Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q4UK99 (HLYC_RICFE) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Hemolysin C
Gene names
Name:tlyC
Ordered Locus Names:RF_1185
OrganismRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) [Complete proteome] [HAMAP]
Taxonomic identifier315456 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group

Protein attributes

Sequence length299 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the UPF0053 family. Hemolysin C subfamily.

Contains 2 CBS domains.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 299299Hemolysin C
PRO_0000319031

Regions

Domain80 – 14263CBS 1
Domain145 – 20258CBS 2

Sequences

Sequence LengthMass (Da)Tools
Q4UK99 [UniParc].

Last modified July 5, 2005. Version 1.
Checksum: 1062D73CDC0A902D

FASTA29933,883
        10         20         30         40         50         60 
MLKSSKKEDS SKKNQNNKLI FTVRKLFSPI KNFFRKTKTP DNFFGVIKRL KINSQKMTLD 

        70         80         90        100        110        120 
ERNILANLLE LEDKTIEDIM VPRSDIAAIK LTTNLEELSE SIKLEVPHTR TLIYDGTLDN 

       130        140        150        160        170        180 
VVGFIHIKDL FKALATKQNG RLKKLIRKHI IAAPSMKLLD LLAKMRRERT HIAIVVDEYG 

       190        200        210        220        230        240 
GTDGLVTIED LIEEIVGRID DEHDQQLDSD NFKVINNSTI ISNARVEVEV LEEIIGEKLK 

       250        260        270        280        290 
NDDDEFDTIG GLVLTRVGSV PAIGTRIDIS ENIEIEVTDA TPRSLKQVKI RLKNGLNSK 

« Hide

References

[1]"The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], HEMOLYTIC ACTIVITY.
Strain: ATCC VR-1525 / URRWXCal2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000053 Genomic DNA. Translation: AAY62036.1.
RefSeqYP_247201.1. NC_007109.1.

3D structure databases

ProteinModelPortalQ4UK99.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING315456.RF_1185.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAY62036; AAY62036; RF_1185.
GeneID3401483.
KEGGrfe:RF_1185.
PATRIC17893224. VBIRicFel64634_1425.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1253.
HOGENOMHOG000062294.
OMADERDNIA.
OrthoDBEOG60W7V4.
ProtClustDBCLSK871055.

Enzyme and pathway databases

BioCycRFEL315456:GKEK-1219-MONOMER.

Family and domain databases

Gene3D3.30.465.10. 1 hit.
InterProIPR000644. CBS_dom.
IPR016169. CO_DH_flavot_FAD-bd_sub2.
IPR016166. FAD-bd_2.
IPR005170. Transptr-assoc_dom.
[Graphical view]
PfamPF00571. CBS. 1 hit.
PF03471. CorC_HlyC. 1 hit.
[Graphical view]
SMARTSM00116. CBS. 2 hits.
SM01091. CorC_HlyC. 1 hit.
[Graphical view]
SUPFAMSSF56176. SSF56176. 1 hit.
PROSITEPS51371. CBS. 2 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameHLYC_RICFE
AccessionPrimary (citable) accession number: Q4UK99
Entry history
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: July 5, 2005
Last modified: February 19, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Uncharacterized protein families (UPF)

List of uncharacterized protein family (UPF) entries

SIMILARITY comments

Index of protein domains and families

Rickettsia felis (Rickettsia azadi)

Rickettsia felis (strain URRWXCal2): entries and gene names