ID RRF_RICFE Reviewed; 186 AA. AC Q4UKF3; DT 13-SEP-2005, integrated into UniProtKB/Swiss-Prot. DT 05-JUL-2005, sequence version 1. DT 27-MAR-2024, entry version 91. DE RecName: Full=Ribosome-recycling factor {ECO:0000255|HAMAP-Rule:MF_00040}; DE Short=RRF {ECO:0000255|HAMAP-Rule:MF_00040}; DE AltName: Full=Ribosome-releasing factor {ECO:0000255|HAMAP-Rule:MF_00040}; GN Name=frr {ECO:0000255|HAMAP-Rule:MF_00040}; OrderedLocusNames=RF_1127; OS Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi). OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rickettsiales; OC Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group. OX NCBI_TaxID=315456; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC VR-1525 / URRWXCal2; RX PubMed=15984913; DOI=10.1371/journal.pbio.0030248; RA Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., RA Parinello H., Claverie J.-M., Raoult D.; RT "The genome sequence of Rickettsia felis identifies the first putative RT conjugative plasmid in an obligate intracellular parasite."; RL PLoS Biol. 3:1-12(2005). CC -!- FUNCTION: Responsible for the release of ribosomes from messenger RNA CC at the termination of protein biosynthesis. May increase the efficiency CC of translation by recycling ribosomes from one round of translation to CC another. {ECO:0000255|HAMAP-Rule:MF_00040}. CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00040}. CC -!- SIMILARITY: Belongs to the RRF family. {ECO:0000255|HAMAP- CC Rule:MF_00040}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP000053; AAY61978.1; -; Genomic_DNA. DR AlphaFoldDB; Q4UKF3; -. DR SMR; Q4UKF3; -. DR STRING; 315456.RF_1127; -. DR KEGG; rfe:RF_1127; -. DR eggNOG; COG0233; Bacteria. DR HOGENOM; CLU_073981_2_1_5; -. DR OrthoDB; 9804006at2; -. DR Proteomes; UP000008548; Chromosome. DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0006415; P:translational termination; IEA:UniProtKB-UniRule. DR CDD; cd00520; RRF; 1. DR Gene3D; 3.30.1360.40; -; 1. DR Gene3D; 1.10.132.20; Ribosome-recycling factor; 1. DR HAMAP; MF_00040; RRF; 1. DR InterPro; IPR002661; Ribosome_recyc_fac. DR InterPro; IPR023584; Ribosome_recyc_fac_dom. DR InterPro; IPR036191; RRF_sf. DR NCBIfam; TIGR00496; frr; 1. DR PANTHER; PTHR20982:SF3; MITOCHONDRIAL RIBOSOME RECYCLING FACTOR; 1. DR PANTHER; PTHR20982; RIBOSOME RECYCLING FACTOR; 1. DR Pfam; PF01765; RRF; 1. DR SUPFAM; SSF55194; Ribosome recycling factor, RRF; 1. PE 3: Inferred from homology; KW Cytoplasm; Protein biosynthesis. FT CHAIN 1..186 FT /note="Ribosome-recycling factor" FT /id="PRO_0000167528" SQ SEQUENCE 186 AA; 20864 MW; 761574C075F3137D CRC64; MDTETLKKNL QEKMDKALKV LDHELKGLRT GRASVNLLDS VTVEAYGSKM PLSQVASLST PDARTINVQV WDKSMVSSVE KGITIANLGL TPATDGQLIR LPIPALTEER RKELVKLAHK YGEDTKISLR NIRRDGNEEL KKLEKDNIIA KDEHHSLSEQ VQKLTDDYSS KVDSAIKQKE QEIMTV //