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Q4UKM7 (EFP_RICFE) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Elongation factor P

Short name=EF-P
Gene names
Name:efp
Ordered Locus Names:RF_1049
OrganismRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) [Complete proteome] [HAMAP]
Taxonomic identifier315456 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group

Protein attributes

Sequence length188 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase By similarity. HAMAP-Rule MF_00141

Pathway

Protein biosynthesis; polypeptide chain elongation. HAMAP-Rule MF_00141

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00141.

Sequence similarities

Belongs to the elongation factor P family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   Molecular functionElongation factor
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processpeptide biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functiontranslation elongation factor activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 188188Elongation factor P HAMAP-Rule MF_00141
PRO_0000274854

Sequences

Sequence LengthMass (Da)Tools
Q4UKM7 [UniParc].

Last modified July 5, 2005. Version 1.
Checksum: DB7DCFF8B8128CC0

FASTA18821,504
        10         20         30         40         50         60 
MKISANSIRT GNILVYNNDL WVVSKTPEHT QPGKGGAYVQ VEMKNLKTGT KRNERFSSSD 

        70         80         90        100        110        120 
YLEKAELEQK DYQFLYFEGD DLVLMDTKHF EQINVPKEIL EEKLPFLTEN MIVKVEFYNE 

       130        140        150        160        170        180 
KPLNIELPPT VILEINETDP VIKGATATAS YKPAILENGI KVKVPQYLEV GEKIVVKTDD 


MTYVERAK 

« Hide

References

[1]"The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-1525 / URRWXCal2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000053 Genomic DNA. Translation: AAY61900.1.
RefSeqYP_247065.1. NC_007109.1.

3D structure databases

ProteinModelPortalQ4UKM7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING315456.RF_1049.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAY61900; AAY61900; RF_1049.
GeneID3400159.
KEGGrfe:RF_1049.
PATRIC17892880. VBIRicFel64634_1255.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0231.
HOGENOMHOG000010048.
KOK02356.
OMAAGNVIMH.
OrthoDBEOG6JQH6Q.
ProtClustDBPRK00529.

Enzyme and pathway databases

BioCycRFEL315456:GKEK-1081-MONOMER.
UniPathwayUPA00345.

Family and domain databases

Gene3D2.30.30.30. 1 hit.
2.40.50.140. 2 hits.
HAMAPMF_00141. EF_P.
InterProIPR015365. Elong-fact-P_C.
IPR012340. NA-bd_OB-fold.
IPR014722. Rib_L2_dom2.
IPR020599. Transl_elong_fac_P/YeiP.
IPR013185. Transl_elong_KOW-like.
IPR001059. Transl_elong_P/YeiP_cen.
IPR013852. Transl_elong_P/YeiP_CS.
IPR011768. Transl_elongation_fac_P.
IPR008991. Translation_prot_SH3-like.
[Graphical view]
PfamPF01132. EFP. 1 hit.
PF08207. EFP_N. 1 hit.
PF09285. Elong-fact-P_C. 1 hit.
[Graphical view]
PIRSFPIRSF005901. EF-P. 1 hit.
SMARTSM00841. Elong-fact-P_C. 1 hit.
[Graphical view]
SUPFAMSSF50104. SSF50104. 1 hit.
SSF50249. SSF50249. 2 hits.
TIGRFAMsTIGR00038. efp. 1 hit.
PROSITEPS01275. EFP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameEFP_RICFE
AccessionPrimary (citable) accession number: Q4UKM7
Entry history
Integrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: July 5, 2005
Last modified: February 19, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia felis (Rickettsia azadi)

Rickettsia felis (strain URRWXCal2): entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways