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Q4QQG6 (Q4QQG6_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified March 6, 2013. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
Gene names
Name:SLC8A1 EMBL AAH98308.1
OrganismHomo sapiens (Human) EMBL AAH98308.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length335 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

Ontologies

Keywords
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix SAAS SAAS004837
Gene Ontology (GO)
   Cellular_componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functioncalcium:sodium antiporter activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q4QQG6 [UniParc].

Last modified July 19, 2005. Version 1.
Checksum: 9B2D6D9BD42B3BD0

FASTA33536,980
        10         20         30         40         50         60 
MSEKKALLLN ELGGFTITGQ PVFRKVHARE HPILSTVITI ADEYDDKQPL TSKEEEERRI 

        70         80         90        100        110        120 
AEMGRPILGE HTKLEVIIEE SYEFKSTVDK LIKKTNLALV VGTNSWREQF IEAITVSAGE 

       130        140        150        160        170        180 
DDDDDECGEE KLPSCFDYVM HFLTVFWKVL FAFVPPTEYW NGWACFIVSI LMIGLLTAFI 

       190        200        210        220        230        240 
GDLASHFGCT IGLKDSVTAV VFVALGTSVP DTFASKVAAT QDQYADASIG NVTGSNAVNV 

       250        260        270        280        290        300 
FLGIGVAWSI AAIYHAANGE QFKVSPGTLA FSVTLFTIFA FINVGVLLYR RRPEIGGELG 

       310        320        330 
GPRTAKLLTS CLFVLLWLLY IFFSSLEAYC HIKGF 

« Hide

References

[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. expand/collapse author list , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: PCR rescued clones EMBL AAH98308.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC098308 mRNA. Translation: AAH98308.1.
IPIIPI00893158.
UniGeneHs.31961.
Hs.468274.
Hs.741346.

3D structure databases

ProteinModelPortalQ4QQG6.
SMRQ4QQG6. Positions 39-89.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ4QQG6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

HOVERGENHBG006441.

Gene expression databases

ArrayExpressQ4QQG6.
BgeeQ4QQG6.

Family and domain databases

InterProIPR004836. Na_Ca_Ex.
IPR004837. NaCa_Exmemb.
[Graphical view]
PfamPF01699. Na_Ca_ex. 1 hit.
[Graphical view]
PRINTSPR01259. NACAEXCHNGR.
ProtoNetSearch...

Other

ChiTaRSSLC8A1. human.

Entry information

Entry nameQ4QQG6_HUMAN
AccessionPrimary (citable) accession number: Q4QQG6
Entry history
Integrated into UniProtKB/TrEMBL: July 19, 2005
Last sequence update: July 19, 2005
Last modified: March 6, 2013
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.