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Protein

Peroxisomal membrane protein PEX16

Gene

pex16

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Involved in peroxisome biogenesis.By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Peroxisome biogenesis

Names & Taxonomyi

Protein namesi
Recommended name:
Peroxisomal membrane protein PEX16
Alternative name(s):
Peroxin-16
Peroxisomal biogenesis factor 16
Gene namesi
Name:pex16
ORF Names:zgc:112248
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Unplaced

Organism-specific databases

ZFINiZDB-GENE-050626-49. pex16.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 80CytoplasmicSequence analysisAdd BLAST80
Transmembranei81 – 101HelicalSequence analysisAdd BLAST21
Topological domaini102 – 109PeroxisomalSequence analysis8
Transmembranei110 – 130HelicalSequence analysisAdd BLAST21
Topological domaini131 – 335CytoplasmicSequence analysisAdd BLAST205

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane, Peroxisome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003669621 – 335Peroxisomal membrane protein PEX16Add BLAST335

Proteomic databases

PaxDbiQ4QRH7.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000111182.

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni66 – 81Required for peroxisomal locationBy similarityAdd BLAST16
Regioni220 – 335Interaction with PEX19By similarityAdd BLAST116

Sequence similaritiesi

Belongs to the peroxin-16 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG4546. Eukaryota.
ENOG4111GEA. LUCA.
HOGENOMiHOG000008062.
HOVERGENiHBG053572.
InParanoidiQ4QRH7.
KOiK13335.
PhylomeDBiQ4QRH7.

Family and domain databases

InterProiIPR013919. Pex16.
[Graphical view]
PfamiPF08610. Pex16. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4QRH7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKLTRVFER YQEYVRTSPA AASHLESTVR ALSYLIAGRF SDSHEISELV
60 70 80 90 100
YSASNLLVLL NDGILRKNLS RTLPMSISQQ KLLTWLSVLE YVEVFVEMAA
110 120 130 140 150
AKMWGDAGRW LVIVLIQIAK AVLRCLLLFW YKSGIQTSPP IIPLDRDSQL
160 170 180 190 200
CSQDNNEEED DEDSSFVGQR SGRVVRPLGS APSLQSRLWG LPRKKKVSRN
210 220 230 240 250
QEEELHSSPT PLGLQETIAE SLYIARPLLH LASLGICGKR SWKPWILSGL
260 270 280 290 300
LEITSFSLLS DMKALNRRER AEMRRRAFLL LYYLLRSPFY DRYSETKILF
310 320 330
LLRFLADYVP GVGLVARPLM EYLPIWQKIY FYNWG
Length:335
Mass (Da):38,555
Last modified:July 19, 2005 - v1
Checksum:i6CBA7852A792E7F2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC096874 mRNA. Translation: AAH96874.1.
RefSeqiNP_001020340.1. NM_001025169.1.
UniGeneiDr.79352.

Genome annotation databases

GeneIDi573990.
KEGGidre:573990.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC096874 mRNA. Translation: AAH96874.1.
RefSeqiNP_001020340.1. NM_001025169.1.
UniGeneiDr.79352.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000111182.

Proteomic databases

PaxDbiQ4QRH7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi573990.
KEGGidre:573990.

Organism-specific databases

CTDi9409.
ZFINiZDB-GENE-050626-49. pex16.

Phylogenomic databases

eggNOGiKOG4546. Eukaryota.
ENOG4111GEA. LUCA.
HOGENOMiHOG000008062.
HOVERGENiHBG053572.
InParanoidiQ4QRH7.
KOiK13335.
PhylomeDBiQ4QRH7.

Miscellaneous databases

PROiQ4QRH7.

Family and domain databases

InterProiIPR013919. Pex16.
[Graphical view]
PfamiPF08610. Pex16. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPEX16_DANRE
AccessioniPrimary (citable) accession number: Q4QRH7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: July 19, 2005
Last modified: July 6, 2016
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.