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Q4UKW3

- SECD_RICFE

UniProt

Q4UKW3 - SECD_RICFE

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Protein
Protein translocase subunit SecD
Gene
secD, RF_0959
Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA By similarity.UniRule annotation

GO - Molecular functioni

  1. P-P-bond-hydrolysis-driven protein transmembrane transporter activity Source: InterPro

GO - Biological processi

  1. intracellular protein transmembrane transport Source: UniProtKB-HAMAP
  2. protein targeting Source: UniProtKB-HAMAP
  3. protein transport by the Sec complex Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Biological processi

Protein transport, Translocation, Transport

Enzyme and pathway databases

BioCyciRFEL315456:GKEK-988-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein translocase subunit SecD
Gene namesi
Name:secD
Ordered Locus Names:RF_0959
OrganismiRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Taxonomic identifieri315456 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
ProteomesiUP000008548: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei9 – 2921Helical; Reviewed prediction
Add
BLAST
Transmembranei361 – 38121Helical; Reviewed prediction
Add
BLAST
Transmembranei384 – 40421Helical; Reviewed prediction
Add
BLAST
Transmembranei406 – 42621Helical; Reviewed prediction
Add
BLAST
Transmembranei452 – 47423Helical; Reviewed prediction
Add
BLAST
Transmembranei486 – 50621Helical; Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. intracellular Source: GOC
  3. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 518518Protein translocase subunit SecDUniRule annotation
PRO_0000272635Add
BLAST

Interactioni

Subunit structurei

Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC By similarity.

Protein-protein interaction databases

STRINGi315456.RF_0959.

Structurei

3D structure databases

ProteinModelPortaliQ4UKW3.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0342.
HOGENOMiHOG000018636.
KOiK03072.
OMAiMATVFIE.
OrthoDBiEOG6N0HJT.

Family and domain databases

HAMAPiMF_01463_B. SecD_B.
InterProiIPR001036. Acrflvin-R.
IPR005791. SecD.
IPR022813. SecD/SecF_arch_bac.
IPR022645. SecD/SecF_bac.
IPR022646. SecD/SecF_CS.
[Graphical view]
PfamiPF07549. Sec_GG. 1 hit.
PF02355. SecD_SecF. 1 hit.
[Graphical view]
PRINTSiPR00702. ACRIFLAVINRP.
TIGRFAMsiTIGR00916. 2A0604s01. 1 hit.
TIGR01129. secD. 1 hit.

Sequencei

Sequence statusi: Complete.

Q4UKW3-1 [UniParc]FASTAAdd to Basket

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MQNLPKWKIF LSIICTVFAV ICALPNFMQV NSKFLPHDSV NLGLDLRGGA    50
HLLLDVDFDT YLNDSMENLA DTLRKNFRED KIGYKNLLVR QNSIQLEVRS 100
PEELKPLKKI INKIDPEIIA EVNENKIKLS YSESRLNDLL NKVVDQSIEI 150
VRMRVDSTGT KEPTLQKQGD KHILLQVPGE ENPSYLKNIL GKTAKLTFHL 200
VDENANIEEA VKGHVPVGSM LVKGDSESHR EYYVVIKKKV VLGGDQLTTA 250
SASFDQNSQA VVAFSFNNLG SKIFGEITKN NTGKRLAIVL DNKLLSAPTI 300
NGAIMGGSGI ITGNFTVESA NELALLLRAG SLPAPLKIIE ERSIGPSLGA 350
DSIESGKKAG LIGFIAVCIF MVWSYGVLGL FANIALSLAL LYILALLSLF 400
QATLTLPGIA GIILTMGMAV DANVLIYERI KEELHKGVSN LYAIRTGFES 450
AFATILDSNL TTLIVAFLLY IFGVGAIKGF AVALTIGIIS SMFSAIIITK 500
LLIDIWVKYF IPKKLGLV 518
Length:518
Mass (Da):56,608
Last modified:July 5, 2005 - v1
Checksum:i208C69B570F1EDFF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000053 Genomic DNA. Translation: AAY61810.1.
RefSeqiWP_011271282.1. NC_007109.1.
YP_246975.1. NC_007109.1.

Genome annotation databases

EnsemblBacteriaiAAY61810; AAY61810; RF_0959.
GeneIDi3400967.
KEGGirfe:RF_0959.
PATRICi17892665. VBIRicFel64634_1150.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000053 Genomic DNA. Translation: AAY61810.1 .
RefSeqi WP_011271282.1. NC_007109.1.
YP_246975.1. NC_007109.1.

3D structure databases

ProteinModelPortali Q4UKW3.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 315456.RF_0959.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAY61810 ; AAY61810 ; RF_0959 .
GeneIDi 3400967.
KEGGi rfe:RF_0959.
PATRICi 17892665. VBIRicFel64634_1150.

Phylogenomic databases

eggNOGi COG0342.
HOGENOMi HOG000018636.
KOi K03072.
OMAi MATVFIE.
OrthoDBi EOG6N0HJT.

Enzyme and pathway databases

BioCyci RFEL315456:GKEK-988-MONOMER.

Family and domain databases

HAMAPi MF_01463_B. SecD_B.
InterProi IPR001036. Acrflvin-R.
IPR005791. SecD.
IPR022813. SecD/SecF_arch_bac.
IPR022645. SecD/SecF_bac.
IPR022646. SecD/SecF_CS.
[Graphical view ]
Pfami PF07549. Sec_GG. 1 hit.
PF02355. SecD_SecF. 1 hit.
[Graphical view ]
PRINTSi PR00702. ACRIFLAVINRP.
TIGRFAMsi TIGR00916. 2A0604s01. 1 hit.
TIGR01129. secD. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
    Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
    PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-1525 / URRWXCal2.

Entry informationi

Entry nameiSECD_RICFE
AccessioniPrimary (citable) accession number: Q4UKW3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 23, 2007
Last sequence update: July 5, 2005
Last modified: September 3, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia felis (Rickettsia azadi)
    Rickettsia felis (strain URRWXCal2): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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