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Protein

Anaerobic glycerol-3-phosphate dehydrogenase subunit B

Gene

glpB

Organism
Haemophilus influenzae (strain 86-028NP)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor.UniRule annotation

Catalytic activityi

sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.UniRule annotation

Cofactori

FMNUniRule annotation

Pathwayi: glycerol degradation via glycerol kinase pathway

This protein is involved in step 1 of the subpathway that synthesizes glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Anaerobic glycerol-3-phosphate dehydrogenase subunit B (glpB)
This subpathway is part of the pathway glycerol degradation via glycerol kinase pathway, which is itself part of Polyol metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route), the pathway glycerol degradation via glycerol kinase pathway and in Polyol metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
LigandFlavoprotein, FMN

Enzyme and pathway databases

UniPathwayiUPA00618; UER00673

Names & Taxonomyi

Protein namesi
Recommended name:
Anaerobic glycerol-3-phosphate dehydrogenase subunit BUniRule annotation (EC:1.1.5.3UniRule annotation)
Short name:
Anaerobic G-3-P dehydrogenase subunit BUniRule annotation
Short name:
Anaerobic G3Pdhase BUniRule annotation
Gene namesi
Name:glpBUniRule annotation
Ordered Locus Names:NTHI0806
OrganismiHaemophilus influenzae (strain 86-028NP)
Taxonomic identifieri281310 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
Proteomesi
  • UP000002525 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002589021 – 432Anaerobic glycerol-3-phosphate dehydrogenase subunit BAdd BLAST432

Proteomic databases

PRIDEiQ4QMN2

Interactioni

Subunit structurei

Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ4QMN2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the anaerobic G-3-P dehydrogenase subunit B family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000278489
KOiK00112
OMAiVAINAQC
OrthoDBiPOG091H0GYK

Family and domain databases

Gene3Di3.50.50.60, 1 hit
HAMAPiMF_00753 Glycerol3P_GlpB, 1 hit
InterProiView protein in InterPro
IPR003953 FAD-binding_2
IPR036188 FAD/NAD-bd_sf
IPR009158 G3P_DH_GlpB_su
PfamiView protein in Pfam
PF00890 FAD_binding_2, 1 hit
PIRSFiPIRSF000141 Anaerobic_G3P_dh, 1 hit
SUPFAMiSSF51905 SSF51905, 4 hits
TIGRFAMsiTIGR03378 glycerol3P_GlpB, 1 hit

Sequencei

Sequence statusi: Complete.

Q4QMN2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNFDVAIIGG GLAGLTCGIA LQQCGKRCVI INNGQAAIDF ASGSLDLLSR
60 70 80 90 100
MPSTTYGENR AVENLKENIT ALRNELPAHP YSLLGAEKVL AKAQDFERLA
110 120 130 140 150
NELNLDLIGS TEKNHWRVTG LGSLRGAWLS PNSVPTVQGN EPFPHKRIAV
160 170 180 190 200
LGIEGYHDFQ PQLLAANLVL NPQFEHCEVT SGFLNIPQLD ELRKNAREFR
210 220 230 240 250
SVNISQLLEH KLAFNDLVKE IIESAQGAEA VFLPACFGLE NQEFMTALRD
260 270 280 290 300
ATKLALFELP TLPPSLLGMR QRIQLRHKFE SLGGLMINGD SALNATFEGN
310 320 330 340 350
KVRCINTRLL ENEEITADNF VLASGSFFSK GLISEFDKIY EPVFESDIIG
360 370 380 390 400
VEGFNQKDRF TWTVHRFAHP QPYQSAGVAI NAQCQVQKCG QFLTNLYAVG
410 420 430
NVIGGFNALE LGCGSGVAVV TALAVADEIL AK
Length:432
Mass (Da):47,188
Last modified:July 19, 2005 - v1
Checksum:iFDE26E22AA4AD91C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000057 Genomic DNA Translation: AAX87715.1
RefSeqiWP_011272168.1, NC_007146.2

Genome annotation databases

EnsemblBacteriaiAAX87715; AAX87715; NTHI0806
KEGGihit:NTHI0806

Similar proteinsi

Entry informationi

Entry nameiGLPB_HAEI8
AccessioniPrimary (citable) accession number: Q4QMN2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: July 19, 2005
Last modified: May 23, 2018
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health