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Protein

Bis(5'-nucleosyl)-tetraphosphatase, symmetrical

Gene

apaH

Organism
Haemophilus influenzae (strain 86-028NP)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.UniRule annotation

Catalytic activityi

P1,P4-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Bis(5'-nucleosyl)-tetraphosphatase, symmetricalUniRule annotation (EC:3.6.1.41UniRule annotation)
Alternative name(s):
Ap4A hydrolaseUniRule annotation
Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolaseUniRule annotation
Diadenosine tetraphosphataseUniRule annotation
Gene namesi
Name:apaHUniRule annotation
Ordered Locus Names:NTHI0679
OrganismiHaemophilus influenzae (strain 86-028NP)
Taxonomic identifieri281310 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
Proteomesi
  • UP000002525 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000120611 – 275Bis(5'-nucleosyl)-tetraphosphatase, symmetricalAdd BLAST275

Structurei

3D structure databases

ProteinModelPortaliQ4QMZ7
SMRiQ4QMZ7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Ap4A hydrolase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000251871
KOiK01525
OMAiMPWFDVP
OrthoDBiPOG091H0691

Family and domain databases

CDDicd07422 MPP_ApaH, 1 hit
Gene3Di3.60.21.10, 1 hit
HAMAPiMF_00199 ApaH, 1 hit
InterProiView protein in InterPro
IPR004617 ApaH
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
PfamiView protein in Pfam
PF00149 Metallophos, 1 hit
PIRSFiPIRSF000903 B5n-ttraPtase_sm, 1 hit
TIGRFAMsiTIGR00668 apaH, 1 hit

Sequencei

Sequence statusi: Complete.

Q4QMZ7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATYFVGDLQ GCYDELQLLL ERVNFNPTQD KLYLVGDLVA RGDKSLECLR
60 70 80 90 100
FVKSLGDSAQ TVLGNHDLHL IATALGIKKV KPRDRVDAIF NAPDFDELIH
110 120 130 140 150
WLRHQPLLVH NKKLNFLMVH AGISPDWNLE TAKSCAAEVE QILQNGDFHY
160 170 180 190 200
LIENMYSEQP DRWSPDLQGL ARHRYIINAF TRMRFCYLDH RLDFACKSPL
210 220 230 240 250
KYAPTELTPW FNLGNPLYKQ IPIVFGHWAS LVDEPTPKGV YALDTGCVWN
260 270
NRMTMLRWED KQIFTQSAVK NYSDF
Length:275
Mass (Da):31,792
Last modified:July 19, 2005 - v1
Checksum:i6DF8192F040A60E6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000057 Genomic DNA Translation: AAX87600.1
RefSeqiWP_005657958.1, NC_007146.2

Genome annotation databases

EnsemblBacteriaiAAX87600; AAX87600; NTHI0679
KEGGihit:NTHI0679

Similar proteinsi

Entry informationi

Entry nameiAPAH_HAEI8
AccessioniPrimary (citable) accession number: Q4QMZ7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 19, 2005
Last modified: March 28, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health