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Q4ULR3 (ILVE_RICFE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable branched-chain-amino-acid aminotransferase

Short name=BCAT
EC=2.6.1.42
Gene names
Name:ilvE
Ordered Locus Names:RF_0659
OrganismRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) [Complete proteome] [HAMAP]
Taxonomic identifier315456 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group

Protein attributes

Sequence length290 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Acts on leucine, isoleucine and valine By similarity.

Catalytic activity

L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate.

L-isoleucine + 2-oxoglutarate = (S)-3-methyl-2-oxopentanoate + L-glutamate.

L-valine + 2-oxoglutarate = 3-methyl-2-oxobutanoate + L-glutamate.

Cofactor

Pyridoxal phosphate By similarity.

Pathway

Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 4/4.

Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 4/4.

Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 4/4.

Sequence similarities

Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 290290Probable branched-chain-amino-acid aminotransferase
PRO_0000280901

Amino acid modifications

Modified residue1551N6-(pyridoxal phosphate)lysine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q4ULR3 [UniParc].

Last modified July 5, 2005. Version 1.
Checksum: D1C631A4DBDEF5F8

FASTA29033,046
        10         20         30         40         50         60 
MTMIKLEQIF WHVWINGDLV PYQFARIHVL THSLHYSGSV FEGERAYNGK VFKLKEHTER 

        70         80         90        100        110        120 
LIKSAEALGL KVPYSVDEII KAHELVIKQN NIKDAYIRPL IWCGDESLNI TNPDLSTNLL 

       130        140        150        160        170        180 
IAGIPSMPRS FEKGINLHVG RWRKAIPDST PVQSKSAAQY NMAITSKKEA KALGYDDALL 

       190        200        210        220        230        240 
LDYEGYIAEC TTTNIFFVKD KTLYTPIADR FLNGITRQTI IEIAKDLGLE VKEERLKLEQ 

       250        260        270        280        290 
IENFTGCFVT GTAIEVQNID SIDLGNKKIT FDDHQIADRL KKEYGRIVRE 

« Hide

References

[1]"The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-1525 / URRWXCal2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000053 Genomic DNA. Translation: AAY61510.1.
RefSeqYP_246675.1. NC_007109.1.

3D structure databases

ProteinModelPortalQ4ULR3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING315456.RF_0659.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAY61510; AAY61510; RF_0659.
GeneID3400667.
KEGGrfe:RF_0659.
PATRIC17891924. VBIRicFel64634_0791.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0115.
HOGENOMHOG000276706.
KOK00826.
OMAKLTEHSE.
OrthoDBEOG67MF3R.

Enzyme and pathway databases

BioCycRFEL315456:GKEK-676-MONOMER.
UniPathwayUPA00047; UER00058.
UPA00048; UER00073.
UPA00049; UER00062.

Family and domain databases

InterProIPR001544. Aminotrans_IV.
IPR018300. Aminotrans_IV_CS.
IPR005785. B_amino_transI.
[Graphical view]
PANTHERPTHR11825. PTHR11825. 1 hit.
PfamPF01063. Aminotran_4. 1 hit.
[Graphical view]
SUPFAMSSF56752. SSF56752. 1 hit.
TIGRFAMsTIGR01122. ilvE_I. 1 hit.
PROSITEPS00770. AA_TRANSFER_CLASS_4. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameILVE_RICFE
AccessionPrimary (citable) accession number: Q4ULR3
Entry history
Integrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: July 5, 2005
Last modified: May 14, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia felis (Rickettsia azadi)

Rickettsia felis (strain URRWXCal2): entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways