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Q4ULJ8

- TLCD_RICFE

UniProt

Q4ULJ8 - TLCD_RICFE

Protein

ADP,ATP carrier protein 4

Gene

tlcD

Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 53 (01 Oct 2014)
      Sequence version 1 (05 Jul 2005)
      Previous versions | rss
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    Functioni

    Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism By similarity.By similarity

    GO - Molecular functioni

    1. ATP:ADP antiporter activity Source: InterPro
    2. ATP binding Source: UniProtKB-KW

    Keywords - Biological processi

    Transport

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciRFEL315456:GKEK-742-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    ADP,ATP carrier protein 4
    Alternative name(s):
    ADP/ATP translocase 4
    Gene namesi
    Name:tlcD
    Synonyms:tlc4
    Ordered Locus Names:RF_0724
    OrganismiRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
    Taxonomic identifieri315456 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
    ProteomesiUP000008548: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 511511ADP,ATP carrier protein 4PRO_0000286476Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi315456.RF_0724.

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei34 – 5421HelicalSequence AnalysisAdd
    BLAST
    Transmembranei71 – 9121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei102 – 12221HelicalSequence AnalysisAdd
    BLAST
    Transmembranei157 – 17721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei192 – 21221HelicalSequence AnalysisAdd
    BLAST
    Transmembranei231 – 25121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei296 – 31621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei330 – 35021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei361 – 38121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei390 – 41021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei453 – 47321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei476 – 49621HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ADP/ATP translocase tlc family.Curated

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG3202.
    HOGENOMiHOG000238123.
    KOiK03301.
    OMAiFLMTAIY.
    OrthoDBiEOG6BCSND.

    Family and domain databases

    InterProiIPR004667. ADP_ATP_car.
    IPR016196. MFS_dom_general_subst_transpt.
    [Graphical view]
    PfamiPF03219. TLC. 1 hit.
    [Graphical view]
    SUPFAMiSSF103473. SSF103473. 1 hit.
    TIGRFAMsiTIGR00769. AAA. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q4ULJ8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTINSSNIEN PPSKINSRFS KLTDYIWPIK RHEVSKFLFI TLLMFCILFI    50
    QNLIRALKDS IVTTMIGAET ISFLKFWGVM PSAFLMTAIY VKLVNRMKAE 100
    NIFYLIISIF LAFFALFAYV IFPNHEILHL SPVTVQNLTA NLLNLKWFIL 150
    LLSKWSFSLF YIIAELWPNV VFALLFWQFV NNITTVEESK RFYPLFGLLS 200
    QTGIYLAGQF LENLSNINDY VTNKFALQSS FHTLSIQIIL TIVLILGIIA 250
    IKTFWLLNHK VLDKEHMALL KFKAKKKSMT IAESFQMILS SRHIRLIATL 300
    LICYGIAINL VEGPWKAAAT KIYKTPTEYA AFIGSYLSYT GVFTILFVVL 350
    GSNIVRRLGW FTAAVITPLI VFITGILFFA VNNFEGFAGL IIANFILTDP 400
    ALIAITIGAI QNVLSKSSKY TLFDSTKEMA YVPLDPEIKI KGKAAADVIG 450
    TKLGKSGSAF LQSLVFIILP SASYQSISIC LMIIFIITCL TWLWATKELN 500
    KEYKNSIKFS Q 511
    Length:511
    Mass (Da):57,870
    Last modified:July 5, 2005 - v1
    Checksum:iB64A98B2F1F04533
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000053 Genomic DNA. Translation: AAY61575.1.
    RefSeqiWP_011271054.1. NC_007109.1.
    YP_246740.1. NC_007109.1.

    Genome annotation databases

    EnsemblBacteriaiAAY61575; AAY61575; RF_0724.
    GeneIDi3401098.
    KEGGirfe:RF_0724.
    PATRICi17892090. VBIRicFel64634_0873.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000053 Genomic DNA. Translation: AAY61575.1 .
    RefSeqi WP_011271054.1. NC_007109.1.
    YP_246740.1. NC_007109.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 315456.RF_0724.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAY61575 ; AAY61575 ; RF_0724 .
    GeneIDi 3401098.
    KEGGi rfe:RF_0724.
    PATRICi 17892090. VBIRicFel64634_0873.

    Phylogenomic databases

    eggNOGi COG3202.
    HOGENOMi HOG000238123.
    KOi K03301.
    OMAi FLMTAIY.
    OrthoDBi EOG6BCSND.

    Enzyme and pathway databases

    BioCyci RFEL315456:GKEK-742-MONOMER.

    Family and domain databases

    InterProi IPR004667. ADP_ATP_car.
    IPR016196. MFS_dom_general_subst_transpt.
    [Graphical view ]
    Pfami PF03219. TLC. 1 hit.
    [Graphical view ]
    SUPFAMi SSF103473. SSF103473. 1 hit.
    TIGRFAMsi TIGR00769. AAA. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
      Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
      PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC VR-1525 / URRWXCal2.

    Entry informationi

    Entry nameiTLCD_RICFE
    AccessioniPrimary (citable) accession number: Q4ULJ8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 15, 2007
    Last sequence update: July 5, 2005
    Last modified: October 1, 2014
    This is version 53 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Rickettsia felis (Rickettsia azadi)
      Rickettsia felis (strain URRWXCal2): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3