Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

SLC8A1 protein

Gene

SLC8A1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
SLC8A1 proteinImported
Gene namesi
Name:SLC8A1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei209 – 233HelicalSequence analysisAdd BLAST25
Transmembranei286 – 306HelicalSequence analysisAdd BLAST21
Transmembranei318 – 338HelicalSequence analysisAdd BLAST21
Transmembranei354 – 372HelicalSequence analysisAdd BLAST19

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA314.

PTM / Processingi

Proteomic databases

PaxDbiQ4QQH3.
PeptideAtlasiQ4QQH3.

Expressioni

Gene expression databases

GenevisibleiQ4QQH3. HS.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 37Calx-betaInterPro annotationAdd BLAST36
Domaini212 – 373Na_Ca_exInterPro annotationAdd BLAST162

Sequence similaritiesi

Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. [View classification]SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG1306. Eukaryota.
ENOG410XPJP. LUCA.
HOVERGENiHBG006441.

Family and domain databases

InterProiView protein in InterPro
IPR003644. Calx_beta.
IPR004836. Na_Ca_Ex.
IPR004837. NaCa_Exmemb.
PfamiView protein in Pfam
PF03160. Calx-beta. 1 hit.
PF01699. Na_Ca_ex. 1 hit.
PRINTSiPR01259. NACAEXCHNGR.

Sequencei

Sequence statusi: Fragment.

Q4QQH3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
DTCGELEFQN DEIVKTISVK VIDDEEYEKN KTFFLEIGEP RLVEMSEKKA
60 70 80 90 100
LLLNELGGFT ITGKYLFGQP VFRKVHAREH PILSTVITIA DEYDDKQPLT
110 120 130 140 150
SKEEEERRIA EMGRPILGEH TKLEVIIEES YEFKSTVDKL IKKTNLALVV
160 170 180 190 200
GTNSWREQFI EAITVSAGED DDDDECGEEK LPSCFDYVMH FLTVFWKVLF
210 220 230 240 250
AFVPPTEYWN GWACFIVSIL MIGLLTAFIG DLASHFGCTI GLKDSVTAVV
260 270 280 290 300
FVALGTSVPD TFASKVAATQ DQYADASIGN VTGSNAVNVF LGIGVAWSIA
310 320 330 340 350
AIYHAANGEQ FKVSPGTLAF SVTLFTIFAF INVGVLLYRR RPEIGGELGG
360 370 380
PRTAKLLTSC LFVLLWLLYI FFSSLEAYCH IKGF
Length:384
Mass (Da):42,734
Last modified:July 19, 2005 - v1
Checksum:i759F0B6C87D899AF
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC098285 mRNA. Translation: AAH98285.1.
RefSeqiNP_001106271.1. NM_001112800.1.
UniGeneiHs.31961.
Hs.468274.
Hs.744988.

Genome annotation databases

GeneIDi6546.

Similar proteinsi

Entry informationi

Entry nameiQ4QQH3_HUMAN
AccessioniPrimary (citable) accession number: Q4QQH3
Entry historyiIntegrated into UniProtKB/TrEMBL: July 19, 2005
Last sequence update: July 19, 2005
Last modified: September 27, 2017
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.