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Protein

Ropporin-1-like protein

Gene

ROPN1L

Organism
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Important for male fertility. With ROPN1, involved in fibrous sheath integrity and sperm motility, plays a role in PKA-dependent signaling processes required for spermatozoa capacitation.By similarity

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Ropporin-1-like protein
Gene namesi
Name:ROPN1L
ORF Names:QtsA-16243
OrganismiMacaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Taxonomic identifieri9541 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca

Subcellular locationi

Keywords - Cellular componenti

Cell projection

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003073991 – 230Ropporin-1-like proteinAdd BLAST230

Post-translational modificationi

Sumoylated, sumoylation decreases upon spermatozoa capacitation conditions.By similarity

Keywords - PTMi

Ubl conjugation

Interactioni

Subunit structurei

May interact with AKAP3 (By similarity). Interacts with FSCB; the interaction increases upon spermatozoa capacitation conditions (By similarity).By similarity

Structurei

3D structure databases

ProteinModelPortaliQ4R760.
SMRiQ4R760.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini17 – 54RIIaAdd BLAST38

Sequence similaritiesi

Belongs to the ropporin family.Curated

Phylogenomic databases

HOVERGENiHBG060390.

Family and domain databases

Gene3Di1.20.890.10. 1 hit.
InterProiView protein in InterPro
IPR036536. cAMP_dep_PK_reg_su_sf.
SUPFAMiSSF47391. SSF47391. 1 hit.

Sequencei

Sequence statusi: Complete.

Q4R760-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPLPDTMFCA QQIHIPPELP DILKQFTKAA IRTQPADVLQ WSAGYFSALS
60 70 80 90 100
RGDPLPVKDR MEMPTATQKT DTGLTPGLLK VLHKQCHHKQ YVELTDLEQK
110 120 130 140 150
WKNLCLPKEK FKALLQLDPC ENRIKWINFL ALGCSMLGGS LNTALKHLCE
160 170 180 190 200
ILTDDPEGGP ARIPFKTFSY VYRYLANLDS DVSSSETESY LASLKENIDT
210 220 230
RRNGMIGLSD FFFPKRNLLE NRENSEDVGH
Length:230
Mass (Da):26,084
Last modified:July 19, 2005 - v1
Checksum:iDBFEBEF2F4F4B665
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB168965 mRNA. Translation: BAE01063.1.
RefSeqiNP_001271606.1. NM_001284677.1.
UniGeneiMfa.7004.

Genome annotation databases

GeneIDi101865380.
KEGGimcf:101865380.

Similar proteinsi

Entry informationi

Entry nameiROP1L_MACFA
AccessioniPrimary (citable) accession number: Q4R760
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: July 19, 2005
Last modified: November 22, 2017
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families