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Q4RQD3 (DUPD1_TETNG) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Protein attributes

Sequence length211 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

Contains 1 tyrosine-protein phosphatase domain.

Sequence caution

The sequence CAG09399.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionHydrolase
Protein phosphatase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionprotein tyrosine phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-EC

protein tyrosine/serine/threonine phosphatase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 211211Dual specificity phosphatase DUPD1
PRO_0000295889

Regions

Domain46 – 194149Tyrosine-protein phosphatase
Region139 – 1468Substrate binding By similarity

Sites

Active site1401Phosphocysteine intermediate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q4RQD3 [UniParc].

Last modified July 24, 2007. Version 2.
Checksum: E752CEF4B11B86FB

FASTA21123,780
        10         20         30         40         50         60 
MSSGVKSKSR NPYTAVRVDP DSDYVTPGTL DLEQLFWTGP EVQYTHVNLV WPGIYIGDEK 

        70         80         90        100        110        120 
TALELPGLRD LGITHVLNAA EGKWNNVLTG AGYYSDANIC YYGVEADDKP TFNISQFFQP 

       130        140        150        160        170        180 
AAQFIHEALS QPHNNVLVHC VMGRSRSATL VLAYLMMRHS LSVVDAVEQV RQRRCILPNH 

       190        200        210 
GFLKQLRALD ITLQEERLRQ KREAPGQEKH T 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CAAE01015006 Genomic DNA. Translation: CAG09399.1. Sequence problems.

3D structure databases

ProteinModelPortalQ4RQD3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING99883.ENSTNIP00000017566.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

eggNOGCOG2453.
HOGENOMHOG000232100.
HOVERGENHBG001524.
InParanoidQ4RQD3.

Family and domain databases

Gene3D3.90.190.10. 1 hit.
InterProIPR020417. Atypical_DUSP.
IPR020405. Atypical_DUSP_famA.
IPR000340. Dual-sp_phosphatase_cat-dom.
IPR020422. Dual-sp_phosphatase_subgr_cat.
IPR024950. DUSP.
IPR029021. Prot-tyrosine_phosphatase-like.
IPR000387. Tyr/Dual-sp_Pase.
IPR016130. Tyr_Pase_AS.
[Graphical view]
PANTHERPTHR10159. PTHR10159. 1 hit.
PfamPF00782. DSPc. 1 hit.
[Graphical view]
PRINTSPR01908. ADSPHPHTASE.
PR01909. ADSPHPHTASEA.
SMARTSM00195. DSPc. 1 hit.
[Graphical view]
SUPFAMSSF52799. SSF52799. 1 hit.
PROSITEPS00383. TYR_PHOSPHATASE_1. 1 hit.
PS50056. TYR_PHOSPHATASE_2. 1 hit.
PS50054. TYR_PHOSPHATASE_DUAL. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDUPD1_TETNG
AccessionPrimary (citable) accession number: Q4RQD3
Entry history
Integrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: July 24, 2007
Last modified: June 11, 2014
This is version 46 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families