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Protein

Succinate dehydrogenase cytochrome b556 subunit

Gene

sdhC

Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Membrane-anchoring subunit of succinate dehydrogenase (SDH).By similarity

Cofactori

hemeBy similarityNote: The heme is bound between the two transmembrane subunits.By similarity

Pathway: tricarboxylic acid cycle

This protein is involved in the pathway tricarboxylic acid cycle, which is part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi83 – 831Iron (heme axial ligand); shared with second transmembrane subunitBy similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Electron transport, Transport, Tricarboxylic acid cycle

Keywords - Ligandi

Heme, Iron, Metal-binding

Enzyme and pathway databases

BioCyciRETL1328306-WGS:GSTH-3985-MONOMER.
RFEL315456:GKEK-1197-MONOMER.
UniPathwayiUPA00223.

Names & Taxonomyi

Protein namesi
Recommended name:
Succinate dehydrogenase cytochrome b556 subunit
Short name:
Cytochrome b-556
Gene namesi
Name:sdhC
Ordered Locus Names:RF_1163
OrganismiRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Taxonomic identifieri315456 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
ProteomesiUP000008548 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2929CytoplasmicBy similarityAdd
BLAST
Transmembranei30 – 5526HelicalBy similarityAdd
BLAST
Topological domaini56 – 6712PeriplasmicBy similarityAdd
BLAST
Transmembranei68 – 8821HelicalBy similarityAdd
BLAST
Topological domaini89 – 10315CytoplasmicBy similarityAdd
BLAST
Transmembranei104 – 12421HelicalBy similarityAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 124124Succinate dehydrogenase cytochrome b556 subunitPRO_0000281051Add
BLAST

Interactioni

Subunit structurei

Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers (By similarity).By similarity

Protein-protein interaction databases

STRINGi315456.RF_1163.

Structurei

3D structure databases

ProteinModelPortaliQ4UKC1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome b560 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG2009.
HOGENOMiHOG000160253.
KOiK00241.
OMAiWALMHHM.
OrthoDBiEOG647V36.

Family and domain databases

InterProiIPR018495. Succ_DH_cyt_bsu_CS.
IPR014314. Succ_DH_cytb556.
IPR000701. Succ_DH_Fumarate_Rdtase_TM-su.
[Graphical view]
PfamiPF01127. Sdh_cyt. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02970. succ_dehyd_cytB. 1 hit.
PROSITEiPS01000. SDH_CYT_1. 1 hit.
PS01001. SDH_CYT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4UKC1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKTKQEIYN KRPTSPHLSI YKLQISSTLS ILHRMTGVAL FFAVSILAWW
60 70 80 90 100
LILSKYDNNY LQFANCCIIK ICLVAVSYAW FYHLCNGIRH LFWDIGYGFS
110 120
IKAVNITGWC VVVCSILLTM LLWV
Length:124
Mass (Da):14,358
Last modified:July 5, 2005 - v1
Checksum:iA756A3E50CE104D3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000053 Genomic DNA. Translation: AAY62014.1.
RefSeqiWP_011271471.1. NC_007109.1.
YP_247179.1. NC_007109.1.

Genome annotation databases

EnsemblBacteriaiAAY62014; AAY62014; RF_1163.
KEGGirfe:RF_1163.
PATRICi17893174. VBIRicFel64634_1400.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000053 Genomic DNA. Translation: AAY62014.1.
RefSeqiWP_011271471.1. NC_007109.1.
YP_247179.1. NC_007109.1.

3D structure databases

ProteinModelPortaliQ4UKC1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi315456.RF_1163.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAY62014; AAY62014; RF_1163.
KEGGirfe:RF_1163.
PATRICi17893174. VBIRicFel64634_1400.

Phylogenomic databases

eggNOGiCOG2009.
HOGENOMiHOG000160253.
KOiK00241.
OMAiWALMHHM.
OrthoDBiEOG647V36.

Enzyme and pathway databases

UniPathwayiUPA00223.
BioCyciRETL1328306-WGS:GSTH-3985-MONOMER.
RFEL315456:GKEK-1197-MONOMER.

Family and domain databases

InterProiIPR018495. Succ_DH_cyt_bsu_CS.
IPR014314. Succ_DH_cytb556.
IPR000701. Succ_DH_Fumarate_Rdtase_TM-su.
[Graphical view]
PfamiPF01127. Sdh_cyt. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02970. succ_dehyd_cytB. 1 hit.
PROSITEiPS01000. SDH_CYT_1. 1 hit.
PS01001. SDH_CYT_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
    Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
    PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-1525 / URRWXCal2.

Entry informationi

Entry nameiDHSC_RICFE
AccessioniPrimary (citable) accession number: Q4UKC1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: July 5, 2005
Last modified: May 27, 2015
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. Rickettsia felis (Rickettsia azadi)
    Rickettsia felis (strain URRWXCal2): entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.