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Protein

Elongation factor P

Gene

efp

Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.UniRule annotation

Pathwayi: polypeptide chain elongation

This protein is involved in the pathway polypeptide chain elongation, which is part of Protein biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway polypeptide chain elongation and in Protein biosynthesis.

GO - Molecular functioni

Keywordsi

Molecular functionElongation factor
Biological processProtein biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00345

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor PUniRule annotation
Short name:
EF-PUniRule annotation
Gene namesi
Name:efpUniRule annotation
Ordered Locus Names:RF_1049
OrganismiRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Taxonomic identifieri315456 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
Proteomesi
  • UP000008548 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002748541 – 188Elongation factor PAdd BLAST188

Interactioni

Protein-protein interaction databases

STRINGi315456.RF_1049

Structurei

3D structure databases

ProteinModelPortaliQ4UKM7
SMRiQ4UKM7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the elongation factor P family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DRH Bacteria
COG0231 LUCA
HOGENOMiHOG000010048
KOiK02356
OMAiFMDNEDY
OrthoDBiPOG091H028W

Family and domain databases

CDDicd04470 S1_EF-P_repeat_1, 1 hit
cd05794 S1_EF-P_repeat_2, 1 hit
Gene3Di2.30.30.30, 1 hit
HAMAPiMF_00141 EF_P, 1 hit
InterProiView protein in InterPro
IPR015365 Elong-fact-P_C
IPR012340 NA-bd_OB-fold
IPR014722 Rib_L2_dom2
IPR020599 Transl_elong_fac_P/YeiP
IPR013185 Transl_elong_KOW-like
IPR001059 Transl_elong_P/YeiP_cen
IPR013852 Transl_elong_P/YeiP_CS
IPR011768 Transl_elongation_fac_P
IPR008991 Translation_prot_SH3-like_sf
PANTHERiPTHR30053 PTHR30053, 1 hit
PfamiView protein in Pfam
PF01132 EFP, 1 hit
PF08207 EFP_N, 1 hit
PF09285 Elong-fact-P_C, 1 hit
PIRSFiPIRSF005901 EF-P, 1 hit
SMARTiView protein in SMART
SM01185 EFP, 1 hit
SM00841 Elong-fact-P_C, 1 hit
SUPFAMiSSF50104 SSF50104, 1 hit
SSF50249 SSF50249, 2 hits
TIGRFAMsiTIGR00038 efp, 1 hit
PROSITEiView protein in PROSITE
PS01275 EFP, 1 hit

Sequencei

Sequence statusi: Complete.

Q4UKM7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKISANSIRT GNILVYNNDL WVVSKTPEHT QPGKGGAYVQ VEMKNLKTGT
60 70 80 90 100
KRNERFSSSD YLEKAELEQK DYQFLYFEGD DLVLMDTKHF EQINVPKEIL
110 120 130 140 150
EEKLPFLTEN MIVKVEFYNE KPLNIELPPT VILEINETDP VIKGATATAS
160 170 180
YKPAILENGI KVKVPQYLEV GEKIVVKTDD MTYVERAK
Length:188
Mass (Da):21,504
Last modified:July 5, 2005 - v1
Checksum:iDB7DCFF8B8128CC0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000053 Genomic DNA Translation: AAY61900.1
RefSeqiWP_011271364.1, NC_007109.1

Genome annotation databases

EnsemblBacteriaiAAY61900; AAY61900; RF_1049
KEGGirfe:RF_1049

Similar proteinsi

Entry informationi

Entry nameiEFP_RICFE
AccessioniPrimary (citable) accession number: Q4UKM7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: July 5, 2005
Last modified: March 28, 2018
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health