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Q4U108

- Q4U108_MOUSE

UniProt

Q4U108 - Q4U108_MOUSE

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Protein
Submitted name: NF-kB2 splice variant 1
Gene
Nfkb2
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. sequence-specific DNA binding transcription factor activity Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. NIK/NF-kappaB signaling Source: MGI
  2. extracellular matrix organization Source: MGI
  3. follicular dendritic cell differentiation Source: MGI
  4. germinal center formation Source: MGI
  5. lymph node development Source: MGI
  6. spleen development Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
NF-kB2 splice variant 1Imported
Gene namesi
Name:Nfkb2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1099800. Nfkb2.

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotation

Expressioni

Gene expression databases

GenevestigatoriQ4U108.

Structurei

3D structure databases

ProteinModelPortaliQ4U108.
SMRiQ4U108. Positions 37-327.

Family & Domainsi

Sequence similaritiesi

Contains 6 ANK repeats.UniRule annotation

Keywords - Domaini

ANK repeatUniRule annotation, RepeatUniRule annotation

Phylogenomic databases

HOVERGENiHBG052613.
InParanoidiQ4U108.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
2.60.40.10. 1 hit.
2.60.40.340. 1 hit.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002909. IPT.
IPR000451. NF_Rel_Dor.
IPR008967. p53-like_TF_DNA-bd.
IPR011539. RHD.
[Graphical view]
PfamiPF00023. Ank. 1 hit.
PF12796. Ank_2. 2 hits.
PF00554. RHD. 1 hit.
[Graphical view]
PRINTSiPR00057. NFKBTNSCPFCT.
SMARTiSM00248. ANK. 6 hits.
SM00429. IPT. 1 hit.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
SSF49417. SSF49417. 1 hit.
SSF81296. SSF81296. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 5 hits.
PS01204. REL_1. 1 hit.
PS50254. REL_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4U108-1 [UniParc]FASTAAdd to Basket

« Hide

MDNCYDPGLD GIPEYDDFEF SPSIVEPKDP APETADGPYL VIVEQPKQRG    50
FRFRYGCEGP SHGGLPGASS EKGRKTYPTV KICNYEGPAK IGVDLVTHSD 100
PPRAHAHSLV GKQCSELGVC AVSVGPKDMT AQFNNLGVLH VTKKNMMEIM 150
IQKLQRQRLR SKPQGLTEAE RRELEQEAKE LKKVMDLSIV RLRFSAFLRA 200
SDGSFSLPLK PVISQPIHDS KSPGASNLKI SRMDKTAGSV RGGDEVYLLC 250
DKVQKDDIEV RFYEDDENGW QAFGDFSPTD VHKQYAIVFR TPPYHKMKIE 300
RPVTVFLQLK RKRGGDVSDS KQFTYYPLVE DKEEVQRKRR KALPTFSQPF 350
GGGSHMGGGS GGSAGGYGGA GGGGSLGFFS SSLAYNPYQS GAAPMGYYPG 400
GGGGAQMAGS RRDTDAGEGA EEPRTPPEAP QGEPQALDTL QRAREYNARL 450
FGLAQRSARA LLDYGVTADA RALLAGQRHL LMAQDENGDT PLHLAIIHGQ 500
TGVIEQIAHV IYHAQYLGVI NLTNHLHQTP LHLAVITGQT RVVSFLLQVG 550
ADPTLLDRHG DSALHLALRA GAAAPELLQA LLRSGAHAVP QILHMPDFEG 600
LYPVHLAVHA RSPECLDLLV DCGAEVEAPE RQGGRTALHL ATEMEELGLV 650
THLVTKLHAN VNARTFAGNT PLHLAAGLGS PTLTRLLLKA GTDIHAENEE 700
PLCPLPSPST SGSDSDSEGP ERDTQRNFRG HTPLDLTCST KGQGCPWGMQ 750
PCRTWSNCWM VPKPRAAGQS WQSDWG 776
Length:776
Mass (Da):84,205
Last modified:July 19, 2005 - v1
Checksum:i447A403AAE006274
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DQ020182 mRNA. Translation: AAY44750.1.
UniGeneiMm.102365.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DQ020182 mRNA. Translation: AAY44750.1 .
UniGenei Mm.102365.

3D structure databases

ProteinModelPortali Q4U108.
SMRi Q4U108. Positions 37-327.
ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:1099800. Nfkb2.

Phylogenomic databases

HOVERGENi HBG052613.
InParanoidi Q4U108.

Miscellaneous databases

ChiTaRSi NFKB2. mouse.
SOURCEi Search...

Gene expression databases

Genevestigatori Q4U108.

Family and domain databases

Gene3Di 1.25.40.20. 1 hit.
2.60.40.10. 1 hit.
2.60.40.340. 1 hit.
InterProi IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002909. IPT.
IPR000451. NF_Rel_Dor.
IPR008967. p53-like_TF_DNA-bd.
IPR011539. RHD.
[Graphical view ]
Pfami PF00023. Ank. 1 hit.
PF12796. Ank_2. 2 hits.
PF00554. RHD. 1 hit.
[Graphical view ]
PRINTSi PR00057. NFKBTNSCPFCT.
SMARTi SM00248. ANK. 6 hits.
SM00429. IPT. 1 hit.
[Graphical view ]
SUPFAMi SSF48403. SSF48403. 1 hit.
SSF49417. SSF49417. 1 hit.
SSF81296. SSF81296. 1 hit.
PROSITEi PS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 5 hits.
PS01204. REL_1. 1 hit.
PS50254. REL_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "CD14-dependent modulation of NF-kappaB alternative splicing in the lung after burn injury."
    Phan H.H., Cho K., Sainz-Lyon K.S., Shin S., Greenhalgh D.G.
    Gene 371:121-129(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: B6.129S-Cd14Imported.

Entry informationi

Entry nameiQ4U108_MOUSE
AccessioniPrimary (citable) accession number: Q4U108
Entry historyi
Integrated into UniProtKB/TrEMBL: July 19, 2005
Last sequence update: July 19, 2005
Last modified: March 19, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi