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Protein

ADP,ATP carrier protein 4

Gene

tlcD

Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism (By similarity).By similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Transport

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
ADP,ATP carrier protein 4
Alternative name(s):
ADP/ATP translocase 4
Gene namesi
Name:tlcD
Synonyms:tlc4
Ordered Locus Names:RF_0724
OrganismiRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Taxonomic identifieri315456 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
Proteomesi
  • UP000008548 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei34 – 54HelicalSequence analysisAdd BLAST21
Transmembranei71 – 91HelicalSequence analysisAdd BLAST21
Transmembranei102 – 122HelicalSequence analysisAdd BLAST21
Transmembranei157 – 177HelicalSequence analysisAdd BLAST21
Transmembranei192 – 212HelicalSequence analysisAdd BLAST21
Transmembranei231 – 251HelicalSequence analysisAdd BLAST21
Transmembranei296 – 316HelicalSequence analysisAdd BLAST21
Transmembranei330 – 350HelicalSequence analysisAdd BLAST21
Transmembranei361 – 381HelicalSequence analysisAdd BLAST21
Transmembranei390 – 410HelicalSequence analysisAdd BLAST21
Transmembranei453 – 473HelicalSequence analysisAdd BLAST21
Transmembranei476 – 496HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002864761 – 511ADP,ATP carrier protein 4Add BLAST511

Interactioni

Protein-protein interaction databases

STRINGi315456.RF_0724.

Family & Domainsi

Sequence similaritiesi

Belongs to the ADP/ATP translocase tlc family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4107FWK. Bacteria.
COG3202. LUCA.
HOGENOMiHOG000238123.
KOiK03301.
OMAiFLMTAIY.
OrthoDBiPOG091H0NNH.

Family and domain databases

InterProiIPR004667. ADP_ATP_car.
IPR020846. MFS_dom.
[Graphical view]
PANTHERiPTHR31187. PTHR31187. 1 hit.
PfamiPF03219. TLC. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00769. AAA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q4ULJ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTINSSNIEN PPSKINSRFS KLTDYIWPIK RHEVSKFLFI TLLMFCILFI
60 70 80 90 100
QNLIRALKDS IVTTMIGAET ISFLKFWGVM PSAFLMTAIY VKLVNRMKAE
110 120 130 140 150
NIFYLIISIF LAFFALFAYV IFPNHEILHL SPVTVQNLTA NLLNLKWFIL
160 170 180 190 200
LLSKWSFSLF YIIAELWPNV VFALLFWQFV NNITTVEESK RFYPLFGLLS
210 220 230 240 250
QTGIYLAGQF LENLSNINDY VTNKFALQSS FHTLSIQIIL TIVLILGIIA
260 270 280 290 300
IKTFWLLNHK VLDKEHMALL KFKAKKKSMT IAESFQMILS SRHIRLIATL
310 320 330 340 350
LICYGIAINL VEGPWKAAAT KIYKTPTEYA AFIGSYLSYT GVFTILFVVL
360 370 380 390 400
GSNIVRRLGW FTAAVITPLI VFITGILFFA VNNFEGFAGL IIANFILTDP
410 420 430 440 450
ALIAITIGAI QNVLSKSSKY TLFDSTKEMA YVPLDPEIKI KGKAAADVIG
460 470 480 490 500
TKLGKSGSAF LQSLVFIILP SASYQSISIC LMIIFIITCL TWLWATKELN
510
KEYKNSIKFS Q
Length:511
Mass (Da):57,870
Last modified:July 5, 2005 - v1
Checksum:iB64A98B2F1F04533
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000053 Genomic DNA. Translation: AAY61575.1.
RefSeqiWP_011271054.1. NC_007109.1.

Genome annotation databases

EnsemblBacteriaiAAY61575; AAY61575; RF_0724.
KEGGirfe:RF_0724.
PATRICi17892090. VBIRicFel64634_0873.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000053 Genomic DNA. Translation: AAY61575.1.
RefSeqiWP_011271054.1. NC_007109.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi315456.RF_0724.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAY61575; AAY61575; RF_0724.
KEGGirfe:RF_0724.
PATRICi17892090. VBIRicFel64634_0873.

Phylogenomic databases

eggNOGiENOG4107FWK. Bacteria.
COG3202. LUCA.
HOGENOMiHOG000238123.
KOiK03301.
OMAiFLMTAIY.
OrthoDBiPOG091H0NNH.

Family and domain databases

InterProiIPR004667. ADP_ATP_car.
IPR020846. MFS_dom.
[Graphical view]
PANTHERiPTHR31187. PTHR31187. 1 hit.
PfamiPF03219. TLC. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00769. AAA. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiTLCD_RICFE
AccessioniPrimary (citable) accession number: Q4ULJ8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: July 5, 2005
Last modified: November 2, 2016
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia felis (Rickettsia azadi)
    Rickettsia felis (strain URRWXCal2): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.