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Protein
Submitted name:

Heat sensitive channel TRPV3

Gene

Trpv3

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • positive regulation of calcium ion import Source: RGD
  • response to heat Source: RGD

Names & Taxonomyi

Protein namesi
Submitted name:
Heat sensitive channel TRPV3Imported
Gene namesi
Name:Trpv3Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi1564531. Trpv3.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei439 – 461HelicalSequence analysisAdd BLAST23
Transmembranei481 – 508HelicalSequence analysisAdd BLAST28
Transmembranei520 – 541HelicalSequence analysisAdd BLAST22
Transmembranei547 – 566HelicalSequence analysisAdd BLAST20
Transmembranei587 – 609HelicalSequence analysisAdd BLAST23
Transmembranei652 – 676HelicalSequence analysisAdd BLAST25

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ4QYD9.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000026596.

Structurei

3D structure databases

ProteinModelPortaliQ4QYD9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini167 – 361ANK_REP_REGIONInterPro annotationAdd BLAST195
Repeati214 – 246ANKPROSITE-ProRule annotationAdd BLAST33
Repeati340 – 361ANKPROSITE-ProRule annotationAdd BLAST22

Sequence similaritiesi

Belongs to the transient receptor (TC 1.A.4) family. [View classification]SAAS annotation

Keywords - Domaini

ANK repeatPROSITE-ProRule annotationSAAS annotation, RepeatSAAS annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3676. Eukaryota.
ENOG4110DG4. LUCA.
HOGENOMiHOG000234630.
HOVERGENiHBG054085.
PhylomeDBiQ4QYD9.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
InterProiView protein in InterPro
IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR005821. Ion_trans_dom.
IPR024862. TRPV.
IPR008347. TRPV1-4_channel.
IPR024866. TRPV3_channel.
PANTHERiPTHR10582. PTHR10582. 1 hit.
PTHR10582:SF40. PTHR10582:SF40. 1 hit.
PfamiView protein in Pfam
PF12796. Ank_2. 1 hit.
PF00520. Ion_trans. 1 hit.
PRINTSiPR01768. TRPVRECEPTOR.
SMARTiView protein in SMART
SM00248. ANK. 4 hits.
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiView protein in PROSITE
PS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 2 hits.

Sequencei

Sequence statusi: Complete.

Q4QYD9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKAHPKEMVP LMGKRTTAPG GNPAVLTEKR PADLTPTKKS AHFFLEIEGF
60 70 80 90 100
EPNPTVTKTS PPIFSKPMDS NIRQCLSGNC DDMDSPQSPQ DDVTETPSNP
110 120 130 140 150
NSPSANLAKE EQRQKKKRLK KCIFAAVSEG CVRELRELLQ DLQELCRRRR
160 170 180 190 200
GLDASDFLMH KLTASDTGKT CLMKALLNIN PNTKEIVRIL LAFAEENDIL
210 220 230 240 250
DRFINAEYTE EAYEGQTALN IAIERRQGDI TAVLIAAGAD VNAHAKGVFF
260 270 280 290 300
NPKYQHEGFY FGETPLALAA CTNQPEIVQL LMENEQTDIT SQDSRGNNIL
310 320 330 340 350
HALVTVAEDF KTQNDFVKRM YDMILLRSGN WELETMRNND GLTPLQLAAK
360 370 380 390 400
MGKAEILKYI LGREIKEKPL RSLSRKFTDW AYGPVSSSLY DLTNVDTTTD
410 420 430 440 450
NSVLEIIVYN TNIDNRHEVL TLEPLHTLLH MKWKKFAKYM FFLSFCFYFS
460 470 480 490 500
YNITLTLVSY YRPREGEALP HPLALTHKMS WLQLLGRMFV LIWAMCISVK
510 520 530 540 550
EGIAIFLLRP SDLQSILSDA WFHFVIFGQA VLVILSVFLY LFAYKEYLAC
560 570 580 590 600
LVLAMALGWA NMLYYTRGFQ SMGMYSVMIQ KVILHDVLKF LFVYILFLLG
610 620 630 640 650
FGVALASLIE KCSKDKKDCS SYGSFSDAVL ELFKLTIGLG GLNIQQNSTY
660 670 680 690 700
PILFLFLLIT YVILTFVLLL NMLIALMGET AENVSKESER IWRLQRARTT
710 720 730 740 750
LEFEKMLPEW LRSRFRMGEL CKVADEDFRL CLRINEVKWT EWKTHVSFLN
760 770 780 790
EDPGPIRRTA DSNKIQDSSR SNSKTTLYAF DELDEFPETS V
Length:791
Mass (Da):90,273
Last modified:July 19, 2005 - v1
Checksum:i4B79B03B3F9BF7AB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY325813 mRNA. Translation: AAQ90060.1.
UniGeneiRn.163151.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY325813 mRNA. Translation: AAQ90060.1.
UniGeneiRn.163151.

3D structure databases

ProteinModelPortaliQ4QYD9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000026596.

Proteomic databases

PaxDbiQ4QYD9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

RGDi1564531. Trpv3.

Phylogenomic databases

eggNOGiKOG3676. Eukaryota.
ENOG4110DG4. LUCA.
HOGENOMiHOG000234630.
HOVERGENiHBG054085.
PhylomeDBiQ4QYD9.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
InterProiView protein in InterPro
IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR005821. Ion_trans_dom.
IPR024862. TRPV.
IPR008347. TRPV1-4_channel.
IPR024866. TRPV3_channel.
PANTHERiPTHR10582. PTHR10582. 1 hit.
PTHR10582:SF40. PTHR10582:SF40. 1 hit.
PfamiView protein in Pfam
PF12796. Ank_2. 1 hit.
PF00520. Ion_trans. 1 hit.
PRINTSiPR01768. TRPVRECEPTOR.
SMARTiView protein in SMART
SM00248. ANK. 4 hits.
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiView protein in PROSITE
PS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiQ4QYD9_RAT
AccessioniPrimary (citable) accession number: Q4QYD9
Entry historyiIntegrated into UniProtKB/TrEMBL: July 19, 2005
Last sequence update: July 19, 2005
Last modified: February 15, 2017
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.