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Protein

Superoxide dismutase [Mn/Fe]

Gene

sodB

Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.

Cofactori

Mn2+By similarity, Fe2+By similarityNote: Binds 1 Mn2+ or Fe2+ ion per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi38Manganese or ironBy similarity1
Metal bindingi90Manganese or ironBy similarity1
Metal bindingi172Manganese or ironBy similarity1
Metal bindingi176Manganese or ironBy similarity1

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
LigandIron, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutase [Mn/Fe] (EC:1.15.1.1)
Gene namesi
Name:sodB
Ordered Locus Names:RF_0741
OrganismiRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Taxonomic identifieri315456 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
Proteomesi
  • UP000008548 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002865021 – 209Superoxide dismutase [Mn/Fe]Add BLAST209

Interactioni

Protein-protein interaction databases

STRINGi315456.RF_0741.

Structurei

3D structure databases

ProteinModelPortaliQ4ULI1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105CK4. Bacteria.
COG0605. LUCA.
HOGENOMiHOG000013584.
KOiK04564.
OrthoDBiPOG0939004D.

Family and domain databases

InterProiView protein in InterPro
IPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
PfamiView protein in Pfam
PF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
PIRSFiPIRSF000349. SODismutase. 1 hit.
PRINTSiPR01703. MNSODISMTASE.
SUPFAMiSSF46609. SSF46609. 1 hit.
SSF54719. SSF54719. 1 hit.
PROSITEiView protein in PROSITE
PS00088. SOD_MN. 1 hit.

Sequencei

Sequence statusi: Complete.

Q4ULI1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTYCNKSNQT SYPFILPDLP YDKESFKPHF TPETFDYHHG KHHNAYVQNL
60 70 80 90 100
NNLLKDKEEL QKKDLEEIIE WSSQNSNAAI FNNAAQIWNH SFFWHSIKPQ
110 120 130 140 150
GGGKPSGKIL EQINKDFGSF EGFCEQFKQE AVGQFGSGWA WLVYHDNRLQ
160 170 180 190 200
IIKTANAGTP IANGMKPLLA CDVWEHAYYI DYRNKRPDYV DIFIKHMINW

KFVEDNLIK
Length:209
Mass (Da):24,465
Last modified:May 15, 2007 - v2
Checksum:iAACCBBD4D89F325C
GO

Sequence cautioni

The sequence AAY61592 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000053 Genomic DNA. Translation: AAY61592.1. Different initiation.
RefSeqiWP_041405318.1. NC_007109.1.

Genome annotation databases

EnsemblBacteriaiAAY61592; AAY61592; RF_0741.
KEGGirfe:RF_0741.
PATRICi17892134. VBIRicFel64634_0895.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000053 Genomic DNA. Translation: AAY61592.1. Different initiation.
RefSeqiWP_041405318.1. NC_007109.1.

3D structure databases

ProteinModelPortaliQ4ULI1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi315456.RF_0741.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAY61592; AAY61592; RF_0741.
KEGGirfe:RF_0741.
PATRICi17892134. VBIRicFel64634_0895.

Phylogenomic databases

eggNOGiENOG4105CK4. Bacteria.
COG0605. LUCA.
HOGENOMiHOG000013584.
KOiK04564.
OrthoDBiPOG0939004D.

Family and domain databases

InterProiView protein in InterPro
IPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
PfamiView protein in Pfam
PF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
PIRSFiPIRSF000349. SODismutase. 1 hit.
PRINTSiPR01703. MNSODISMTASE.
SUPFAMiSSF46609. SSF46609. 1 hit.
SSF54719. SSF54719. 1 hit.
PROSITEiView protein in PROSITE
PS00088. SOD_MN. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiSODF_RICFE
AccessioniPrimary (citable) accession number: Q4ULI1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: May 15, 2007
Last modified: February 15, 2017
This is version 71 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia felis (Rickettsia azadi)
    Rickettsia felis (strain URRWXCal2): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.