Reviewed, UniProtKB/Swiss-Prot Q4QMN2 (GLPB_HAEI8)

Names and origin

Protein names

Recommended name:
    Anaerobic glycerol-3-phosphate dehydrogenase subunit B
      Short name=Anaerobic G-3-P dehydrogenase subunit B
      Short name=Anaerobic G3Pdhase B
    EC=1.1.5.3

Gene names

Name:	glpB
Ordered Locus Names:	NTHI0806

Organism

Haemophilus influenzae (strain 86-028NP) [Complete proteome] [HAMAP]

Taxonomic identifier

281310 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus

Protein attributes

Sequence length	432 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor By similarity.
Catalytic activity	sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol. HAMAP MF_00753
Cofactor	FMN By similarity.
Pathway	Polyol metabolism; glycerol degradation via glycerol kinase pathway; glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route): step 1/1. HAMAP MF_00753
Subunit structure	Composed of a catalytic glpA/B dimer and of membrane bound glpC By similarity.
Sequence similarities	Belongs to the anaerobic G-3-P dehydrogenase subunit B family.

Ontologies

Keywords
Ligand	FMN Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	electron carrier activity Inferred from electronic annotation. Source: InterPro glycerol-3-phosphate dehydrogenase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 432	432	Anaerobic glycerol-3-phosphate dehydrogenase subunit B HAMAP MF_00753		PRO_0000258902

Sequences

	Sequence		Length	Mass (Da)
	Q4QMN2-1 [UniParc]. Last modified July 19, 2005. Version 1. Checksum: FDE26E22AA4AD91C	FASTA	432	47,188
	10 20 30 40 50 60 MNFDVAIIGG GLAGLTCGIA LQQCGKRCVI INNGQAAIDF ASGSLDLLSR MPSTTYGENR 70 80 90 100 110 120 AVENLKENIT ALRNELPAHP YSLLGAEKVL AKAQDFERLA NELNLDLIGS TEKNHWRVTG 130 140 150 160 170 180 LGSLRGAWLS PNSVPTVQGN EPFPHKRIAV LGIEGYHDFQ PQLLAANLVL NPQFEHCEVT 190 200 210 220 230 240 SGFLNIPQLD ELRKNAREFR SVNISQLLEH KLAFNDLVKE IIESAQGAEA VFLPACFGLE 250 260 270 280 290 300 NQEFMTALRD ATKLALFELP TLPPSLLGMR QRIQLRHKFE SLGGLMINGD SALNATFEGN 310 320 330 340 350 360 KVRCINTRLL ENEEITADNF VLASGSFFSK GLISEFDKIY EPVFESDIIG VEGFNQKDRF 370 380 390 400 410 420 TWTVHRFAHP QPYQSAGVAI NAQCQVQKCG QFLTNLYAVG NVIGGFNALE LGCGSGVAVV 430 TALAVADEIL AK

References

[1]

"Genomic sequence of an otitis media isolate of nontypeable Haemophilus influenzae: comparative study with H. influenzae serotype d, strain KW20." Harrison A., Dyer D.W., Gillaspy A., Ray W.C., Mungur R., Carson M.B., Zhong H., Gipson J., Gipson M., Johnson L.S., Lewis L., Bakaletz L.O., Munson R.S. Jr. J. Bacteriol. 187:4627-4636(2005) [PubMed: 15968074] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000057 Genomic DNA. Translation: AAX87715.1.
RefSeq	YP_248375.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3430116.
GenomeReviews	Gene locus NTHI0806 in contig CP000057_GR.
KEGG	hit:NTHI0806.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q4QMN2.
OMA	Q4QMN2. TWLSQPF.
Enzyme and pathway databases
BioCyc	HINF281310:NTHI0806-MON.
Family and domain databases
HAMAP	MF_00753. [Tree]
InterPro	IPR009158. Anaerobic_glycerol3P_DH_bsu. IPR003953. FAD_bind2_N. [Graphical view]
Pfam	PF00890. FAD_binding_2. 1 hit. [Graphical view]
PIRSF	PIRSF000141. Anaerobic_G3P_dh. 1 hit.
TIGRFAMs	TIGR03378. glycerol3P_GlpB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLPB_HAEI8

Accession

Primary (citable) accession number: Q4QMN2

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 31, 2006
Last sequence update:	July 19, 2005
Last modified:	June 16, 2009
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)