Reviewed, UniProtKB/Swiss-Prot Q4UK94 (GLRX2_RICFE)

Names and origin

Protein names

Recommended name:
    Probable monothiol glutaredoxin-2

Gene names

Name:	grxC2
Synonyms:	grlA
Ordered Locus Names:	RF_1190

Organism

Rickettsia felis (Rickettsia azadi) [Complete proteome] [HAMAP]

Taxonomic identifier

42862 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group

Protein attributes

Sequence length	104 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Sequence similarities

Belongs to the glutaredoxin family. Monothiol subfamily. Contains 1 glutaredoxin domain.

Ontologies

Keywords
Biological process	Electron transport Transport
Domain	Redox-active center
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cell redox homeostasis Inferred from electronic annotation. Source: InterPro electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW transport Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	electron carrier activity Inferred from electronic annotation. Source: InterPro protein disulfide oxidoreductase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 104	104	Probable monothiol glutaredoxin-2		PRO_0000288732
Regions
	Domain	7 – 104	98	Glutaredoxin
Sites
	Active site	32	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q4UK94-1 [UniParc]. Last modified July 5, 2005. Version 1. Checksum: 9BE58663ECB9AFE4	FASTA	104	11,918
	10 20 30 40 50 60 MTENKNFEFI ENEIKNNKVV LFMKGTKEAT MCGFSAKVVA ILNKLGVEFR DINVFVNPEF 70 80 90 100 REDLKKFSDW PTFPQLYIKG ELVGGCDIAT ELYNNGELEK MLKG

References

[1]

"The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite." Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D. PLoS Biol. 3:1-12(2005) [PubMed: 15984913] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-1525 / URRWXCal2.

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000053 Genomic DNA. Translation: AAY62041.1.
RefSeq	YP_247206.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3401488.
GenomeReviews	Gene locus RF_1190 in contig CP000053_GR.
KEGG	rfe:RF_1190.
NMPDR	fig|315456.3.peg.1190.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q4UK94.
OMA	Q4UK94. VDYKGIN.
Enzyme and pathway databases
BioCyc	RFEL315456:RF_1190-MON.
Family and domain databases
InterPro	IPR002109. Glutaredoxin. IPR004480. Glutredox-rel. IPR014434. Monothiol_GRX. IPR012335. Thioredoxin_fold. [Graphical view]
Gene3D	G3DSA:3.40.30.10. Thioredoxin_fold. 1 hit.
PANTHER	PTHR10293. Glutredox-rel. 1 hit.
Pfam	PF00462. Glutaredoxin. 1 hit. [Graphical view]
PIRSF	PIRSF005894. Monothiol_GRX. 1 hit.
TIGRFAMs	TIGR00365. Glutredox-rel. 1 hit.
PROSITE	PS51354. GLUTAREDOXIN_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLRX2_RICFE

Accession

Primary (citable) accession number: Q4UK94

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 29, 2007
Last sequence update:	July 5, 2005
Last modified:	June 16, 2009
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)