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Protein

Putative pterin-4-alpha-carbinolamine dehydratase

Gene

RF_0997

Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

(6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H2O.UniRule annotation

GO - Molecular functioni

  1. 4-alpha-hydroxytetrahydrobiopterin dehydratase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. tetrahydrobiopterin biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Enzyme and pathway databases

BioCyciRFEL315456:GKEK-1027-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative pterin-4-alpha-carbinolamine dehydrataseUniRule annotation (EC:4.2.1.96UniRule annotation)
Short name:
PHSUniRule annotation
Alternative name(s):
4-alpha-hydroxy-tetrahydropterin dehydrataseUniRule annotation
Pterin carbinolamine dehydrataseUniRule annotation
Short name:
PCDUniRule annotation
Gene namesi
Ordered Locus Names:RF_0997
OrganismiRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Taxonomic identifieri315456 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
ProteomesiUP000008548 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 110110Putative pterin-4-alpha-carbinolamine dehydratasePRO_0000231473Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi315456.RF_0997.

Family & Domainsi

Sequence similaritiesi

Belongs to the pterin-4-alpha-carbinolamine dehydratase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2154.
HOGENOMiHOG000007681.
KOiK01724.
OMAiILTEWGK.
OrthoDBiEOG6S52NH.

Family and domain databases

Gene3Di3.30.1360.20. 1 hit.
HAMAPiMF_00434. Pterin_4_alpha.
InterProiIPR001533. Trans/pterin_deHydtase.
[Graphical view]
PANTHERiPTHR12599. PTHR12599. 1 hit.
PfamiPF01329. Pterin_4a. 1 hit.
[Graphical view]
SUPFAMiSSF55248. SSF55248. 1 hit.

Sequencei

Sequence statusi: Complete.

Q4UKS5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTVLSEKKCI PCEGGIPPLE KKEIDKLLVQ LQSKWQVNEL GHLYKKYKFP
60 70 80 90 100
NFVKAMEFAN KITEIAEQEA HHPDLTISWG ACSVEIWTHK IDGLTESDFI
110
LAAKIESINS
Length:110
Mass (Da):12,512
Last modified:July 4, 2005 - v1
Checksum:i3F9E4FB1F2C7EC6C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000053 Genomic DNA. Translation: AAY61848.1.
RefSeqiYP_247013.1. NC_007109.1.

Genome annotation databases

EnsemblBacteriaiAAY61848; AAY61848; RF_0997.
KEGGirfe:RF_0997.
PATRICi17892755. VBIRicFel64634_1194.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000053 Genomic DNA. Translation: AAY61848.1.
RefSeqiYP_247013.1. NC_007109.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi315456.RF_0997.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAY61848; AAY61848; RF_0997.
KEGGirfe:RF_0997.
PATRICi17892755. VBIRicFel64634_1194.

Phylogenomic databases

eggNOGiCOG2154.
HOGENOMiHOG000007681.
KOiK01724.
OMAiILTEWGK.
OrthoDBiEOG6S52NH.

Enzyme and pathway databases

BioCyciRFEL315456:GKEK-1027-MONOMER.

Family and domain databases

Gene3Di3.30.1360.20. 1 hit.
HAMAPiMF_00434. Pterin_4_alpha.
InterProiIPR001533. Trans/pterin_deHydtase.
[Graphical view]
PANTHERiPTHR12599. PTHR12599. 1 hit.
PfamiPF01329. Pterin_4a. 1 hit.
[Graphical view]
SUPFAMiSSF55248. SSF55248. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
    Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
    PLoS Biol. 3:1-12(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-1525 / URRWXCal2.

Entry informationi

Entry nameiPHS_RICFE
AccessioniPrimary (citable) accession number: Q4UKS5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 3, 2006
Last sequence update: July 4, 2005
Last modified: March 31, 2015
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia felis (Rickettsia azadi)
    Rickettsia felis (strain URRWXCal2): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.