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Q4ULR7 (CDSA_RICFE) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphatidate cytidylyltransferase

EC=2.7.7.41
Alternative name(s):
CDP-DAG synthase
CDP-DG synthase
CDP-diacylglycerol synthase
Short name=CDS
CDP-diglyceride pyrophosphorylase
CDP-diglyceride synthase
CTP:phosphatidate cytidylyltransferase
Gene names
Name:cdsA
Ordered Locus Names:RF_0655
OrganismRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) [Complete proteome] [HAMAP]
Taxonomic identifier315456 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group

Protein attributes

Sequence length227 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

CTP + phosphatidate = diphosphate + CDP-diacylglycerol.

Pathway

Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3.

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the CDS family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 227227Phosphatidate cytidylyltransferase
PRO_0000281058

Regions

Transmembrane31 – 5121Helical; Potential
Transmembrane65 – 8521Helical; Potential
Transmembrane93 – 11321Helical; Potential
Transmembrane131 – 15121Helical; Potential
Transmembrane165 – 18521Helical; Potential
Transmembrane206 – 22621Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q4ULR7 [UniParc].

Last modified July 5, 2005. Version 1.
Checksum: 44E64F36CDE950FE

FASTA22725,624
        10         20         30         40         50         60 
MITQKGKEHL AKDKQNIYLR ILSGIVLVPL FVIAILWFKP LFYILMILVG MGMLSEWYNM 

        70         80         90        100        110        120 
TYSSIPYLLI GLIIIPIPIS LLTFLSMEDT NRWLIMLYFC IIWSVDSFAM IGGKTFKGAK 

       130        140        150        160        170        180 
LAPKISPKKT WSGLVTGVLS AGLVAVLASF IPNFHIENYY FSNKIYLFII SCILALIAQS 

       190        200        210        220 
SDLFISYLKR KFNIKDSGHI IPGHGGVLDR FDSIILTAPV LFFISIL 

« Hide

References

[1]"The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-1525 / URRWXCal2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000053 Genomic DNA. Translation: AAY61506.1.
RefSeqYP_246671.1. NC_007109.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING315456.RF_0655.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAY61506; AAY61506; RF_0655.
GeneID3400663.
KEGGrfe:RF_0655.
PATRIC17891912. VBIRicFel64634_0785.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0575.
HOGENOMHOG000006169.
KOK00981.
OMAIAILWCK.
OrthoDBEOG6TBHJT.
ProtClustDBCLSK870917.

Enzyme and pathway databases

BioCycRFEL315456:GKEK-672-MONOMER.
UniPathwayUPA00557; UER00614.

Family and domain databases

InterProIPR000374. PC_trans.
[Graphical view]
PfamPF01148. CTP_transf_1. 1 hit.
[Graphical view]
PROSITEPS01315. CDS. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCDSA_RICFE
AccessionPrimary (citable) accession number: Q4ULR7
Entry history
Integrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: July 5, 2005
Last modified: February 19, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia felis (Rickettsia azadi)

Rickettsia felis (strain URRWXCal2): entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways