ID   NUOC_RICFE              Reviewed;         207 AA.
AC   Q4UM07;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2005, sequence version 1.
DT   16-JUN-2009, entry version 29.
DE   RecName: Full=NADH-quinone oxidoreductase subunit C;
DE            EC=1.6.99.5;
DE   AltName: Full=NADH dehydrogenase I subunit C;
DE   AltName: Full=NDH-1 subunit C;
GN   Name=nuoC; OrderedLocusNames=RF_0565;
OS   Rickettsia felis (Rickettsia azadi).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
OX   NCBI_TaxID=42862;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC VR-1525 / URRWXCal2;
RX   PubMed=15984913; DOI=10.1371/journal.pbio.0030248;
RA   Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E.,
RA   Parinello H., Claverie J.-M., Raoult D.;
RT   "The genome sequence of Rickettsia felis identifies the first putative
RT   conjugative plasmid in an obligate intracellular parasite.";
RL   PLoS Biol. 3:1-12(2005).
CC   -!- FUNCTION: NDH-1 shuttles electrons from NADH, via FMN and iron-
CC       sulfur (Fe-S) centers, to quinones in the respiratory chain. The
CC       immediate electron acceptor for the enzyme in this species is
CC       believed to be ubiquinone. Couples the redox reaction to proton
CC       translocation (for every two electrons transferred, four hydrogen
CC       ions are translocated across the cytoplasmic membrane), and thus
CC       conserves the redox energy in a proton gradient (By similarity).
CC   -!- CATALYTIC ACTIVITY: NADH + quinone = NAD(+) + quinol.
CC   -!- SUBUNIT: NDH-1 is composed of 14 different subunits. Subunits
CC       nuoB, C, D, E, F, and G constitute the peripheral sector of the
CC       complex (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Peripheral membrane
CC       protein; Cytoplasmic side (By similarity).
CC   -!- SIMILARITY: Belongs to the complex I 30 kDa subunit family.
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DR   EMBL; CP000053; AAY61416.1; -; Genomic_DNA.
DR   RefSeq; YP_246581.1; -.
DR   GeneID; 3400344; -.
DR   GenomeReviews; CP000053_GR; RF_0565.
DR   KEGG; rfe:RF_0565; -.
DR   NMPDR; fig|315456.3.peg.399; -.
DR   HOGENOM; Q4UM07; -.
DR   OMA; Q4UM07; LTGYTQV.
DR   BioCyc; RFEL315456:RF_0565-MON; -.
DR   BRENDA; 1.6.99.5; 297363.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR   GO; GO:0048038; F:quinone binding; IEA:UniProtKB-KW.
DR   GO; GO:0055114; P:oxidation reduction; IEA:HAMAP.
DR   GO; GO:0019684; P:photosynthesis, light reaction; IEA:HAMAP.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
DR   HAMAP; MF_01357; -; 1.
DR   InterPro; IPR010218; NADH_DH_csu.
DR   InterPro; IPR001268; NADH_UbQ_OxRdtase_30kDa_su.
DR   Pfam; PF00329; Complex1_30kDa; 1.
DR   ProDom; PD001581; Complex1_30K; 1.
DR   TIGRFAMs; TIGR01961; NuoC_fam; 1.
DR   PROSITE; PS00542; COMPLEX1_30K; FALSE_NEG.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Complete proteome; Membrane; NAD;
KW   Oxidoreductase; Quinone; Transport; Ubiquinone.
FT   CHAIN         1    207       NADH-quinone oxidoreductase subunit C.
FT                                /FTId=PRO_0000287859.
SQ   SEQUENCE   207 AA;  24256 MW;  DD092E30E558D59A CRC64;
     MTLDKLIEKL AAKSSILITP IIVKDYLAYQ VEPNFLLPFL KALKESEELR FTVLTDLFGT
     DFPERDKRFE VIYNLLSLKL NKRLIIKVYI SEKETIPSAM NIFNASCWYE REVYDMYGVN
     FDGNDDKRRI LTDYEFEGHP LRKDFPLTGY TQVKYDEKLK KVAYEPVDLD IEYREFDFSS
     HWHSPSYVLP GDEKATDVIP AKAGIQK
//