ID   PLD_RICFE               Reviewed;         200 AA.
AC   Q4UJZ1;
DT   06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2005, sequence version 1.
DT   16-JUN-2009, entry version 26.
DE   RecName: Full=Phospholipase D;
DE            Short=PLD;
DE            EC=3.1.4.4;
DE   AltName: Full=Choline phosphatase;
DE   Flags: Precursor;
GN   Name=pld; OrderedLocusNames=RF_1297;
OS   Rickettsia felis (Rickettsia azadi).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
OX   NCBI_TaxID=42862;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC VR-1525 / URRWXCal2;
RX   PubMed=15984913; DOI=10.1371/journal.pbio.0030248;
RA   Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E.,
RA   Parinello H., Claverie J.-M., Raoult D.;
RT   "The genome sequence of Rickettsia felis identifies the first putative
RT   conjugative plasmid in an obligate intracellular parasite.";
RL   PLoS Biol. 3:1-12(2005).
CC   -!- FUNCTION: Could be a virulence factor (By similarity).
CC   -!- CATALYTIC ACTIVITY: A phosphatidylcholine + H(2)O = choline + a
CC       phosphatidate.
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Secreted (Potential).
CC   -!- SIMILARITY: Belongs to the phospholipase D family.
CC   -!- SIMILARITY: Contains 1 PLD phosphodiesterase domain.
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DR   EMBL; CP000053; AAY62148.1; -; Genomic_DNA.
DR   RefSeq; YP_247313.1; -.
DR   GeneID; 3400852; -.
DR   GenomeReviews; CP000053_GR; RF_1297.
DR   KEGG; rfe:RF_1297; -.
DR   NMPDR; fig|315456.3.peg.1297; -.
DR   HOGENOM; Q4UJZ1; -.
DR   OMA; Q4UJZ1; PIHHDKV.
DR   BioCyc; RFEL315456:RF_1297-MON; -.
DR   BRENDA; 3.1.4.4; 297363.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0070290; F:NAPE-specific phospholipase D activity; IEA:EC.
DR   GO; GO:0004630; F:phospholipase D activity; IEA:EC.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.
DR   InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR   PROSITE; PS50035; PLD; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Hydrolase; Lipid degradation; Secreted; Signal;
KW   Virulence.
FT   SIGNAL        1     25       Potential.
FT   CHAIN        26    200       Phospholipase D.
FT                                /FTId=PRO_0000274783.
FT   DOMAIN      142    169       PLD phosphodiesterase.
FT   ACT_SITE    147    147       Potential.
FT   ACT_SITE    149    149       Potential.
FT   ACT_SITE    154    154       Potential.
SQ   SEQUENCE   200 AA;  22501 MW;  23E3ABF9A152C41B CRC64;
     MKRKNNKFIE ISIAFILGVA LGIYGQNPDY FTNLINQKSL ASSAPKIKHY NISELLRSKV
     STCFTPPAGC TKFIANQIDR AEESIYMQAY GMSDALITTA LINAQMRGVK VRILLDRSNL
     KQKFSKLHEL QRAKIDVGID KVPGIAHNKV IIIDRKKVIT GSFNFTAAAD KRNAENVIII
     EDRELAESYL QNWLNRKASN
//