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Q4UKS5 (PHS_RICFE) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 48. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative pterin-4-alpha-carbinolamine dehydratase

Short name=PHS
EC=4.2.1.96
Alternative name(s):
4-alpha-hydroxy-tetrahydropterin dehydratase
Pterin carbinolamine dehydratase
Short name=PCD
Gene names
Ordered Locus Names:RF_0997
OrganismRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) [Complete proteome] [HAMAP]
Taxonomic identifier315456 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group

Protein attributes

Sequence length110 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H2O. HAMAP-Rule MF_00434

Sequence similarities

Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

Ontologies

Keywords
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtetrahydrobiopterin biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular_function4-alpha-hydroxytetrahydrobiopterin dehydratase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 110110Putative pterin-4-alpha-carbinolamine dehydratase HAMAP-Rule MF_00434
PRO_0000231473

Sequences

Sequence LengthMass (Da)Tools
Q4UKS5 [UniParc].

Last modified July 5, 2005. Version 1.
Checksum: 3F9E4FB1F2C7EC6C

FASTA11012,512
        10         20         30         40         50         60 
MTVLSEKKCI PCEGGIPPLE KKEIDKLLVQ LQSKWQVNEL GHLYKKYKFP NFVKAMEFAN 

        70         80         90        100        110 
KITEIAEQEA HHPDLTISWG ACSVEIWTHK IDGLTESDFI LAAKIESINS 

« Hide

References

[1]"The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-1525 / URRWXCal2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000053 Genomic DNA. Translation: AAY61848.1.
RefSeqYP_247013.1. NC_007109.1.

3D structure databases

ProteinModelPortalQ4UKS5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING315456.RF_0997.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAY61848; AAY61848; RF_0997.
GeneID3401006.
KEGGrfe:RF_0997.
PATRIC17892755. VBIRicFel64634_1194.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2154.
HOGENOMHOG000007681.
KOK01724.
OMAILTEWGK.
OrthoDBEOG6S52NH.
ProtClustDBCLSK937597.

Enzyme and pathway databases

BioCycRFEL315456:GKEK-1027-MONOMER.

Family and domain databases

Gene3D3.30.1360.20. 1 hit.
HAMAPMF_00434. Pterin_4_alpha.
InterProIPR001533. Trans/pterin_deHydtase.
[Graphical view]
PANTHERPTHR12599. PTHR12599. 1 hit.
PfamPF01329. Pterin_4a. 1 hit.
[Graphical view]
SUPFAMSSF55248. SSF55248. 1 hit.
ProtoNetSearch...

Entry information

Entry namePHS_RICFE
AccessionPrimary (citable) accession number: Q4UKS5
Entry history
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: July 5, 2005
Last modified: February 19, 2014
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia felis (Rickettsia azadi)

Rickettsia felis (strain URRWXCal2): entries and gene names