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Protein

RNA pseudouridylate synthase domain-containing protein 4

Gene

Rpusd4

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei153 – 1531By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
RNA pseudouridylate synthase domain-containing protein 4
Gene namesi
Name:Rpusd4
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 8

Organism-specific databases

RGDi1311268. Rpusd4.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 377377RNA pseudouridylate synthase domain-containing protein 4PRO_0000300827Add
BLAST

Proteomic databases

PaxDbiQ4QQT0.
PRIDEiQ4QQT0.

Expressioni

Gene expression databases

GenevisibleiQ4QQT0. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000015670.

Structurei

3D structure databases

ProteinModelPortaliQ4QQT0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase RluA family.Curated

Phylogenomic databases

eggNOGiKOG1919. Eukaryota.
COG0564. LUCA.
GeneTreeiENSGT00530000063800.
HOGENOMiHOG000136349.
HOVERGENiHBG054698.
InParanoidiQ4QQT0.
OMAiVLAWEKD.
OrthoDBiEOG7WT41T.
PhylomeDBiQ4QQT0.
TreeFamiTF337899.

Family and domain databases

InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR006224. PsdUridine_synth_RluC/D_CS.
IPR006145. PsdUridine_synth_RsuA/RluD.
[Graphical view]
PfamiPF00849. PseudoU_synth_2. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
PROSITEiPS01129. PSI_RLU. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4QQT0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAPLLGSPG LQVLSMSSRT GKLFTPSSRS FCSRATSSRP LNAQRLAEKL
60 70 80 90 100
RAQKQEQKTK EMRVPTNPVQ RRVQELVRFT QQLQRVHPNV LAKELSRRIL
110 120 130 140 150
HQDKDLVVIN KPYGLPVHGG PGVQLCISDV LPILAKMLHG HKAEPLHLCH
160 170 180 190 200
RLDKETTGVM VLAWEKDMAH QVQELFRTRQ VEKKYWAITV RVPLPSAGVV
210 220 230 240 250
DIPIMEKEVA GQQQHHKMTL RPSYRMDNGK MVKVRASRDA HVAVTQYQVL
260 270 280 290 300
SSTPSSALVE LQPVTGIKHQ LRVHLAFGLD CPILGDHKYS DWNRLAPQKL
310 320 330 340 350
SAGTLKKLGL QQSKARYIPL HLHARQLILP ALGSRTEELL LACKLPHFFA
360 370
RSLRRLGLDM PNEDQSRSHE ARHVEAR
Length:377
Mass (Da):42,595
Last modified:July 19, 2005 - v1
Checksum:iBE327163AE77C30A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC098023 mRNA. Translation: AAH98023.1.
RefSeqiNP_001020455.1. NM_001025284.1.
UniGeneiRn.232042.

Genome annotation databases

EnsembliENSRNOT00000015670; ENSRNOP00000015670; ENSRNOG00000011567.
GeneIDi315550.
KEGGirno:315550.
UCSCiRGD:1311268. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC098023 mRNA. Translation: AAH98023.1.
RefSeqiNP_001020455.1. NM_001025284.1.
UniGeneiRn.232042.

3D structure databases

ProteinModelPortaliQ4QQT0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000015670.

Proteomic databases

PaxDbiQ4QQT0.
PRIDEiQ4QQT0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000015670; ENSRNOP00000015670; ENSRNOG00000011567.
GeneIDi315550.
KEGGirno:315550.
UCSCiRGD:1311268. rat.

Organism-specific databases

CTDi84881.
RGDi1311268. Rpusd4.

Phylogenomic databases

eggNOGiKOG1919. Eukaryota.
COG0564. LUCA.
GeneTreeiENSGT00530000063800.
HOGENOMiHOG000136349.
HOVERGENiHBG054698.
InParanoidiQ4QQT0.
OMAiVLAWEKD.
OrthoDBiEOG7WT41T.
PhylomeDBiQ4QQT0.
TreeFamiTF337899.

Miscellaneous databases

PROiQ4QQT0.

Gene expression databases

GenevisibleiQ4QQT0. RN.

Family and domain databases

InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR006224. PsdUridine_synth_RluC/D_CS.
IPR006145. PsdUridine_synth_RsuA/RluD.
[Graphical view]
PfamiPF00849. PseudoU_synth_2. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
PROSITEiPS01129. PSI_RLU. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Testis.

Entry informationi

Entry nameiRUSD4_RAT
AccessioniPrimary (citable) accession number: Q4QQT0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: July 19, 2005
Last modified: June 8, 2016
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.