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Q4ULJ8

- TLCD_RICFE

UniProt

Q4ULJ8 - TLCD_RICFE

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Protein

ADP,ATP carrier protein 4

Gene

tlcD

Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism (By similarity).By similarity

GO - Molecular functioni

  1. ATP:ADP antiporter activity Source: InterPro
  2. ATP binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transport

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciRFEL315456:GKEK-742-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
ADP,ATP carrier protein 4
Alternative name(s):
ADP/ATP translocase 4
Gene namesi
Name:tlcD
Synonyms:tlc4
Ordered Locus Names:RF_0724
OrganismiRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Taxonomic identifieri315456 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
ProteomesiUP000008548: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei34 – 5421HelicalSequence AnalysisAdd
BLAST
Transmembranei71 – 9121HelicalSequence AnalysisAdd
BLAST
Transmembranei102 – 12221HelicalSequence AnalysisAdd
BLAST
Transmembranei157 – 17721HelicalSequence AnalysisAdd
BLAST
Transmembranei192 – 21221HelicalSequence AnalysisAdd
BLAST
Transmembranei231 – 25121HelicalSequence AnalysisAdd
BLAST
Transmembranei296 – 31621HelicalSequence AnalysisAdd
BLAST
Transmembranei330 – 35021HelicalSequence AnalysisAdd
BLAST
Transmembranei361 – 38121HelicalSequence AnalysisAdd
BLAST
Transmembranei390 – 41021HelicalSequence AnalysisAdd
BLAST
Transmembranei453 – 47321HelicalSequence AnalysisAdd
BLAST
Transmembranei476 – 49621HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 511511ADP,ATP carrier protein 4PRO_0000286476Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi315456.RF_0724.

Family & Domainsi

Sequence similaritiesi

Belongs to the ADP/ATP translocase tlc family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG3202.
HOGENOMiHOG000238123.
KOiK03301.
OMAiFLMTAIY.
OrthoDBiEOG6BCSND.

Family and domain databases

InterProiIPR004667. ADP_ATP_car.
IPR016196. MFS_dom_general_subst_transpt.
[Graphical view]
PfamiPF03219. TLC. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00769. AAA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q4ULJ8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTINSSNIEN PPSKINSRFS KLTDYIWPIK RHEVSKFLFI TLLMFCILFI
60 70 80 90 100
QNLIRALKDS IVTTMIGAET ISFLKFWGVM PSAFLMTAIY VKLVNRMKAE
110 120 130 140 150
NIFYLIISIF LAFFALFAYV IFPNHEILHL SPVTVQNLTA NLLNLKWFIL
160 170 180 190 200
LLSKWSFSLF YIIAELWPNV VFALLFWQFV NNITTVEESK RFYPLFGLLS
210 220 230 240 250
QTGIYLAGQF LENLSNINDY VTNKFALQSS FHTLSIQIIL TIVLILGIIA
260 270 280 290 300
IKTFWLLNHK VLDKEHMALL KFKAKKKSMT IAESFQMILS SRHIRLIATL
310 320 330 340 350
LICYGIAINL VEGPWKAAAT KIYKTPTEYA AFIGSYLSYT GVFTILFVVL
360 370 380 390 400
GSNIVRRLGW FTAAVITPLI VFITGILFFA VNNFEGFAGL IIANFILTDP
410 420 430 440 450
ALIAITIGAI QNVLSKSSKY TLFDSTKEMA YVPLDPEIKI KGKAAADVIG
460 470 480 490 500
TKLGKSGSAF LQSLVFIILP SASYQSISIC LMIIFIITCL TWLWATKELN
510
KEYKNSIKFS Q
Length:511
Mass (Da):57,870
Last modified:July 5, 2005 - v1
Checksum:iB64A98B2F1F04533
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000053 Genomic DNA. Translation: AAY61575.1.
RefSeqiWP_011271054.1. NC_007109.1.
YP_246740.1. NC_007109.1.

Genome annotation databases

EnsemblBacteriaiAAY61575; AAY61575; RF_0724.
GeneIDi3401098.
KEGGirfe:RF_0724.
PATRICi17892090. VBIRicFel64634_0873.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000053 Genomic DNA. Translation: AAY61575.1 .
RefSeqi WP_011271054.1. NC_007109.1.
YP_246740.1. NC_007109.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 315456.RF_0724.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAY61575 ; AAY61575 ; RF_0724 .
GeneIDi 3401098.
KEGGi rfe:RF_0724.
PATRICi 17892090. VBIRicFel64634_0873.

Phylogenomic databases

eggNOGi COG3202.
HOGENOMi HOG000238123.
KOi K03301.
OMAi FLMTAIY.
OrthoDBi EOG6BCSND.

Enzyme and pathway databases

BioCyci RFEL315456:GKEK-742-MONOMER.

Family and domain databases

InterProi IPR004667. ADP_ATP_car.
IPR016196. MFS_dom_general_subst_transpt.
[Graphical view ]
Pfami PF03219. TLC. 1 hit.
[Graphical view ]
SUPFAMi SSF103473. SSF103473. 1 hit.
TIGRFAMsi TIGR00769. AAA. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
    Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
    PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-1525 / URRWXCal2.

Entry informationi

Entry nameiTLCD_RICFE
AccessioniPrimary (citable) accession number: Q4ULJ8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: July 5, 2005
Last modified: October 29, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia felis (Rickettsia azadi)
    Rickettsia felis (strain URRWXCal2): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3