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Q4UKR6 (UCRI_RICFE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ubiquinol-cytochrome c reductase iron-sulfur subunit

EC=1.10.2.2
Alternative name(s):
Rieske iron-sulfur protein
Short name=RISP
Gene names
Name:petA
Ordered Locus Names:RF_1010
OrganismRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) [Complete proteome] [HAMAP]
Taxonomic identifier315456 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group

Protein attributes

Sequence length177 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.

Catalytic activity

Quinol + 2 ferricytochrome c = quinone + 2 ferrocytochrome c + 2 H+.

Cofactor

Binds 1 2Fe-2S cluster per subunit By similarity.

Subunit structure

The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

Subcellular location

Cell membrane; Single-pass membrane protein Potential.

Miscellaneous

The Rieske protein is a high potential 2Fe-2S protein.

Sequence similarities

Contains 1 Rieske domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 177177Ubiquinol-cytochrome c reductase iron-sulfur subunit
PRO_0000286643

Regions

Transmembrane18 – 3821Helical; Potential
Domain88 – 17588Rieske

Sites

Metal binding1201Iron-sulfur (2Fe-2S) By similarity
Metal binding1221Iron-sulfur (2Fe-2S); via pros nitrogen By similarity
Metal binding1391Iron-sulfur (2Fe-2S) By similarity
Metal binding1421Iron-sulfur (2Fe-2S); via pros nitrogen By similarity

Amino acid modifications

Disulfide bond125 ↔ 141 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q4UKR6 [UniParc].

Last modified July 5, 2005. Version 1.
Checksum: 8F500C77E8FD743D

FASTA17719,228
        10         20         30         40         50         60 
MSDTEDNKNK QTTRRDFMVL TASSVAAVGA VCTLWPLVDS LNPSADVLAL SSIEVDLSNI 

        70         80         90        100        110        120 
AVGQTVTVKW QGKPVFITNR TPDKIAEARA VKMSELIDPE TDEARVKAGH DNWLVTIGIC 

       130        140        150        160        170 
THLGCVPLAN QGEYDGWFCP CHGSQYDSSG RVRRGPAPLN LAVPPYTFIS DKKIRIG 

« Hide

References

[1]"The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-1525 / URRWXCal2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000053 Genomic DNA. Translation: AAY61861.1.
RefSeqYP_247026.1. NC_007109.1.

3D structure databases

ProteinModelPortalQ4UKR6.
SMRQ4UKR6. Positions 118-163.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING315456.RF_1010.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAY61861; AAY61861; RF_1010.
GeneID3401020.
KEGGrfe:RF_1010.
PATRIC17892785. VBIRicFel64634_1208.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0723.
HOGENOMHOG000255193.
KOK00411.
OMAAVGLCTH.
OrthoDBEOG6RNQD9.
ProtClustDBCLSK870834.

Enzyme and pathway databases

BioCycRFEL315456:GKEK-1042-MONOMER.

Family and domain databases

Gene3D2.102.10.10. 1 hit.
InterProIPR017941. Rieske_2Fe-2S.
IPR014349. Rieske_Fe-S_prot.
IPR005805. Rieske_Fe-S_prot_C.
IPR006311. TAT_signal.
IPR019546. TAT_signal_bac_arc.
IPR019470. Ubiq_cytC_Rdtase_Fe-S_su_TAT.
IPR006317. Ubiquinol_cyt_c_Rdtase_Fe-S-su.
[Graphical view]
PANTHERPTHR10134. PTHR10134. 1 hit.
PfamPF00355. Rieske. 1 hit.
PF10399. UCR_Fe-S_N. 1 hit.
[Graphical view]
PRINTSPR00162. RIESKE.
SUPFAMSSF50022. SSF50022. 1 hit.
TIGRFAMsTIGR01416. Rieske_proteo. 1 hit.
TIGR01409. TAT_signal_seq. 1 hit.
PROSITEPS51296. RIESKE. 1 hit.
PS51318. TAT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUCRI_RICFE
AccessionPrimary (citable) accession number: Q4UKR6
Entry history
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: July 5, 2005
Last modified: April 16, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia felis (Rickettsia azadi)

Rickettsia felis (strain URRWXCal2): entries and gene names