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Q4UKC1

- DHSC_RICFE

UniProt

Q4UKC1 - DHSC_RICFE

Protein

Succinate dehydrogenase cytochrome b556 subunit

Gene

sdhC

Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 63 (01 Oct 2014)
      Sequence version 1 (05 Jul 2005)
      Previous versions | rss
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    Functioni

    Membrane-anchoring subunit of succinate dehydrogenase (SDH).By similarity

    Cofactori

    Heme group. The heme is bound between the two transmembrane subunits By similarity.By similarity

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi83 – 831Iron (heme axial ligand); shared with second transmembrane subunitBy similarity

    GO - Molecular functioni

    1. electron carrier activity Source: InterPro
    2. metal ion binding Source: UniProtKB-KW
    3. succinate dehydrogenase activity Source: InterPro

    GO - Biological processi

    1. tricarboxylic acid cycle Source: UniProtKB-UniPathway

    Keywords - Biological processi

    Electron transport, Transport, Tricarboxylic acid cycle

    Keywords - Ligandi

    Heme, Iron, Metal-binding

    Enzyme and pathway databases

    BioCyciRETL1328306-WGS:GSTH-3985-MONOMER.
    RFEL315456:GKEK-1197-MONOMER.
    UniPathwayiUPA00223.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Succinate dehydrogenase cytochrome b556 subunit
    Short name:
    Cytochrome b-556
    Gene namesi
    Name:sdhC
    Ordered Locus Names:RF_1163
    OrganismiRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
    Taxonomic identifieri315456 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
    ProteomesiUP000008548: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell
    3. succinate dehydrogenase complex Source: InterPro

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 124124Succinate dehydrogenase cytochrome b556 subunitPRO_0000281051Add
    BLAST

    Interactioni

    Subunit structurei

    Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers By similarity.By similarity

    Protein-protein interaction databases

    STRINGi315456.RF_1163.

    Structurei

    3D structure databases

    ProteinModelPortaliQ4UKC1.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 2929CytoplasmicBy similarityAdd
    BLAST
    Topological domaini56 – 6712PeriplasmicBy similarityAdd
    BLAST
    Topological domaini89 – 10315CytoplasmicBy similarityAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei30 – 5526HelicalBy similarityAdd
    BLAST
    Transmembranei68 – 8821HelicalBy similarityAdd
    BLAST
    Transmembranei104 – 12421HelicalBy similarityAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the cytochrome b560 family.Curated

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG2009.
    HOGENOMiHOG000160253.
    KOiK00241.
    OMAiWALMHHM.
    OrthoDBiEOG647V36.

    Family and domain databases

    InterProiIPR018495. Succ_DH_cyt_bsu_CS.
    IPR014314. Succ_DH_cytb556.
    IPR014361. Succ_DH_cytb560.
    IPR000701. Succ_DH_Fumarate_Rdtase_TM-su.
    [Graphical view]
    PfamiPF01127. Sdh_cyt. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000178. SDH_cyt_b560. 1 hit.
    TIGRFAMsiTIGR02970. succ_dehyd_cytB. 1 hit.
    PROSITEiPS01000. SDH_CYT_1. 1 hit.
    PS01001. SDH_CYT_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q4UKC1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTKTKQEIYN KRPTSPHLSI YKLQISSTLS ILHRMTGVAL FFAVSILAWW    50
    LILSKYDNNY LQFANCCIIK ICLVAVSYAW FYHLCNGIRH LFWDIGYGFS 100
    IKAVNITGWC VVVCSILLTM LLWV 124
    Length:124
    Mass (Da):14,358
    Last modified:July 5, 2005 - v1
    Checksum:iA756A3E50CE104D3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000053 Genomic DNA. Translation: AAY62014.1.
    RefSeqiYP_247179.1. NC_007109.1.

    Genome annotation databases

    EnsemblBacteriaiAAY62014; AAY62014; RF_1163.
    GeneIDi3401461.
    KEGGirfe:RF_1163.
    PATRICi17893174. VBIRicFel64634_1400.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000053 Genomic DNA. Translation: AAY62014.1 .
    RefSeqi YP_247179.1. NC_007109.1.

    3D structure databases

    ProteinModelPortali Q4UKC1.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 315456.RF_1163.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAY62014 ; AAY62014 ; RF_1163 .
    GeneIDi 3401461.
    KEGGi rfe:RF_1163.
    PATRICi 17893174. VBIRicFel64634_1400.

    Phylogenomic databases

    eggNOGi COG2009.
    HOGENOMi HOG000160253.
    KOi K00241.
    OMAi WALMHHM.
    OrthoDBi EOG647V36.

    Enzyme and pathway databases

    UniPathwayi UPA00223 .
    BioCyci RETL1328306-WGS:GSTH-3985-MONOMER.
    RFEL315456:GKEK-1197-MONOMER.

    Family and domain databases

    InterProi IPR018495. Succ_DH_cyt_bsu_CS.
    IPR014314. Succ_DH_cytb556.
    IPR014361. Succ_DH_cytb560.
    IPR000701. Succ_DH_Fumarate_Rdtase_TM-su.
    [Graphical view ]
    Pfami PF01127. Sdh_cyt. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000178. SDH_cyt_b560. 1 hit.
    TIGRFAMsi TIGR02970. succ_dehyd_cytB. 1 hit.
    PROSITEi PS01000. SDH_CYT_1. 1 hit.
    PS01001. SDH_CYT_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
      Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
      PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC VR-1525 / URRWXCal2.

    Entry informationi

    Entry nameiDHSC_RICFE
    AccessioniPrimary (citable) accession number: Q4UKC1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 20, 2007
    Last sequence update: July 5, 2005
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. Rickettsia felis (Rickettsia azadi)
      Rickettsia felis (strain URRWXCal2): entries and gene names
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3