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Q4UKK0 (COX3_RICFE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome aa3 subunit 3
Cytochrome c oxidase polypeptide III
Gene names
Name:ctaE
Synonyms:coxC
Ordered Locus Names:RF_1076
OrganismRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) [Complete proteome] [HAMAP]
Taxonomic identifier315456 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group

Protein attributes

Sequence length278 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Keywords
   Cellular componentCell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processaerobic electron transport chain

Inferred from electronic annotation. Source: InterPro

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functioncytochrome-c oxidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 278278Probable cytochrome c oxidase subunit 3
PRO_0000280890

Regions

Transmembrane21 – 4121Helical; Potential
Transmembrane46 – 6621Helical; Potential
Transmembrane89 – 10921Helical; Potential
Transmembrane174 – 19421Helical; Potential
Transmembrane212 – 23221Helical; Potential
Transmembrane256 – 27621Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q4UKK0 [UniParc].

Last modified July 5, 2005. Version 1.
Checksum: 7CF5B3F4E7BDCAB9

FASTA27831,505
        10         20         30         40         50         60 
MNPNSHPITK SHLFHIVDPS PWPVLTSFAL LLLVIGGVSF MHGYKFNIYI LSAGVISVGY 

        70         80         90        100        110        120 
CLYSWWRDVV KEGIVEHQHT SPVRKGLQIG MALFILTEIV FFGVFFASFF KSSLSPVGLL 

       130        140        150        160        170        180 
DGVWVVKQGI WPPPTIKTFD PFDIPFINTL ILLLSGTTVT WAHYALEEKN QKDCVTALAL 

       190        200        210        220        230        240 
TILLGIFFTT MQAYEYYHAA FKFTDGIYAS NFYLATGFHG AHVIIGTIFL IVCYFRAKRG 

       250        260        270 
DFTTEGNGHL GFEFAAWYWH FVDVVWLFLF TFVYIFGS 

« Hide

References

[1]"The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-1525 / URRWXCal2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000053 Genomic DNA. Translation: AAY61927.1.
RefSeqYP_247092.1. NC_007109.1.

3D structure databases

ProteinModelPortalQ4UKK0.
SMRQ4UKK0. Positions 9-278.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING315456.RF_1076.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAY61927; AAY61927; RF_1076.
GeneID3400186.
KEGGrfe:RF_1076.
PATRIC17892954. VBIRicFel64634_1292.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1845.
HOGENOMHOG000264954.
KOK02276.
OMAFFWAFYH.
OrthoDBEOG6V7BK2.
ProtClustDBCLSK870788.

Enzyme and pathway databases

BioCycRFEL315456:GKEK-1108-MONOMER.

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_RICFE
AccessionPrimary (citable) accession number: Q4UKK0
Entry history
Integrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: July 5, 2005
Last modified: April 16, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia felis (Rickettsia azadi)

Rickettsia felis (strain URRWXCal2): entries and gene names