Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q4UKQ2

- CTAA_RICFE

UniProt

Q4UKQ2 - CTAA_RICFE

Protein

Heme A synthase

Gene

ctaA

Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 57 (01 Oct 2014)
      Sequence version 1 (05 Jul 2005)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei316 – 3161SubstrateUniRule annotation

    GO - Molecular functioni

    1. oxidoreductase activity, acting on the CH-CH group of donors Source: InterPro

    GO - Biological processi

    1. heme a biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Heme biosynthesis

    Enzyme and pathway databases

    BioCyciRFEL315456:GKEK-1056-MONOMER.
    UniPathwayiUPA00269; UER00713.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Heme A synthaseUniRule annotation (EC:1.3.-.-UniRule annotation)
    Short name:
    HASUniRule annotation
    Alternative name(s):
    Cytochrome aa3-controlling proteinUniRule annotation
    Gene namesi
    Name:ctaAUniRule annotation
    Synonyms:coxW
    Ordered Locus Names:RF_1024
    OrganismiRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
    Taxonomic identifieri315456 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
    ProteomesiUP000008548: Chromosome

    Subcellular locationi

    Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 337337Heme A synthasePRO_0000349076Add
    BLAST

    Interactioni

    Subunit structurei

    Interacts with CtaB.UniRule annotation

    Protein-protein interaction databases

    STRINGi315456.RF_1024.

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei6 – 2621HelicalUniRule annotationAdd
    BLAST
    Transmembranei93 – 11321HelicalUniRule annotationAdd
    BLAST
    Transmembranei118 – 13821HelicalUniRule annotationAdd
    BLAST
    Transmembranei154 – 17421HelicalUniRule annotationAdd
    BLAST
    Transmembranei192 – 21221HelicalUniRule annotationAdd
    BLAST
    Transmembranei258 – 27821HelicalUniRule annotationAdd
    BLAST
    Transmembranei285 – 30521HelicalUniRule annotationAdd
    BLAST
    Transmembranei308 – 32821HelicalUniRule annotationAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the COX15/CtaA family. Type 2 subfamily.UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG1612.
    HOGENOMiHOG000214943.
    KOiK02259.
    OMAiLSMVTWK.
    OrthoDBiEOG6KMB6V.

    Family and domain databases

    HAMAPiMF_01665. HemeA_synth_type2.
    InterProiIPR003780. COX15/CtaA_fam.
    IPR023754. HemeA_Synthase_type2.
    [Graphical view]
    PfamiPF02628. COX15-CtaA. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q4UKQ2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQKSLITKWL FISCIMVIAM IVIGGITRLT GSGLSIVEWR PVTGILPPFS    50
    FESWQAEFAK YKAFPEYNSI NYGMTLSQFK FIYLLEFVHR LLGRITALIY 100
    IVPLIYFYFK DVIKNRDILP YIIALLLFCV QGFMGWYMVK SGLLNSPSVS 150
    HFRLAFHLII AVIIYHILFY QLIKNRCDIL LIPSQTDLKL PLIFSGIAIT 200
    VIYVQIFLGA MVAGLDAGLI YNSFPLMGDN FIPMEIKDNF FNLANLHDPV 250
    FIQFIHRLGG YSVFLVVVVL VICLLKIEHP KLNKIAYFLM IALLMQISTG 300
    IITLLYSVPI IIASIHQLFA IILLSIIIWC YFIIKTS 337
    Length:337
    Mass (Da):38,545
    Last modified:July 5, 2005 - v1
    Checksum:i60535EF3B04FF76F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000053 Genomic DNA. Translation: AAY61875.1.
    RefSeqiYP_247040.1. NC_007109.1.

    Genome annotation databases

    EnsemblBacteriaiAAY61875; AAY61875; RF_1024.
    GeneIDi3400134.
    KEGGirfe:RF_1024.
    PATRICi17892823. VBIRicFel64634_1227.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000053 Genomic DNA. Translation: AAY61875.1 .
    RefSeqi YP_247040.1. NC_007109.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 315456.RF_1024.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAY61875 ; AAY61875 ; RF_1024 .
    GeneIDi 3400134.
    KEGGi rfe:RF_1024.
    PATRICi 17892823. VBIRicFel64634_1227.

    Phylogenomic databases

    eggNOGi COG1612.
    HOGENOMi HOG000214943.
    KOi K02259.
    OMAi LSMVTWK.
    OrthoDBi EOG6KMB6V.

    Enzyme and pathway databases

    UniPathwayi UPA00269 ; UER00713 .
    BioCyci RFEL315456:GKEK-1056-MONOMER.

    Family and domain databases

    HAMAPi MF_01665. HemeA_synth_type2.
    InterProi IPR003780. COX15/CtaA_fam.
    IPR023754. HemeA_Synthase_type2.
    [Graphical view ]
    Pfami PF02628. COX15-CtaA. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
      Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
      PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC VR-1525 / URRWXCal2.

    Entry informationi

    Entry nameiCTAA_RICFE
    AccessioniPrimary (citable) accession number: Q4UKQ2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 2, 2008
    Last sequence update: July 5, 2005
    Last modified: October 1, 2014
    This is version 57 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. Rickettsia felis (Rickettsia azadi)
      Rickettsia felis (strain URRWXCal2): entries and gene names
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3