Reviewed,
UniProtKB/Swiss-Prot Q4U3Y2 (HXK1_ASPFU)
Last modified
November 3, 2009.
Version 29.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Hexokinase-1 EC=2.7.1.1 Alternative name(s): Hexokinase I | ||||
| Gene names |
| ||||
| Organism | Aspergillus fumigatus (Sartorya fumigata) [Complete proteome] | ||||
| Taxonomic identifier | 5085 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › mitosporic Trichocomaceae › Aspergillus |
Protein attributes
| Sequence length | 549 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at transcript level. |
General annotation (Comments)
| Catalytic activity | ATP + D-hexose = ADP + D-hexose 6-phosphate. |
| Pathway | |
| Sequence similarities | Belongs to the hexokinase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Glycolysis |
| Ligand | ATP-binding Nucleotide-binding |
| Molecular function | Kinase Transferase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | glycolysis Inferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | ATP binding Inferred from electronic annotation. Source: UniProtKB-KW hexokinase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Hexokinase I from Aspergillus fumigatus YJ407." Ouyang H., Zhou H., Jin C. Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: YJ-407. |
| [2] | "Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus." Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J., Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W., Bowyer P., Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.L. Denning D.W.Nature 438:1151-1156(2005) [PubMed: 16372009] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Af293 / CBS 101355 / FGSC A1100. |
Cross-references
Sequence databases | |
|---|---|
| DQ013853 mRNA. Translation: AAY42969.1. AAHF01000009 Genomic DNA. Translation: EAL87066.1. | |
| RefSeq | XP_749104.1. |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q4U3Y2. |
Genome annotation databases | |
| GeneID | 3506468. |
| GenomeReviews | Gene locus hxkA in contig CM000175_GR. |
| KEGG | afm:AFUA_7G04040. |
Phylogenomic databases | |
| OMA | CMLPSYN. |
Enzyme and pathway databases | |
| BRENDA | 2.7.1.1. 18841. |
Family and domain databases | |
| InterPro | IPR001312. Hexokinase. IPR019807. Hexokinase_CS. [Graphical view] |
| PANTHER | PTHR19443. Hexokinase. 1 hit. |
| Pfam | PF00349. Hexokinase_1. 1 hit. PF03727. Hexokinase_2. 1 hit. [Graphical view] |
| PRINTS | PR00475. HEXOKINASE. |
| ProDom | PD001109. Hexokinase. 1 hit. [Graphical view] [Entries sharing at least one domain] |
| PROSITE | PS00378. HEXOKINASES. False negative. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | HXK1_ASPFU | ||||||||
| Accession | Primary (citable) accession number: Q4U3Y2 Secondary accession number(s): Q4WG75 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | FPAP (Fungal Proteome Annotation Project) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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