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Protein

Transcriptional regulator MraZ

Gene

mraZ

Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. sequence-specific DNA binding transcription factor activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciRFEL315456:GKEK-930-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Transcriptional regulator MraZ
Gene namesi
Name:mraZUniRule annotation
Ordered Locus Names:RF_0905
OrganismiRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Taxonomic identifieri315456 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
ProteomesiUP000008548: Chromosome

Subcellular locationi

Cytoplasmnucleoid UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
  2. nucleoid Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 149149Transcriptional regulator MraZPRO_0000230107Add
BLAST

Interactioni

Subunit structurei

Forms oligomers.UniRule annotation

Protein-protein interaction databases

STRINGi315456.RF_0905.

Structurei

3D structure databases

ProteinModelPortaliQ4UL17.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini7 – 5448SpoVT-AbrB 1PROSITE-ProRule annotationAdd
BLAST
Domaini83 – 12644SpoVT-AbrB 2PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the MraZ family.UniRule annotation
Contains 2 SpoVT-AbrB domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiCOG2001.
HOGENOMiHOG000283909.
KOiK03925.
OMAiGRTFQIW.
OrthoDBiEOG6G4W1C.

Family and domain databases

HAMAPiMF_01008. MraZ.
InterProiIPR003444. MraZ.
IPR020603. MraZ_dom.
[Graphical view]
PfamiPF02381. MraZ. 1 hit.
[Graphical view]
ProDomiPD006745. MraZ. 1 hit.
[Graphical view] [Entries sharing at least one domain]
PROSITEiPS51740. SPOVT_ABRB. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4UL17-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNVFLSKYVN GVDKKSRVSV PANYRAVLGK ELFNGVIAYP SIRNDCIEVC
60 70 80 90 100
GISHIEKLRQ MIETLDPYSE ERDAFETMIF GEAVQLSFDG EGRVILPQSL
110 120 130 140
MKHAGIEEQA CFVGKGVIFE IWQPQNFEKY LNSAQKIAHE KRLTLRNAN
Length:149
Mass (Da):16,927
Last modified:July 5, 2005 - v1
Checksum:iC66047D3142F2126
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000053 Genomic DNA. Translation: AAY61756.1.
RefSeqiWP_011271231.1. NC_007109.1.
YP_246921.1. NC_007109.1.

Genome annotation databases

EnsemblBacteriaiAAY61756; AAY61756; RF_0905.
GeneIDi3401571.
KEGGirfe:RF_0905.
PATRICi17892533. VBIRicFel64634_1088.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000053 Genomic DNA. Translation: AAY61756.1.
RefSeqiWP_011271231.1. NC_007109.1.
YP_246921.1. NC_007109.1.

3D structure databases

ProteinModelPortaliQ4UL17.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi315456.RF_0905.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAY61756; AAY61756; RF_0905.
GeneIDi3401571.
KEGGirfe:RF_0905.
PATRICi17892533. VBIRicFel64634_1088.

Phylogenomic databases

eggNOGiCOG2001.
HOGENOMiHOG000283909.
KOiK03925.
OMAiGRTFQIW.
OrthoDBiEOG6G4W1C.

Enzyme and pathway databases

BioCyciRFEL315456:GKEK-930-MONOMER.

Family and domain databases

HAMAPiMF_01008. MraZ.
InterProiIPR003444. MraZ.
IPR020603. MraZ_dom.
[Graphical view]
PfamiPF02381. MraZ. 1 hit.
[Graphical view]
ProDomiPD006745. MraZ. 1 hit.
[Graphical view] [Entries sharing at least one domain]
PROSITEiPS51740. SPOVT_ABRB. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
    Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
    PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-1525 / URRWXCal2.

Entry informationi

Entry nameiMRAZ_RICFE
AccessioniPrimary (citable) accession number: Q4UL17
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: July 5, 2005
Last modified: February 4, 2015
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia felis (Rickettsia azadi)
    Rickettsia felis (strain URRWXCal2): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.