Q4R1I9 (ANGLT_ROSHC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Anthocyanidin 5,3-O-glucosyltransferase
EC=2.4.1.-

Alternative name(s):
UDP-glucose: anthocyanidin 5,3-O-glucosyltransferase

Gene names

Name:

RhGT1

Organism

Rosa hybrid cultivar

Taxonomic identifier

128735 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › fabids › Rosales › Rosaceae › Rosoideae › Rosoideae unplaced › Rosa

Protein attributes

Sequence length	473 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Sequentially catalyzes two glycosylation steps at the 5-OH and 3-OH positions of anthocyanidin. Unglycosylated anthocyanidin or anthocyanidin 5-O-glucoside, but not anthocyanidin 3-O-glucoside, can be used as glucosyl acceptor. Ref.1
Pathway	Pigment biosynthesis; anthocyanin biosynthesis.
Miscellaneous	In roses, anthocyanidin 3,5-O-diglucoside is the first stable anthocyanin, and therefore responsible for flower coloration, whereas this is usually anthocyanidin 3-O-glucoside in other plants.
Sequence similarities	Belongs to the UDP-glycosyltransferase family.

Ontologies

Keywords
Molecular function	Glycosyltransferase Transferase
Gene Ontology (GO)
Biological_process	anthocyanin-containing compound biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	transferase activity, transferring hexosyl groups Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 473	473	Anthocyanidin 5,3-O-glucosyltransferase		PRO_0000074172

Sequences

	Sequence		Length	Mass (Da)
	Q4R1I9 [UniParc]. Last modified July 19, 2005. Version 1. Checksum: F07504B331EBE2F8	FASTA	473	51,877
	10 20 30 40 50 60 MGGDAIVLYP YPGLGHLISM VELGKLLLTH HPSFSITILA STAPTTIAAT AKLVASSNDQ 70 80 90 100 110 120 LTNYIKAVSA DNPAINFHHL PTISSLPEHI EKLNLPFEYA RLQIPNILQV LQTLKSSLKA 130 140 150 160 170 180 LILDMFCDAL FDVTKDLNIP TFYFYTSAGR SLAVLLNIPT FHRTTNSLSD FGDVPISISG 190 200 210 220 230 240 MPPIPVSAMP KLLFDRSTNF YKSFLSTSTH MAKSNGIILN TFDLLEERAL KALRAGLCLP 250 260 270 280 290 300 NQPTPPIFTV GPLISGKSGD NDEHESLKWL NNQPKDSVVF LCFGSMGVFS IKQLEAMALG 310 320 330 340 350 360 LEKSGQRFLW VVRNPPIEEL PVEEPSLEEI LPKGFVERTK DRGLVVRKWA PQVEVLSHDS 370 380 390 400 410 420 VGGFVTHCGW NSVLEAVCNG VPMVAWPLYA EQKLGRVFLV EEMKVAVGVK ESETGFVSAD 430 440 450 460 470 ELEKRVRELM DSESGDEIRG RVSEFSNGGV KAKEEGGSSV ASLAKLAQLW KQK

References

[1]	"Plant biochemistry: anthocyanin biosynthesis in roses." Ogata J., Kanno Y., Itoh Y., Tsugawa H., Suzuki M. Nature 435:757-758(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION. Strain: cv. Crimson Glory.

Web resources

Protein Spotlight

The color of the rose - Issue 63 of October 2005

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB201048 mRNA. Translation: BAD99560.1.
3D structure databases
ProteinModelPortal	Q4R1I9.
ModBase	Search...
Protein family/group databases
CAZy	GT1. Glycosyltransferase Family 1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Enzyme and pathway databases
UniPathway	UPA00009.
Family and domain databases
InterPro	IPR002213. UDP_glucos_trans. [Graphical view]
PANTHER	PTHR11926. PTHR11926. 1 hit.
Pfam	PF00201. UDPGT. 1 hit. [Graphical view]
PROSITE	PS00375. UDPGT. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ANGLT_ROSHC

Accession

Primary (citable) accession number: Q4R1I9

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 16, 2005
Last sequence update:	July 19, 2005
Last modified:	October 31, 2012
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program