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Q4UK29 (NUOJ_RICFE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
NADH-quinone oxidoreductase subunit J

EC=1.6.99.5
Alternative name(s):
NADH dehydrogenase I subunit J
NDH-1 subunit J
Gene names
Name:nuoJ
Ordered Locus Names:RF_1255
OrganismRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) [Complete proteome] [HAMAP]
Taxonomic identifier315456 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group

Protein attributes

Sequence length205 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient By similarity.

Catalytic activity

NADH + quinone = NAD+ + quinol.

Subcellular location

Cell membrane; Multi-pass membrane protein.

Sequence similarities

Belongs to the complex I subunit 6 family.

Ontologies

Keywords
   Cellular componentCell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   LigandNAD
   Molecular functionOxidoreductase
   PTMQuinone
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionNADH dehydrogenase (ubiquinone) activity

Inferred from electronic annotation. Source: InterPro

quinone binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 205205NADH-quinone oxidoreductase subunit J
PRO_0000287840

Regions

Transmembrane1 – 2121Helical; Potential
Transmembrane26 – 4621Helical; Potential
Transmembrane54 – 7421Helical; Potential
Transmembrane89 – 10921Helical; Potential
Transmembrane142 – 16221Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q4UK29 [UniParc].

Last modified July 5, 2005. Version 1.
Checksum: FAEB95E442AB791B

FASTA20522,943
        10         20         30         40         50         60 
MFIFFYLFAT LITISSLCVV LSKNSVYSVL WLIFAFINGA GLMILLGAEF LAMMLIVIYV 

        70         80         90        100        110        120 
GAVAVLFLFV IMMLDMHFNK TITQLKENLA LSSFIALIMF ADLVTIILLG TKNINFISDV 

       130        140        150        160        170        180 
SFTITNDISN TKAIGKVLYT DFMLPFQMAG LILFVAMIAC ITLTLKKREG VKHQDITKQL 

       190        200 
SHNKSNVVLM TKPTLNKGVE NIKYE 

« Hide

References

[1]"The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-1525 / URRWXCal2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000053 Genomic DNA. Translation: AAY62106.1.
RefSeqYP_247271.1. NC_007109.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING315456.RF_1255.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAY62106; AAY62106; RF_1255.
GeneID3401366.
KEGGrfe:RF_1255.
PATRIC17893392. VBIRicFel64634_1508.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0839.
HOGENOMHOG000262592.
KOK00339.
OMAYLYPVEI.
OrthoDBEOG6Q2SPV.

Enzyme and pathway databases

BioCycRFEL315456:GKEK-1290-MONOMER.

Family and domain databases

InterProIPR001457. NADH_UbQ/plastoQ_OxRdtase_su6.
[Graphical view]
PfamPF00499. Oxidored_q3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameNUOJ_RICFE
AccessionPrimary (citable) accession number: Q4UK29
Entry history
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: July 5, 2005
Last modified: May 14, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia felis (Rickettsia azadi)

Rickettsia felis (strain URRWXCal2): entries and gene names