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Q4ULG0

- RF1_RICFE

UniProt

Q4ULG0 - RF1_RICFE

Protein

Peptide chain release factor 1

Gene

prfA

Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 59 (01 Oct 2014)
      Sequence version 1 (05 Jul 2005)
      Previous versions | rss
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    Functioni

    Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.UniRule annotation

    GO - Molecular functioni

    1. translation release factor activity, codon specific Source: UniProtKB-HAMAP

    Keywords - Biological processi

    Protein biosynthesis

    Enzyme and pathway databases

    BioCyciRFEL315456:GKEK-781-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Peptide chain release factor 1UniRule annotation
    Short name:
    RF-1UniRule annotation
    Gene namesi
    Name:prfAUniRule annotation
    Ordered Locus Names:RF_0762
    OrganismiRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
    Taxonomic identifieri315456 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
    ProteomesiUP000008548: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 355355Peptide chain release factor 1PRO_0000263340Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei233 – 2331N5-methylglutamineUniRule annotation

    Post-translational modificationi

    Methylated by PrmC. Methylation increases the termination efficiency of RF1.UniRule annotation

    Keywords - PTMi

    Methylation

    Interactioni

    Protein-protein interaction databases

    STRINGi315456.RF_0762.

    Structurei

    3D structure databases

    ProteinModelPortaliQ4ULG0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the prokaryotic/mitochondrial release factor family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0216.
    HOGENOMiHOG000074815.
    KOiK02835.
    OMAiYGQLKFE.
    OrthoDBiEOG6TN48J.

    Family and domain databases

    Gene3Di3.30.160.20. 1 hit.
    HAMAPiMF_00093. Rel_fac_1.
    InterProiIPR014720. dsRNA-bd_dom.
    IPR005139. PCRF.
    IPR000352. Pep_chain_release_fac_I_II.
    IPR004373. PrfA.
    [Graphical view]
    PfamiPF03462. PCRF. 1 hit.
    PF00472. RF-1. 1 hit.
    [Graphical view]
    SMARTiSM00937. PCRF. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00019. prfA. 1 hit.
    PROSITEiPS00745. RF_PROK_I. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q4ULG0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSFSDNLAKI LDKYENLGKK LSSGIMGDEF VKASKEYAEL EDVVAKIKEY    50
    NKAKSELEEA NNFKLEVGLD NATLEMIEDE IHTLENSLPK LERAVKIALL 100
    PKDDADSKSA IIEVRAGSGG EEAALFAAVL FNMYQRYAEL KGWRFEILAI 150
    SDTGIGGYKE ASASIKGKDV FSKLKFESGV HRVQRVPETE SQGRIHTSAA 200
    TVAVLPEAEE VDIKIEDKDL RIDTYRASGA GGQHVNTTDS AVRITHIPTG 250
    ITVALQDEKS QHKNKAKALK ILRARIYEEE RRKKEQERAD SRRGQVGSGD 300
    RSERIRTYNF PQGRVSDHRI NLTLYKIDEV VKNGQLDEFV EALIADDEAK 350
    KLSEI 355
    Length:355
    Mass (Da):39,658
    Last modified:July 5, 2005 - v1
    Checksum:iD71DD1AB9CE903A1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000053 Genomic DNA. Translation: AAY61613.1.
    RefSeqiWP_011271091.1. NC_007109.1.
    YP_246778.1. NC_007109.1.

    Genome annotation databases

    EnsemblBacteriaiAAY61613; AAY61613; RF_0762.
    GeneIDi3400829.
    KEGGirfe:RF_0762.
    PATRICi17892184. VBIRicFel64634_0920.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000053 Genomic DNA. Translation: AAY61613.1 .
    RefSeqi WP_011271091.1. NC_007109.1.
    YP_246778.1. NC_007109.1.

    3D structure databases

    ProteinModelPortali Q4ULG0.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 315456.RF_0762.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAY61613 ; AAY61613 ; RF_0762 .
    GeneIDi 3400829.
    KEGGi rfe:RF_0762.
    PATRICi 17892184. VBIRicFel64634_0920.

    Phylogenomic databases

    eggNOGi COG0216.
    HOGENOMi HOG000074815.
    KOi K02835.
    OMAi YGQLKFE.
    OrthoDBi EOG6TN48J.

    Enzyme and pathway databases

    BioCyci RFEL315456:GKEK-781-MONOMER.

    Family and domain databases

    Gene3Di 3.30.160.20. 1 hit.
    HAMAPi MF_00093. Rel_fac_1.
    InterProi IPR014720. dsRNA-bd_dom.
    IPR005139. PCRF.
    IPR000352. Pep_chain_release_fac_I_II.
    IPR004373. PrfA.
    [Graphical view ]
    Pfami PF03462. PCRF. 1 hit.
    PF00472. RF-1. 1 hit.
    [Graphical view ]
    SMARTi SM00937. PCRF. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00019. prfA. 1 hit.
    PROSITEi PS00745. RF_PROK_I. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
      Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
      PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC VR-1525 / URRWXCal2.

    Entry informationi

    Entry nameiRF1_RICFE
    AccessioniPrimary (citable) accession number: Q4ULG0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 12, 2006
    Last sequence update: July 5, 2005
    Last modified: October 1, 2014
    This is version 59 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Rickettsia felis (Rickettsia azadi)
      Rickettsia felis (strain URRWXCal2): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3