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Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei40NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processtRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
Alternative name(s):
tRNA pseudouridine(55) synthaseUniRule annotation
Short name:
Psi55 synthaseUniRule annotation
tRNA pseudouridylate synthaseUniRule annotation
tRNA-uridine isomeraseUniRule annotation
Gene namesi
Name:truBUniRule annotation
Ordered Locus Names:RF_0723
OrganismiRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Taxonomic identifieri315456 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
Proteomesi
  • UP000008548 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002293791 – 339tRNA pseudouridine synthase BAdd BLAST339

Interactioni

Protein-protein interaction databases

STRINGi315456.RF_0723.

Structurei

3D structure databases

ProteinModelPortaliQ4ULJ9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini262 – 307RPE1 insertAdd BLAST46

Sequence similaritiesi

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D0T. Bacteria.
COG0130. LUCA.
HOGENOMiHOG000231225.
KOiK03177.
OrthoDBiPOG0939005V.

Family and domain databases

HAMAPiMF_01080. TruB_bact. 1 hit.
InterProiView protein in InterPro
IPR020103. PsdUridine_synth_cat_dom.
IPR002501. PsdUridine_synth_N.
IPR005728. Rickett_RPE.
IPR014780. tRNA_psdUridine_synth_TruB.
IPR032819. TruB_C.
PANTHERiPTHR13767. PTHR13767. 1 hit.
PfamiView protein in Pfam
PF16198. TruB_C_2. 1 hit.
PF01509. TruB_N. 1 hit.
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR01045. RPE1. 1 hit.
TIGR00431. TruB. 1 hit.

Sequencei

Sequence statusi: Complete.

Q4ULJ9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNSYWLNIYK PRGISSAKLV SMVKKILGKE VKVGHAGTLD VEAEGILPLA
60 70 80 90 100
VGEATKLIQL LIDAKKTYIF TVKFGTKTDS GDYAGTVIAT KDYIPSQEEA
110 120 130 140 150
YNVCSKFIGN VTQIPPAFSA LKVNGVRAYK LAREGKEVEL KPRNITIYNL
160 170 180 190 200
KCLNFDEKNA TASYYTECSK GTYIRTLAED LALSLQSLGF VIELRRTQVG
210 220 230 240 250
IFKEENAIRI KSPDEITKNF LEEKSIKIEA ILDDILVLDA TDSQAQQIKY
260 270 280 290 300
GQKCLFNYEE DFRRLSKFAY REEFEENTER STAAYTLVRE DANTGLTYKL
310 320 330
PLEVELSVSL LWVRYKGNLL AIGSLNKSCF NSLRVFNLL
Length:339
Mass (Da):38,192
Last modified:February 20, 2007 - v2
Checksum:iDCFEFC3AB19590E6
GO

Sequence cautioni

The sequence AAY61574 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000053 Genomic DNA. Translation: AAY61574.1. Different initiation.
RefSeqiWP_039594988.1. NC_007109.1.

Genome annotation databases

EnsemblBacteriaiAAY61574; AAY61574; RF_0723.
KEGGirfe:RF_0723.
PATRICi17892086. VBIRicFel64634_0871.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000053 Genomic DNA. Translation: AAY61574.1. Different initiation.
RefSeqiWP_039594988.1. NC_007109.1.

3D structure databases

ProteinModelPortaliQ4ULJ9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi315456.RF_0723.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAY61574; AAY61574; RF_0723.
KEGGirfe:RF_0723.
PATRICi17892086. VBIRicFel64634_0871.

Phylogenomic databases

eggNOGiENOG4105D0T. Bacteria.
COG0130. LUCA.
HOGENOMiHOG000231225.
KOiK03177.
OrthoDBiPOG0939005V.

Family and domain databases

HAMAPiMF_01080. TruB_bact. 1 hit.
InterProiView protein in InterPro
IPR020103. PsdUridine_synth_cat_dom.
IPR002501. PsdUridine_synth_N.
IPR005728. Rickett_RPE.
IPR014780. tRNA_psdUridine_synth_TruB.
IPR032819. TruB_C.
PANTHERiPTHR13767. PTHR13767. 1 hit.
PfamiView protein in Pfam
PF16198. TruB_C_2. 1 hit.
PF01509. TruB_N. 1 hit.
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR01045. RPE1. 1 hit.
TIGR00431. TruB. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiTRUB_RICFE
AccessioniPrimary (citable) accession number: Q4ULJ9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: February 20, 2007
Last modified: February 15, 2017
This is version 72 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia felis (Rickettsia azadi)
    Rickettsia felis (strain URRWXCal2): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.