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Q4UKC1

- DHSC_RICFE

UniProt

Q4UKC1 - DHSC_RICFE

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Protein

Succinate dehydrogenase cytochrome b556 subunit

Gene
sdhC, RF_1163
Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Membrane-anchoring subunit of succinate dehydrogenase (SDH) By similarity.

Cofactori

Heme group. The heme is bound between the two transmembrane subunits By similarity.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi83 – 831Iron (heme axial ligand); shared with second transmembrane subunit By similarity

GO - Molecular functioni

  1. electron carrier activity Source: InterPro
  2. metal ion binding Source: UniProtKB-KW
  3. succinate dehydrogenase activity Source: InterPro

GO - Biological processi

  1. tricarboxylic acid cycle Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Biological processi

Electron transport, Transport, Tricarboxylic acid cycle

Keywords - Ligandi

Heme, Iron, Metal-binding

Enzyme and pathway databases

BioCyciRETL1328306-WGS:GSTH-3985-MONOMER.
RFEL315456:GKEK-1197-MONOMER.
UniPathwayiUPA00223.

Names & Taxonomyi

Protein namesi
Recommended name:
Succinate dehydrogenase cytochrome b556 subunit
Short name:
Cytochrome b-556
Gene namesi
Name:sdhC
Ordered Locus Names:RF_1163
OrganismiRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Taxonomic identifieri315456 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
ProteomesiUP000008548: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2929Cytoplasmic By similarityAdd
BLAST
Transmembranei30 – 5526Helical; By similarityAdd
BLAST
Topological domaini56 – 6712Periplasmic By similarityAdd
BLAST
Transmembranei68 – 8821Helical; By similarityAdd
BLAST
Topological domaini89 – 10315Cytoplasmic By similarityAdd
BLAST
Transmembranei104 – 12421Helical; By similarityAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
  3. succinate dehydrogenase complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 124124Succinate dehydrogenase cytochrome b556 subunitPRO_0000281051Add
BLAST

Interactioni

Subunit structurei

Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers By similarity.

Protein-protein interaction databases

STRINGi315456.RF_1163.

Structurei

3D structure databases

ProteinModelPortaliQ4UKC1.

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome b560 family.

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG2009.
HOGENOMiHOG000160253.
KOiK00241.
OMAiWALMHHM.
OrthoDBiEOG647V36.

Family and domain databases

InterProiIPR018495. Succ_DH_cyt_bsu_CS.
IPR014314. Succ_DH_cytb556.
IPR014361. Succ_DH_cytb560.
IPR000701. Succ_DH_Fumarate_Rdtase_TM-su.
[Graphical view]
PfamiPF01127. Sdh_cyt. 1 hit.
[Graphical view]
PIRSFiPIRSF000178. SDH_cyt_b560. 1 hit.
TIGRFAMsiTIGR02970. succ_dehyd_cytB. 1 hit.
PROSITEiPS01000. SDH_CYT_1. 1 hit.
PS01001. SDH_CYT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4UKC1-1 [UniParc]FASTAAdd to Basket

« Hide

MTKTKQEIYN KRPTSPHLSI YKLQISSTLS ILHRMTGVAL FFAVSILAWW    50
LILSKYDNNY LQFANCCIIK ICLVAVSYAW FYHLCNGIRH LFWDIGYGFS 100
IKAVNITGWC VVVCSILLTM LLWV 124
Length:124
Mass (Da):14,358
Last modified:July 5, 2005 - v1
Checksum:iA756A3E50CE104D3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000053 Genomic DNA. Translation: AAY62014.1.
RefSeqiYP_247179.1. NC_007109.1.

Genome annotation databases

EnsemblBacteriaiAAY62014; AAY62014; RF_1163.
GeneIDi3401461.
KEGGirfe:RF_1163.
PATRICi17893174. VBIRicFel64634_1400.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000053 Genomic DNA. Translation: AAY62014.1 .
RefSeqi YP_247179.1. NC_007109.1.

3D structure databases

ProteinModelPortali Q4UKC1.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 315456.RF_1163.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAY62014 ; AAY62014 ; RF_1163 .
GeneIDi 3401461.
KEGGi rfe:RF_1163.
PATRICi 17893174. VBIRicFel64634_1400.

Phylogenomic databases

eggNOGi COG2009.
HOGENOMi HOG000160253.
KOi K00241.
OMAi WALMHHM.
OrthoDBi EOG647V36.

Enzyme and pathway databases

UniPathwayi UPA00223 .
BioCyci RETL1328306-WGS:GSTH-3985-MONOMER.
RFEL315456:GKEK-1197-MONOMER.

Family and domain databases

InterProi IPR018495. Succ_DH_cyt_bsu_CS.
IPR014314. Succ_DH_cytb556.
IPR014361. Succ_DH_cytb560.
IPR000701. Succ_DH_Fumarate_Rdtase_TM-su.
[Graphical view ]
Pfami PF01127. Sdh_cyt. 1 hit.
[Graphical view ]
PIRSFi PIRSF000178. SDH_cyt_b560. 1 hit.
TIGRFAMsi TIGR02970. succ_dehyd_cytB. 1 hit.
PROSITEi PS01000. SDH_CYT_1. 1 hit.
PS01001. SDH_CYT_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
    Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
    PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-1525 / URRWXCal2.

Entry informationi

Entry nameiDHSC_RICFE
AccessioniPrimary (citable) accession number: Q4UKC1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: July 5, 2005
Last modified: July 9, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. Rickettsia felis (Rickettsia azadi)
    Rickettsia felis (strain URRWXCal2): entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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