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Q4UK18 (ATPB_RICFE) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
ATP synthase subunit beta

EC=3.6.3.14
Alternative name(s):
ATP synthase F1 sector subunit beta
F-ATPase subunit beta
Gene names
Name:atpD
Ordered Locus Names:RF_1266
OrganismRickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) [Complete proteome] [HAMAP]
Taxonomic identifier315456 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group

Protein attributes

Sequence length474 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits By similarity. HAMAP-Rule MF_01347

Catalytic activity

ATP + H2O + H+(In) = ADP + phosphate + H+(Out). HAMAP-Rule MF_01347

Subunit structure

F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a1, b2 and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF1 is attached to CF0 by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains By similarity.

Subcellular location

Cell inner membrane; Peripheral membrane protein By similarity HAMAP-Rule MF_01347.

Sequence similarities

Belongs to the ATPase alpha/beta chains family.

Sequence caution

The sequence AAY62117.1 differs from that shown. Reason: Erroneous initiation.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 474474ATP synthase subunit beta HAMAP-Rule MF_01347
PRO_0000254363

Regions

Nucleotide binding153 – 1608ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q4UK18 [UniParc].

Last modified October 31, 2006. Version 2.
Checksum: A70DFF2D9040B16A

FASTA47451,191
        10         20         30         40         50         60 
MTKNIGKITQ IISAVVDVKF TNNGELPEIL NALECYNDKQ RIVLEVAQHI GDDTVRCIAM 

        70         80         90        100        110        120 
DSTEGLVRGV EVIDTGSPIR IPVGTETLGR IMNVVGEPID GKGDIKSSNI SSIYKSAPDF 

       130        140        150        160        170        180 
TNQSTERNIL VTGIKVVDLL APYTKGGKIG LFGGAGVGKT VLIMELINNV AKAHGGYTVF 

       190        200        210        220        230        240 
AGVGERTREG NDLYHEMIDS GVIDLEKPEN SKVALVYGQM NEPPGARARV ALSGLTIAES 

       250        260        270        280        290        300 
FRDMNEGQDV LFFVDNIFRF TQAGSEVSAL LGRIPSAVGY QPTLATDMGE LQERITSTKN 

       310        320        330        340        350        360 
GSITSVQAIY VPADDLTDPA PATSFAHLDA TTVLSRQIAE LGIYPAVDPL DSNSQVLDPM 

       370        380        390        400        410        420 
IVGEEHYSVA RQVQQILQTY KSLQDIIAIL GMDELSEEDK LTVSRARKIQ RFLSQPFHVA 

       430        440        450        460        470 
EVFTGAEGKF VNLADTIAGF KGLVEGKYDD LPEAAFYMVG TMDEAIEKAK ILKG 

« Hide

References

[1]"The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite."
Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.
PLoS Biol. 3:1-12(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-1525 / URRWXCal2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000053 Genomic DNA. Translation: AAY62117.1. Different initiation.
RefSeqYP_247282.1. NC_007109.1.

3D structure databases

ProteinModelPortalQ4UK18.
SMRQ4UK18. Positions 6-463.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING315456.RF_1266.

Proteomic databases

PRIDEQ4UK18.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAY62117; AAY62117; RF_1266.
GeneID3401377.
KEGGrfe:RF_1266.
PATRIC17893426. VBIRicFel64634_1525.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0055.
HOGENOMHOG000009605.
KOK02112.
OMAKYLSQPF.
OrthoDBEOG6HQSP3.

Enzyme and pathway databases

BioCycRFEL315456:GKEK-1301-MONOMER.

Family and domain databases

Gene3D1.10.1140.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPMF_01347. ATP_synth_beta_bact.
InterProIPR003593. AAA+_ATPase.
IPR020003. ATPase_a/bsu_AS.
IPR005722. ATPase_F1-cplx_bsu.
IPR000793. ATPase_F1/V1/A1-cplx_a/bsu_C.
IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd.
IPR004100. ATPase_F1_a/bsu_N.
IPR024034. ATPase_F1_bsu/V1_C.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamPF00006. ATP-synt_ab. 1 hit.
PF00306. ATP-synt_ab_C. 1 hit.
PF02874. ATP-synt_ab_N. 1 hit.
[Graphical view]
SMARTSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMSSF47917. SSF47917. 1 hit.
SSF50615. SSF50615. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR01039. atpD. 1 hit.
PROSITEPS00152. ATPASE_ALPHA_BETA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameATPB_RICFE
AccessionPrimary (citable) accession number: Q4UK18
Entry history
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: October 31, 2006
Last modified: June 11, 2014
This is version 78 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia felis (Rickettsia azadi)

Rickettsia felis (strain URRWXCal2): entries and gene names