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Q4ULJ8

- TLCD_RICFE

UniProt

Q4ULJ8 - TLCD_RICFE

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Protein

ADP,ATP carrier protein 4

Gene
tlcD, tlc4, RF_0724
Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism By similarity.

GO - Molecular functioni

  1. ATP:ADP antiporter activity Source: InterPro
  2. ATP binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transport

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciRFEL315456:GKEK-742-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
ADP,ATP carrier protein 4
Alternative name(s):
ADP/ATP translocase 4
Gene namesi
Name:tlcD
Synonyms:tlc4
Ordered Locus Names:RF_0724
OrganismiRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Taxonomic identifieri315456 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
ProteomesiUP000008548: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei34 – 5421Helical; Reviewed predictionAdd
BLAST
Transmembranei71 – 9121Helical; Reviewed predictionAdd
BLAST
Transmembranei102 – 12221Helical; Reviewed predictionAdd
BLAST
Transmembranei157 – 17721Helical; Reviewed predictionAdd
BLAST
Transmembranei192 – 21221Helical; Reviewed predictionAdd
BLAST
Transmembranei231 – 25121Helical; Reviewed predictionAdd
BLAST
Transmembranei296 – 31621Helical; Reviewed predictionAdd
BLAST
Transmembranei330 – 35021Helical; Reviewed predictionAdd
BLAST
Transmembranei361 – 38121Helical; Reviewed predictionAdd
BLAST
Transmembranei390 – 41021Helical; Reviewed predictionAdd
BLAST
Transmembranei453 – 47321Helical; Reviewed predictionAdd
BLAST
Transmembranei476 – 49621Helical; Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 511511ADP,ATP carrier protein 4PRO_0000286476Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi315456.RF_0724.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG3202.
HOGENOMiHOG000238123.
KOiK03301.
OMAiFLMTAIY.
OrthoDBiEOG6BCSND.

Family and domain databases

InterProiIPR004667. ADP_ATP_car.
IPR016196. MFS_dom_general_subst_transpt.
[Graphical view]
PfamiPF03219. TLC. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00769. AAA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q4ULJ8-1 [UniParc]FASTAAdd to Basket

« Hide

MTINSSNIEN PPSKINSRFS KLTDYIWPIK RHEVSKFLFI TLLMFCILFI    50
QNLIRALKDS IVTTMIGAET ISFLKFWGVM PSAFLMTAIY VKLVNRMKAE 100
NIFYLIISIF LAFFALFAYV IFPNHEILHL SPVTVQNLTA NLLNLKWFIL 150
LLSKWSFSLF YIIAELWPNV VFALLFWQFV NNITTVEESK RFYPLFGLLS 200
QTGIYLAGQF LENLSNINDY VTNKFALQSS FHTLSIQIIL TIVLILGIIA 250
IKTFWLLNHK VLDKEHMALL KFKAKKKSMT IAESFQMILS SRHIRLIATL 300
LICYGIAINL VEGPWKAAAT KIYKTPTEYA AFIGSYLSYT GVFTILFVVL 350
GSNIVRRLGW FTAAVITPLI VFITGILFFA VNNFEGFAGL IIANFILTDP 400
ALIAITIGAI QNVLSKSSKY TLFDSTKEMA YVPLDPEIKI KGKAAADVIG 450
TKLGKSGSAF LQSLVFIILP SASYQSISIC LMIIFIITCL TWLWATKELN 500
KEYKNSIKFS Q 511
Length:511
Mass (Da):57,870
Last modified:July 5, 2005 - v1
Checksum:iB64A98B2F1F04533
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000053 Genomic DNA. Translation: AAY61575.1.
RefSeqiWP_011271054.1. NC_007109.1.
YP_246740.1. NC_007109.1.

Genome annotation databases

EnsemblBacteriaiAAY61575; AAY61575; RF_0724.
GeneIDi3401098.
KEGGirfe:RF_0724.
PATRICi17892090. VBIRicFel64634_0873.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000053 Genomic DNA. Translation: AAY61575.1 .
RefSeqi WP_011271054.1. NC_007109.1.
YP_246740.1. NC_007109.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 315456.RF_0724.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAY61575 ; AAY61575 ; RF_0724 .
GeneIDi 3401098.
KEGGi rfe:RF_0724.
PATRICi 17892090. VBIRicFel64634_0873.

Phylogenomic databases

eggNOGi COG3202.
HOGENOMi HOG000238123.
KOi K03301.
OMAi FLMTAIY.
OrthoDBi EOG6BCSND.

Enzyme and pathway databases

BioCyci RFEL315456:GKEK-742-MONOMER.

Family and domain databases

InterProi IPR004667. ADP_ATP_car.
IPR016196. MFS_dom_general_subst_transpt.
[Graphical view ]
Pfami PF03219. TLC. 1 hit.
[Graphical view ]
SUPFAMi SSF103473. SSF103473. 1 hit.
TIGRFAMsi TIGR00769. AAA. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
    Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
    PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-1525 / URRWXCal2.

Entry informationi

Entry nameiTLCD_RICFE
AccessioniPrimary (citable) accession number: Q4ULJ8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: July 5, 2005
Last modified: September 3, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia felis (Rickettsia azadi)
    Rickettsia felis (strain URRWXCal2): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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