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Q4UKD5 (RPOC_RICFE) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
DNA-directed RNA polymerase subunit beta'

Short name=RNAP subunit beta'
EC=2.7.7.6
Alternative name(s):
RNA polymerase subunit beta'
Transcriptase subunit beta'
Gene names
Name:rpoC
Ordered Locus Names:RF_1145
OrganismRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) [Complete proteome] [HAMAP]
Taxonomic identifier315456 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group

Protein attributes

Sequence length1372 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates By similarity. HAMAP-Rule MF_01322

Catalytic activity

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). HAMAP-Rule MF_01322

Subunit structure

The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription By similarity.

Sequence similarities

Belongs to the RNA polymerase beta' chain family.

Ontologies

Keywords
   Biological processTranscription
   Cellular componentDNA-directed RNA polymerase
   Molecular functionNucleotidyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtranscription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionDNA binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

DNA-directed RNA polymerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 13721372DNA-directed RNA polymerase subunit beta' HAMAP-Rule MF_01322
PRO_0000225573

Sequences

Sequence LengthMass (Da)Tools
Q4UKD5 [UniParc].

Last modified July 5, 2005. Version 1.
Checksum: 864E04C0B485E8CB

FASTA1,372153,405
        10         20         30         40         50         60 
MSVVNFYGQL SNTQQFDQIR INIASPDQVR SWSFGEVTKP ETINYRTFKP EKDGLFCARI 

        70         80         90        100        110        120 
FGPVKDYECL CGKYKRMKNR GITCEKCGVE VTVSRVRRER MGHIELAAPV AHIWFLKSLP 

       130        140        150        160        170        180 
SRISTLLDMT MRDVEKILYF ENYVVVDPGL SILQKGELLT EEELQKAKDK YGEDAFTASI 

       190        200        210        220        230        240 
GAEVIQQMLK EIDFLKLKQE LYEELQTTSS EVKKKKLVKR LKLVEDFLES ENKPEWMIMD 

       250        260        270        280        290        300 
VLPVIPPEIR PLVMLDGGRF ATSDLNELYR RVINRNNRLK KLIESKAPDI IVRNEKRMLQ 

       310        320        330        340        350        360 
EAVDALFDNG RRGRAAKNAN KRPFKSLSDM LKGKQGRFRQ NLLGKRVDYS GRSVIVVGSE 

       370        380        390        400        410        420 
LKLHQCGLPK KMALELFKPF IYSKLELYGI ATTIKAAKRM VEAEKPEVWD VLEEVIREHP 

       430        440        450        460        470        480 
VLLNRAPTLH RLGIQAFEPL LIEGKAIQLY PLVCAAFNAD FDGDQMAVHI PLSIEAQLEA 

       490        500        510        520        530        540 
RVFMMSTNNI LSPANGRPII VPDKDIVLGL YYLTLAFDNE VGEGMMFSDL AEMEHALYNK 

       550        560        570        580        590        600 
FITIHTKIKY RRNQLNAEGK MVPVIIDTTY GRLMVGELLP SNPNIEFKFI NKQLTKKDIS 

       610        620        630        640        650        660 
LVIDLVYRHC GQKATVIFAD QLMKLGFKYA CSSGISFGMD DMVVPESKST HINETQLEIK 

       670        680        690        700        710        720 
EFEQQYSNGL ITYGEKYNKV VDAWSRCTDR VANDMMKEIA TPPVSDDPNH QKINAIYMMA 

       730        740        750        760        770        780 
ISGARGSFQQ IKQLGGMRGL MTKSNGQIIQ TPIISNFKEG LTEFECFNSA NGMRKGQIDT 

       790        800        810        820        830        840 
ALKTASSGYL TRKLVDVAQD CIITEKDCGT DKGIEVKSVI EGGEVIVPLA EKILGRTAAI 

       850        860        870        880        890        900 
DIFHPVTNDL ILNKGELINE AKLEQIESAG LDRIMIKSVL TCESTTGICS ICYGRDLATG 

       910        920        930        940        950        960 
TLVSEGEAIG VIAAQSIGEP GTQLTMRTFH IGGAATKGAE VSSVEASYDA KVKIISRNVV 

       970        980        990       1000       1010       1020 
INSEERKIVM SRNCELLLLD NNGNEKARHK IPYGARLLVD DGDMVIKTQK LAEWDPYTIP 

      1030       1040       1050       1060       1070       1080 
IITEKSGKVL FKDMVEGISI RDVTDEATGI PSKVIIESKQ YSRGAELRPR IQLLDAKGEV 

      1090       1100       1110       1120       1130       1140 
IALSNGLEAR YYLPVGAVLS VEDGVQISVG DIIARIPKES TTTKDITGGL PRVAELVEAR 

      1150       1160       1170       1180       1190       1200 
RPKDHAVIAE IDGRVEFGKD YKSKRRIIIH PIDETMSIEY MVPKGKHVVV NEGDFVKKGD 

      1210       1220       1230       1240       1250       1260 
LLIDGNPVLQ DILKVMGVEV LANYIVKEVQ AVYRLQGVKI DDKHIEVIIR QMLQKVEITD 

      1270       1280       1290       1300       1310       1320 
SGGTTLLAGE KIDRHEFEEI NEKAIKNGLK PAEAQLILQG ITKASLQTRS FISAASFQET 

      1330       1340       1350       1360       1370 
TRVLTEAAIA GKIDKLRGLK ENVIVGRLVP AGTGYFMDKM RKAAVKLDEE NV 

« Hide

References

[1]"The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-1525 / URRWXCal2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000053 Genomic DNA. Translation: AAY61996.1.
RefSeqYP_247161.1. NC_007109.1.

3D structure databases

ProteinModelPortalQ4UKD5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING315456.RF_1145.

Proteomic databases

PRIDEQ4UKD5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAY61996; AAY61996; RF_1145.
GeneID3401442.
KEGGrfe:RF_1145.
PATRIC17893134. VBIRicFel64634_1381.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0086.
HOGENOMHOG000218386.
KOK03046.
OMAKIPNTEH.
OrthoDBEOG6M9DS6.
ProtClustDBPRK00566.

Enzyme and pathway databases

BioCycRFEL315456:GKEK-1178-MONOMER.

Family and domain databases

HAMAPMF_01322. RNApol_bact_RpoC.
InterProIPR012754. DNA-dir_RpoC_beta_prime.
IPR000722. RNA_pol_asu.
IPR006592. RNA_pol_N.
IPR007080. RNA_pol_Rpb1_1.
IPR007066. RNA_pol_Rpb1_3.
IPR007083. RNA_pol_Rpb1_4.
IPR007081. RNA_pol_Rpb1_5.
[Graphical view]
PfamPF04997. RNA_pol_Rpb1_1. 1 hit.
PF00623. RNA_pol_Rpb1_2. 1 hit.
PF04983. RNA_pol_Rpb1_3. 1 hit.
PF05000. RNA_pol_Rpb1_4. 1 hit.
PF04998. RNA_pol_Rpb1_5. 1 hit.
[Graphical view]
SMARTSM00663. RPOLA_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR02386. rpoC_TIGR. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRPOC_RICFE
AccessionPrimary (citable) accession number: Q4UKD5
Entry history
Integrated into UniProtKB/Swiss-Prot: March 7, 2006
Last sequence update: July 5, 2005
Last modified: February 19, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia felis (Rickettsia azadi)

Rickettsia felis (strain URRWXCal2): entries and gene names