Skip Header

Contribute Send feedback
Read comments (0) or add your own

Reviewed, UniProtKB/Swiss-Prot Q4RQD3 (DUPD1_TETNG)

Last modified January 19, 2010. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Dual specificity phosphatase DUPD1
    EC=3.1.3.48
    EC=3.1.3.16
Gene names
Name: dupd1
ORF Names: GSTENG00030658001
OrganismTetraodon nigroviridis (Green puffer)
Taxonomic identifier99883 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiEuteleosteiNeoteleosteiAcanthomorphaAcanthopterygiiPercomorphaTetraodontiformesTetradontoideaTetraodontidaeTetraodon

Protein attributes

Sequence length211 AA.
Sequence statusComplete.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

A phosphoprotein + H2O = a protein + phosphate.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

Contains 1 tyrosine-protein phosphatase domain.

Sequence caution

The sequence CAG09399.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 211211Dual specificity phosphatase DUPD1
PRO_0000295889

Regions

Domain46 – 194149Tyrosine-protein phosphatase

Sites

Active site1401Phosphocysteine intermediate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q4RQD3-1 [UniParc].

Last modified July 24, 2007. Version 2.
Checksum: E752CEF4B11B86FB

FASTA21123,780
        10         20         30         40         50         60 
MSSGVKSKSR NPYTAVRVDP DSDYVTPGTL DLEQLFWTGP EVQYTHVNLV WPGIYIGDEK 

        70         80         90        100        110        120 
TALELPGLRD LGITHVLNAA EGKWNNVLTG AGYYSDANIC YYGVEADDKP TFNISQFFQP 

       130        140        150        160        170        180 
AAQFIHEALS QPHNNVLVHC VMGRSRSATL VLAYLMMRHS LSVVDAVEQV RQRRCILPNH 

       190        200        210 
GFLKQLRALD ITLQEERLRQ KREAPGQEKH T 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CAAE01015006 Genomic DNA. Translation: CAG09399.1. Sequence problems.

3D structure databases

HSSPHSSP built from PDB template 1VHR based on UniProtKB P51452.
SMRQ4RQD3. Positions 47-197.
ModBaseSearch...

Genome annotation databases

EnsemblENSTNIT00000017786; ENSTNIP00000017566; ENSTNIG00000014542; Tetraodon nigroviridis. [Genome view]

Phylogenomic databases

eggNOGveNOG15113.
HOGENOMHBG279857.
HOVERGENQ4RQD3.
InParanoidQ4RQD3.

Enzyme and pathway databases

BRENDA3.1.3.16. 295302.
3.1.3.48. 295302.

Family and domain databases

InterProIPR000387. Dual-sp/Tyr_phosphatase.
IPR020417. Dual-sp_phosphatase.
IPR000340. Dual-sp_phosphatase_cat-dom.
IPR020405. Dual-sp_phosphatase_famA.
IPR020422. Dual-sp_phosphatase_subgr_cat.
IPR016130. Tyr_Pase_AS.
[Graphical view]
PfamPF00782. DSPc. 1 hit.
[Graphical view]
PRINTSPR01908. ADSPHPHTASE.
PR01909. ADSPHPHTASEA.
SMARTSM00195. DSPc. 1 hit.
[Graphical view]
PROSITEPS00383. TYR_PHOSPHATASE_1. 1 hit.
PS50056. TYR_PHOSPHATASE_2. 1 hit.
PS50054. TYR_PHOSPHATASE_DUAL. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDUPD1_TETNG
AccessionPrimary (citable) accession number: Q4RQD3
Entry history
Integrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: July 24, 2007
Last modified: January 19, 2010
This is version 25 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents