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Q4ULQ8 (SUCD_RICFE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Succinyl-CoA ligase [ADP-forming] subunit alpha

EC=6.2.1.5
Alternative name(s):
Succinyl-CoA synthetase subunit alpha
Short name=SCS-alpha
Gene names
Name:sucD
Ordered Locus Names:RF_0664
OrganismRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) [Complete proteome] [HAMAP]
Taxonomic identifier315456 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group

Protein attributes

Sequence length292 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + succinate + CoA = ADP + phosphate + succinyl-CoA.

Subunit structure

Heterotetramer of two alpha and two beta subunits By similarity.

Sequence similarities

Belongs to the succinate/malate CoA ligase alpha subunit family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 292292Succinyl-CoA ligase [ADP-forming] subunit alpha
PRO_0000286489

Sites

Active site2481Tele-phosphohistidine intermediate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q4ULQ8 [UniParc].

Last modified July 5, 2005. Version 1.
Checksum: F26E7227B10DD277

FASTA29230,165
        10         20         30         40         50         60 
MAILINKKTK VICQGFTGSQ GTFHSEQAIA YGTNMVGGVT PGKGGHTHLD LPVYNTVHEA 

        70         80         90        100        110        120 
KAKTGANASV IYVPPGFAAD SILEAIDAEI EVVVCITEGI PVLDMVKVKR ALVGSKTRLI 

       130        140        150        160        170        180 
GPNCPGVITP GECKIGIMPG HIHKRGTIGI VSRSGTLTYE AVAQTTAVGL GQSTCVGIGG 

       190        200        210        220        230        240 
DPVNGTNFVD CIDMFLKDDE TKAIIMIGEI GGNAEEDAAE FIKQSKIKKP IVSFIAGITA 

       250        260        270        280        290 
PPGKRMGHAG AIIAGGKGSA EDKLEALQSA GVTITRSPAD IGKTMFDLLN KG 

« Hide

References

[1]"The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-1525 / URRWXCal2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000053 Genomic DNA. Translation: AAY61515.1.
RefSeqYP_246680.1. NC_007109.1.

3D structure databases

ProteinModelPortalQ4ULQ8.
SMRQ4ULQ8. Positions 2-289.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING315456.RF_0664.

Proteomic databases

PRIDEQ4ULQ8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAY61515; AAY61515; RF_0664.
GeneID3401289.
KEGGrfe:RF_0664.
PATRIC17891938. VBIRicFel64634_0798.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0074.
HOGENOMHOG000239685.
KOK01902.
OMAFEQDPQT.
OrthoDBEOG644ZT0.

Enzyme and pathway databases

BioCycRFEL315456:GKEK-681-MONOMER.

Family and domain databases

Gene3D3.40.50.261. 1 hit.
3.40.50.720. 1 hit.
InterProIPR017440. Cit_synth/succinyl-CoA_lig_AS.
IPR003781. CoA-bd.
IPR005810. CoA_lig_alpha.
IPR005811. CoA_ligase.
IPR016040. NAD(P)-bd_dom.
IPR016102. Succinyl-CoA_synth-like.
[Graphical view]
PfamPF02629. CoA_binding. 1 hit.
PF00549. Ligase_CoA. 1 hit.
[Graphical view]
PIRSFPIRSF001553. SucCS_alpha. 1 hit.
PRINTSPR01798. SCOASYNTHASE.
SMARTSM00881. CoA_binding. 1 hit.
[Graphical view]
SUPFAMSSF52210. SSF52210. 1 hit.
TIGRFAMsTIGR01019. sucCoAalpha. 1 hit.
PROSITEPS01216. SUCCINYL_COA_LIG_1. 1 hit.
PS00399. SUCCINYL_COA_LIG_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSUCD_RICFE
AccessionPrimary (citable) accession number: Q4ULQ8
Entry history
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: July 5, 2005
Last modified: May 14, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia felis (Rickettsia azadi)

Rickettsia felis (strain URRWXCal2): entries and gene names