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Protein
Submitted name:

Dsp protein

Gene

Dsp

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. poly(A) RNA binding Source: Ensembl
  2. structural molecule activity Source: Ensembl

GO - Biological processi

  1. adherens junction organization Source: Ensembl
  2. bundle of His cell to Purkinje myocyte communication Source: Ensembl
  3. desmosome organization Source: Ensembl
  4. intermediate filament organization Source: Ensembl
  5. keratinocyte differentiation Source: Ensembl
  6. peptide cross-linking Source: Ensembl
  7. protein localization to adherens junction Source: Ensembl
  8. regulation of heart rate by cardiac conduction Source: Ensembl
  9. single organismal cell-cell adhesion Source: Ensembl
  10. ventricular cardiac muscle cell action potential Source: Ensembl
  11. ventricular compact myocardium morphogenesis Source: Ensembl
  12. wound healing Source: RGD
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Dsp proteinImported
Gene namesi
Name:DspImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi1305794. Dsp.

Subcellular locationi

GO - Cellular componenti

  1. basolateral plasma membrane Source: Ensembl
  2. cornified envelope Source: Ensembl
  3. desmosome Source: RGD
  4. extracellular vesicular exosome Source: Ensembl
  5. fascia adherens Source: RGD
  6. intermediate filament Source: Ensembl
  7. membrane Source: MGI
  8. mitochondrion Source: Ensembl
  9. nucleus Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiQ4QQR7.
PRIDEiQ4QQR7.

PTM databases

PhosphoSiteiQ4QQR7.

Expressioni

Gene expression databases

ExpressionAtlasiQ4QQR7. baseline and differential.
GenevestigatoriQ4QQR7.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000018649.

Family & Domainsi

Phylogenomic databases

eggNOGiNOG12793.
HOGENOMiHOG000112198.
HOVERGENiHBG068419.
PhylomeDBiQ4QQR7.

Family and domain databases

Gene3Di3.90.1290.10. 4 hits.
InterProiIPR028462. Desmoplakin.
IPR001101. Plectin_repeat.
[Graphical view]
PANTHERiPTHR11915:SF234. PTHR11915:SF234. 1 hit.
PfamiPF00681. Plectin. 6 hits.
[Graphical view]
SMARTiSM00250. PLEC. 12 hits.
[Graphical view]
SUPFAMiSSF75399. SSF75399. 4 hits.

Sequencei

Sequence statusi: Fragment.

Q4QQR7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
LESGQISYDE VGERIKDFLQ GSSCIAGIYN ETTKQKLGIY EAMKIGLVRP
60 70 80 90 100
GTALELLEAQ AATGFIVDPV SNLRLPVEEA YKRGLVGIEF KEKLLSAERA
110 120 130 140 150
VTGYNDPETG NIISLFQAMN KELIEKGHGI RLLEAQIATG GIIDPKESHR
160 170 180 190 200
LPVDMAYKRG YFNEELSEIL SDPSDDTKGF FDPNTEENLT YLQLKERCIK
210 220 230 240 250
DEETGLCLLP LKEKKKQVQT SQKNTLRKRR VVIVDPETNK EMSVQEAYKK
260 270 280 290 300
GLIDYETFKE LCEQECEWEE ITITGSDGST RVVLVDRKTG SQYDIQDAID
310 320 330 340 350
KGLVDRKFFD QYRSGSLSLT QFADMISLKN GVGTSSGLSG SVNDDVFSSS
360 370 380 390 400
RHESVSKIST ISSVRNLTIR SSSLSDPLEE SSPIAAIFDT ENLEKISITE
410 420 430 440 450
GIERGIVDSI TGQRLLEAQA CTGGIIHPTT GQKLSLQDAV SQGLIDQDMA
460 470 480 490 500
TRLKPAQKAF IGFEGVKGKK KMSAAEAVKE KWLPYEAGQR FLEFQFLTGG
510 520 530 540 550
LVDPEVHGRI STEEAIRKGF IDGRAAQRLQ DISSYAKILT CPKTKLKISY
560 570 580 590 600
KDAMNRSMVE DITGLRLLEA ASVSSKGLPS PYNMSAPGSR SGSRSGSRSG
610 620 630
SRSGSRSGSR RGSFDATGNS SYSYSYSFSS SSIGY
Length:635
Mass (Da):69,750
Last modified:July 19, 2005 - v1
Checksum:iFB027E6B587CB1B4
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC098071 mRNA. Translation: AAH98071.1.
UniGeneiRn.231913.

Genome annotation databases

UCSCiRGD:1305794. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC098071 mRNA. Translation: AAH98071.1.
UniGeneiRn.231913.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000018649.

PTM databases

PhosphoSiteiQ4QQR7.

Proteomic databases

PaxDbiQ4QQR7.
PRIDEiQ4QQR7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

UCSCiRGD:1305794. rat.

Organism-specific databases

RGDi1305794. Dsp.

Phylogenomic databases

eggNOGiNOG12793.
HOGENOMiHOG000112198.
HOVERGENiHBG068419.
PhylomeDBiQ4QQR7.

Gene expression databases

ExpressionAtlasiQ4QQR7. baseline and differential.
GenevestigatoriQ4QQR7.

Family and domain databases

Gene3Di3.90.1290.10. 4 hits.
InterProiIPR028462. Desmoplakin.
IPR001101. Plectin_repeat.
[Graphical view]
PANTHERiPTHR11915:SF234. PTHR11915:SF234. 1 hit.
PfamiPF00681. Plectin. 6 hits.
[Graphical view]
SMARTiSM00250. PLEC. 12 hits.
[Graphical view]
SUPFAMiSSF75399. SSF75399. 4 hits.
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: PlacentaImported.

Entry informationi

Entry nameiQ4QQR7_RAT
AccessioniPrimary (citable) accession number: Q4QQR7
Entry historyi
Integrated into UniProtKB/TrEMBL: July 19, 2005
Last sequence update: July 19, 2005
Last modified: October 29, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.