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Q4UKF1

- GATA_RICFE

UniProt

Q4UKF1 - GATA_RICFE

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Protein

Glutamyl-tRNA(Gln) amidotransferase subunit A

Gene
gatA, RF_1129
Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) By similarity.UniRule annotation

Catalytic activityi

ATP + L-glutamyl-tRNA(Gln) + L-glutamine = ADP + phosphate + L-glutaminyl-tRNA(Gln) + L-glutamate.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei78 – 781Charge relay system By similarity
Active sitei158 – 1581Charge relay system By similarity
Active sitei182 – 1821Acyl-ester intermediate By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. translation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciRFEL315456:GKEK-1162-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamyl-tRNA(Gln) amidotransferase subunit A (EC:6.3.5.7)
Short name:
Glu-ADT subunit A
Gene namesi
Name:gatA
Ordered Locus Names:RF_1129
OrganismiRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Taxonomic identifieri315456 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
ProteomesiUP000008548: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 493493Glutamyl-tRNA(Gln) amidotransferase subunit AUniRule annotationPRO_0000241149Add
BLAST

Interactioni

Subunit structurei

Heterotrimer of A, B and C subunits By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi315456.RF_1129.

Structurei

3D structure databases

ProteinModelPortaliQ4UKF1.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0154.
HOGENOMiHOG000116699.
KOiK02433.
OMAiYDILLAY.
OrthoDBiEOG61P6R9.

Family and domain databases

Gene3Di3.90.1300.10. 1 hit.
HAMAPiMF_00120. GatA.
InterProiIPR000120. Amidase.
IPR020556. Amidase_CS.
IPR023631. Amidase_dom.
IPR004412. GatA.
[Graphical view]
PANTHERiPTHR11895. PTHR11895. 1 hit.
PfamiPF01425. Amidase. 1 hit.
[Graphical view]
SUPFAMiSSF75304. SSF75304. 1 hit.
TIGRFAMsiTIGR00132. gatA. 1 hit.
PROSITEiPS00571. AMIDASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4UKF1-1 [UniParc]FASTAAdd to Basket

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MTELNKLTVA DSVKGLKNKD FTSKELVNAH IKQIEKHKNL NAYVTETFDL    50
ALKQAEAADQ NYAQNQPQTL EGIPFAAKDL FCTKGIRTTA CSNILKNFIP 100
NYESSVTQNI FDKGGVMLGK TNMDEFAMGS ANITSCFGNV ISPWKANDDN 150
ADLVPGGSSG GSAAAVSGFM ASAALGSDTG GSVRQPASFT GLVGFKPTYG 200
RCSRYGMVSF ASSLDQAGIF TRSVLDSSIM LEAMMGFDEK DSTSIKAEVP 250
ELQSAIGSSM KNMKIGVPLS LGEGGIIEPD IMKMWQDTIE LLKNAGAEIV 300
DITLPHAKYG VAVYYVIAPA EASSNLSRYD GVRYGLRVER ENMTLDEMYE 350
MTRSAGFGEE VKRRIMIGTY VLSSSCMDAY YLKAQKVRRL VANDFNNAFA 400
KVDAILLPAA PTEAFKIGEK QNDPTIMYLN DLFTIPASLA GLPCASVPAG 450
LSARGLPLGM QIIGKQLDEY NVLKVASTIE SGVKHIKFEP KGF 493
Length:493
Mass (Da):53,180
Last modified:July 5, 2005 - v1
Checksum:i1BA841879A33C182
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000053 Genomic DNA. Translation: AAY61980.1.
RefSeqiYP_247145.1. NC_007109.1.

Genome annotation databases

EnsemblBacteriaiAAY61980; AAY61980; RF_1129.
GeneIDi3401426.
KEGGirfe:RF_1129.
PATRICi17893100. VBIRicFel64634_1364.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000053 Genomic DNA. Translation: AAY61980.1 .
RefSeqi YP_247145.1. NC_007109.1.

3D structure databases

ProteinModelPortali Q4UKF1.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 315456.RF_1129.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAY61980 ; AAY61980 ; RF_1129 .
GeneIDi 3401426.
KEGGi rfe:RF_1129.
PATRICi 17893100. VBIRicFel64634_1364.

Phylogenomic databases

eggNOGi COG0154.
HOGENOMi HOG000116699.
KOi K02433.
OMAi YDILLAY.
OrthoDBi EOG61P6R9.

Enzyme and pathway databases

BioCyci RFEL315456:GKEK-1162-MONOMER.

Family and domain databases

Gene3Di 3.90.1300.10. 1 hit.
HAMAPi MF_00120. GatA.
InterProi IPR000120. Amidase.
IPR020556. Amidase_CS.
IPR023631. Amidase_dom.
IPR004412. GatA.
[Graphical view ]
PANTHERi PTHR11895. PTHR11895. 1 hit.
Pfami PF01425. Amidase. 1 hit.
[Graphical view ]
SUPFAMi SSF75304. SSF75304. 1 hit.
TIGRFAMsi TIGR00132. gatA. 1 hit.
PROSITEi PS00571. AMIDASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
    Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
    PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-1525 / URRWXCal2.

Entry informationi

Entry nameiGATA_RICFE
AccessioniPrimary (citable) accession number: Q4UKF1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: July 5, 2005
Last modified: May 14, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia felis (Rickettsia azadi)
    Rickettsia felis (strain URRWXCal2): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi