
Pfam	PF02245. Pur_DNA_glyco. 1 hit. [Graphical view]
SUPFAM	SSF50486. FMT_C_like. 1 hit.
TIGRFAMs	TIGR00567. 3mg. 1 hit.
ProtoNet	Search...

Entry information

Entry name

3MGH_RICFE

Accession

Primary (citable) accession number: Q4UM12

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 12, 2006
Last sequence update:	July 5, 2005
Last modified:	May 1, 2013
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program