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Q4UKW3 (SECD_RICFE) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein translocase subunit SecD
Gene names
Name:secD
Ordered Locus Names:RF_0959
OrganismRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) [Complete proteome] [HAMAP]
Taxonomic identifier315456 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group

Protein attributes

Sequence length518 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA By similarity. HAMAP-Rule MF_01463

Subunit structure

Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC By similarity.

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01463.

Sequence similarities

Belongs to the SecD/SecF family. SecD subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 518518Protein translocase subunit SecD HAMAP-Rule MF_01463
PRO_0000272635

Regions

Transmembrane9 – 2921Helical; Potential
Transmembrane361 – 38121Helical; Potential
Transmembrane384 – 40421Helical; Potential
Transmembrane406 – 42621Helical; Potential
Transmembrane452 – 47423Helical; Potential
Transmembrane486 – 50621Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q4UKW3 [UniParc].

Last modified July 5, 2005. Version 1.
Checksum: 208C69B570F1EDFF

FASTA51856,608
        10         20         30         40         50         60 
MQNLPKWKIF LSIICTVFAV ICALPNFMQV NSKFLPHDSV NLGLDLRGGA HLLLDVDFDT 

        70         80         90        100        110        120 
YLNDSMENLA DTLRKNFRED KIGYKNLLVR QNSIQLEVRS PEELKPLKKI INKIDPEIIA 

       130        140        150        160        170        180 
EVNENKIKLS YSESRLNDLL NKVVDQSIEI VRMRVDSTGT KEPTLQKQGD KHILLQVPGE 

       190        200        210        220        230        240 
ENPSYLKNIL GKTAKLTFHL VDENANIEEA VKGHVPVGSM LVKGDSESHR EYYVVIKKKV 

       250        260        270        280        290        300 
VLGGDQLTTA SASFDQNSQA VVAFSFNNLG SKIFGEITKN NTGKRLAIVL DNKLLSAPTI 

       310        320        330        340        350        360 
NGAIMGGSGI ITGNFTVESA NELALLLRAG SLPAPLKIIE ERSIGPSLGA DSIESGKKAG 

       370        380        390        400        410        420 
LIGFIAVCIF MVWSYGVLGL FANIALSLAL LYILALLSLF QATLTLPGIA GIILTMGMAV 

       430        440        450        460        470        480 
DANVLIYERI KEELHKGVSN LYAIRTGFES AFATILDSNL TTLIVAFLLY IFGVGAIKGF 

       490        500        510 
AVALTIGIIS SMFSAIIITK LLIDIWVKYF IPKKLGLV 

« Hide

References

[1]"The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-1525 / URRWXCal2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000053 Genomic DNA. Translation: AAY61810.1.
RefSeqYP_246975.1. NC_007109.1.

3D structure databases

ProteinModelPortalQ4UKW3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING315456.RF_0959.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAY61810; AAY61810; RF_0959.
GeneID3400967.
KEGGrfe:RF_0959.
PATRIC17892665. VBIRicFel64634_1150.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0342.
HOGENOMHOG000018636.
KOK03072.
OMAVNLWYGR.
OrthoDBEOG6N0HJT.
ProtClustDBPRK05812.

Enzyme and pathway databases

BioCycRFEL315456:GKEK-988-MONOMER.

Family and domain databases

HAMAPMF_01463_B. SecD_B.
InterProIPR001036. Acrflvin-R.
IPR005791. SecD.
IPR022813. SecD/SecF_arch_bac.
IPR022645. SecD/SecF_bac.
IPR022646. SecD/SecF_CS.
[Graphical view]
PfamPF07549. Sec_GG. 1 hit.
PF02355. SecD_SecF. 1 hit.
[Graphical view]
PRINTSPR00702. ACRIFLAVINRP.
TIGRFAMsTIGR00916. 2A0604s01. 1 hit.
TIGR01129. secD. 1 hit.
ProtoNetSearch...

Entry information

Entry nameSECD_RICFE
AccessionPrimary (citable) accession number: Q4UKW3
Entry history
Integrated into UniProtKB/Swiss-Prot: January 23, 2007
Last sequence update: July 5, 2005
Last modified: February 19, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia felis (Rickettsia azadi)

Rickettsia felis (strain URRWXCal2): entries and gene names