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Protein

NADH-quinone oxidoreductase subunit J

Gene

nuoJ

Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).By similarity

Catalytic activityi

NADH + a quinone = NAD+ + a quinol.

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NAD

Enzyme and pathway databases

BioCyciRFEL315456:GKEK-1290-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
NADH-quinone oxidoreductase subunit J (EC:1.6.5.11)
Alternative name(s):
NADH dehydrogenase I subunit J
NDH-1 subunit J
Gene namesi
Name:nuoJ
Ordered Locus Names:RF_1255
OrganismiRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)
Taxonomic identifieri315456 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
ProteomesiUP000008548 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei1 – 2121HelicalSequence AnalysisAdd
BLAST
Transmembranei26 – 4621HelicalSequence AnalysisAdd
BLAST
Transmembranei54 – 7421HelicalSequence AnalysisAdd
BLAST
Transmembranei89 – 10921HelicalSequence AnalysisAdd
BLAST
Transmembranei142 – 16221HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 205205NADH-quinone oxidoreductase subunit JPRO_0000287840Add
BLAST

Keywords - PTMi

Quinone

Interactioni

Protein-protein interaction databases

STRINGi315456.RF_1255.

Family & Domainsi

Sequence similaritiesi

Belongs to the complex I subunit 6 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0839.
HOGENOMiHOG000262592.
KOiK00339.
OMAiSPKILCT.
OrthoDBiEOG6Q2SPV.

Family and domain databases

InterProiIPR001457. NADH_UbQ/plastoQ_OxRdtase_su6.
[Graphical view]
PfamiPF00499. Oxidored_q3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4UK29-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFIFFYLFAT LITISSLCVV LSKNSVYSVL WLIFAFINGA GLMILLGAEF
60 70 80 90 100
LAMMLIVIYV GAVAVLFLFV IMMLDMHFNK TITQLKENLA LSSFIALIMF
110 120 130 140 150
ADLVTIILLG TKNINFISDV SFTITNDISN TKAIGKVLYT DFMLPFQMAG
160 170 180 190 200
LILFVAMIAC ITLTLKKREG VKHQDITKQL SHNKSNVVLM TKPTLNKGVE

NIKYE
Length:205
Mass (Da):22,943
Last modified:July 5, 2005 - v1
Checksum:iFAEB95E442AB791B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000053 Genomic DNA. Translation: AAY62106.1.
RefSeqiWP_011271555.1. NC_007109.1.
YP_247271.1. NC_007109.1.

Genome annotation databases

EnsemblBacteriaiAAY62106; AAY62106; RF_1255.
KEGGirfe:RF_1255.
PATRICi17893392. VBIRicFel64634_1508.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000053 Genomic DNA. Translation: AAY62106.1.
RefSeqiWP_011271555.1. NC_007109.1.
YP_247271.1. NC_007109.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi315456.RF_1255.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAY62106; AAY62106; RF_1255.
KEGGirfe:RF_1255.
PATRICi17893392. VBIRicFel64634_1508.

Phylogenomic databases

eggNOGiCOG0839.
HOGENOMiHOG000262592.
KOiK00339.
OMAiSPKILCT.
OrthoDBiEOG6Q2SPV.

Enzyme and pathway databases

BioCyciRFEL315456:GKEK-1290-MONOMER.

Family and domain databases

InterProiIPR001457. NADH_UbQ/plastoQ_OxRdtase_su6.
[Graphical view]
PfamiPF00499. Oxidored_q3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
    Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
    PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-1525 / URRWXCal2.

Entry informationi

Entry nameiNUOJ_RICFE
AccessioniPrimary (citable) accession number: Q4UK29
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: July 5, 2005
Last modified: June 24, 2015
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia felis (Rickettsia azadi)
    Rickettsia felis (strain URRWXCal2): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.