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Protein

Protein translocase subunit SecF

Gene

secF

Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transport, Translocation, Transport

Enzyme and pathway databases

BioCyciRFEL315456:GKEK-1213-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein translocase subunit SecF
Gene namesi
Name:secFUniRule annotation
Ordered Locus Names:RF_1179
OrganismiRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Taxonomic identifieri315456 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
Proteomesi
  • UP000008548 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei28 – 4821HelicalUniRule annotationAdd
BLAST
Transmembranei140 – 16021HelicalUniRule annotationAdd
BLAST
Transmembranei164 – 18421HelicalUniRule annotationAdd
BLAST
Transmembranei194 – 21421HelicalUniRule annotationAdd
BLAST
Transmembranei246 – 26621HelicalUniRule annotationAdd
BLAST
Transmembranei272 – 29221HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 308308Protein translocase subunit SecFPRO_0000272639Add
BLAST

Interactioni

Subunit structurei

Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.UniRule annotation

Protein-protein interaction databases

STRINGi315456.RF_1179.

Structurei

3D structure databases

ProteinModelPortaliQ4UKA5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SecD/SecF family. SecF subfamily.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4107RAB. Bacteria.
COG0341. LUCA.
HOGENOMiHOG000245916.
KOiK03074.
OMAiIDMNLEV.
OrthoDBiEOG676Z5R.

Family and domain databases

HAMAPiMF_01464_B. SecF_B.
InterProiIPR022813. SecD/SecF_arch_bac.
IPR022645. SecD/SecF_bac.
IPR022646. SecD/SecF_CS.
IPR005665. SecF_bac.
IPR000731. SSD.
[Graphical view]
PfamiPF07549. Sec_GG. 1 hit.
PF02355. SecD_SecF. 1 hit.
[Graphical view]
PRINTSiPR01755. SECFTRNLCASE.
TIGRFAMsiTIGR00916. 2A0604s01. 1 hit.
TIGR00966. 3a0501s07. 1 hit.
PROSITEiPS50156. SSD. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4UKA5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQIYPLRLLP NKIDFDFMNF KKVSYSFSII LSLISFIWIG IYKFNFGIDF
60 70 80 90 100
AGGIVIEVRL DQAPDLPKMR GVLGELGIGE VVLQNFGSER DLSIRFGSSS
110 120 130 140 150
EENLMKNIEL IKASLQSNFP YKFEYRKVDF VGPQVGRQLI EAGAMAMLFS
160 170 180 190 200
FLAIMVYIWV RFEWYFGLGI LIALVHDVIL ALGFMSMTKL DFNLSTIAAV
210 220 230 240 250
LTIIGYSVND SVVIYDRIRE NLRKYHKKNI TEIINLSINE TLSRTILTVI
260 270 280 290 300
TTLLANLALI LFGGEAIRSF SVLVFFGIIA GTYSSIFISA PILTMFANRK

FNKKVIER
Length:308
Mass (Da):34,945
Last modified:July 5, 2005 - v1
Checksum:i511569331687FC81
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000053 Genomic DNA. Translation: AAY62030.1.
RefSeqiWP_011271487.1. NC_007109.1.

Genome annotation databases

EnsemblBacteriaiAAY62030; AAY62030; RF_1179.
KEGGirfe:RF_1179.
PATRICi17893212. VBIRicFel64634_1419.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000053 Genomic DNA. Translation: AAY62030.1.
RefSeqiWP_011271487.1. NC_007109.1.

3D structure databases

ProteinModelPortaliQ4UKA5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi315456.RF_1179.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAY62030; AAY62030; RF_1179.
KEGGirfe:RF_1179.
PATRICi17893212. VBIRicFel64634_1419.

Phylogenomic databases

eggNOGiENOG4107RAB. Bacteria.
COG0341. LUCA.
HOGENOMiHOG000245916.
KOiK03074.
OMAiIDMNLEV.
OrthoDBiEOG676Z5R.

Enzyme and pathway databases

BioCyciRFEL315456:GKEK-1213-MONOMER.

Family and domain databases

HAMAPiMF_01464_B. SecF_B.
InterProiIPR022813. SecD/SecF_arch_bac.
IPR022645. SecD/SecF_bac.
IPR022646. SecD/SecF_CS.
IPR005665. SecF_bac.
IPR000731. SSD.
[Graphical view]
PfamiPF07549. Sec_GG. 1 hit.
PF02355. SecD_SecF. 1 hit.
[Graphical view]
PRINTSiPR01755. SECFTRNLCASE.
TIGRFAMsiTIGR00916. 2A0604s01. 1 hit.
TIGR00966. 3a0501s07. 1 hit.
PROSITEiPS50156. SSD. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
    Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
    PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-1525 / URRWXCal2.

Entry informationi

Entry nameiSECF_RICFE
AccessioniPrimary (citable) accession number: Q4UKA5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 23, 2007
Last sequence update: July 5, 2005
Last modified: December 9, 2015
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia felis (Rickettsia azadi)
    Rickettsia felis (strain URRWXCal2): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.