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Q4UKM7

- EFP_RICFE

UniProt

Q4UKM7 - EFP_RICFE

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Protein

Elongation factor P

Gene

efp

Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. translation elongation factor activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. peptide biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Elongation factor

Keywords - Biological processi

Protein biosynthesis

Enzyme and pathway databases

BioCyciRFEL315456:GKEK-1081-MONOMER.
UniPathwayiUPA00345.

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor PUniRule annotation
Short name:
EF-PUniRule annotation
Gene namesi
Name:efpUniRule annotation
Ordered Locus Names:RF_1049
OrganismiRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Taxonomic identifieri315456 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
ProteomesiUP000008548: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 188188Elongation factor PPRO_0000274854Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi315456.RF_1049.

Structurei

3D structure databases

ProteinModelPortaliQ4UKM7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the elongation factor P family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0231.
HOGENOMiHOG000010048.
KOiK02356.
OMAiLYKMRFT.
OrthoDBiEOG6JQH6Q.

Family and domain databases

Gene3Di2.30.30.30. 1 hit.
2.40.50.140. 2 hits.
HAMAPiMF_00141. EF_P.
InterProiIPR015365. Elong-fact-P_C.
IPR012340. NA-bd_OB-fold.
IPR014722. Rib_L2_dom2.
IPR020599. Transl_elong_fac_P/YeiP.
IPR013185. Transl_elong_KOW-like.
IPR001059. Transl_elong_P/YeiP_cen.
IPR013852. Transl_elong_P/YeiP_CS.
IPR011768. Transl_elongation_fac_P.
IPR008991. Translation_prot_SH3-like.
[Graphical view]
PfamiPF01132. EFP. 1 hit.
PF08207. EFP_N. 1 hit.
PF09285. Elong-fact-P_C. 1 hit.
[Graphical view]
PIRSFiPIRSF005901. EF-P. 1 hit.
SMARTiSM00841. Elong-fact-P_C. 1 hit.
[Graphical view]
SUPFAMiSSF50104. SSF50104. 1 hit.
SSF50249. SSF50249. 2 hits.
TIGRFAMsiTIGR00038. efp. 1 hit.
PROSITEiPS01275. EFP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4UKM7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKISANSIRT GNILVYNNDL WVVSKTPEHT QPGKGGAYVQ VEMKNLKTGT
60 70 80 90 100
KRNERFSSSD YLEKAELEQK DYQFLYFEGD DLVLMDTKHF EQINVPKEIL
110 120 130 140 150
EEKLPFLTEN MIVKVEFYNE KPLNIELPPT VILEINETDP VIKGATATAS
160 170 180
YKPAILENGI KVKVPQYLEV GEKIVVKTDD MTYVERAK
Length:188
Mass (Da):21,504
Last modified:July 5, 2005 - v1
Checksum:iDB7DCFF8B8128CC0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000053 Genomic DNA. Translation: AAY61900.1.
RefSeqiYP_247065.1. NC_007109.1.

Genome annotation databases

EnsemblBacteriaiAAY61900; AAY61900; RF_1049.
GeneIDi3400159.
KEGGirfe:RF_1049.
PATRICi17892880. VBIRicFel64634_1255.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000053 Genomic DNA. Translation: AAY61900.1 .
RefSeqi YP_247065.1. NC_007109.1.

3D structure databases

ProteinModelPortali Q4UKM7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 315456.RF_1049.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAY61900 ; AAY61900 ; RF_1049 .
GeneIDi 3400159.
KEGGi rfe:RF_1049.
PATRICi 17892880. VBIRicFel64634_1255.

Phylogenomic databases

eggNOGi COG0231.
HOGENOMi HOG000010048.
KOi K02356.
OMAi LYKMRFT.
OrthoDBi EOG6JQH6Q.

Enzyme and pathway databases

UniPathwayi UPA00345 .
BioCyci RFEL315456:GKEK-1081-MONOMER.

Family and domain databases

Gene3Di 2.30.30.30. 1 hit.
2.40.50.140. 2 hits.
HAMAPi MF_00141. EF_P.
InterProi IPR015365. Elong-fact-P_C.
IPR012340. NA-bd_OB-fold.
IPR014722. Rib_L2_dom2.
IPR020599. Transl_elong_fac_P/YeiP.
IPR013185. Transl_elong_KOW-like.
IPR001059. Transl_elong_P/YeiP_cen.
IPR013852. Transl_elong_P/YeiP_CS.
IPR011768. Transl_elongation_fac_P.
IPR008991. Translation_prot_SH3-like.
[Graphical view ]
Pfami PF01132. EFP. 1 hit.
PF08207. EFP_N. 1 hit.
PF09285. Elong-fact-P_C. 1 hit.
[Graphical view ]
PIRSFi PIRSF005901. EF-P. 1 hit.
SMARTi SM00841. Elong-fact-P_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50104. SSF50104. 1 hit.
SSF50249. SSF50249. 2 hits.
TIGRFAMsi TIGR00038. efp. 1 hit.
PROSITEi PS01275. EFP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
    Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
    PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-1525 / URRWXCal2.

Entry informationi

Entry nameiEFP_RICFE
AccessioniPrimary (citable) accession number: Q4UKM7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: July 5, 2005
Last modified: October 29, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. Rickettsia felis (Rickettsia azadi)
    Rickettsia felis (strain URRWXCal2): entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3