ID   PCKA_HAEI8              Reviewed;         538 AA.
AC   Q4QM91;
DT   30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   16-JUN-2009, entry version 22.
DE   RecName: Full=Phosphoenolpyruvate carboxykinase [ATP];
DE            Short=PEP carboxykinase;
DE            Short=PEPCK;
DE            EC=4.1.1.49;
DE   AltName: Full=Phosphoenolpyruvate carboxylase;
GN   Name=pckA; OrderedLocusNames=NTHI0973;
OS   Haemophilus influenzae (strain 86-028NP).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=281310;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15968074; DOI=10.1128/JB.187.13.4627-4636.2005;
RA   Harrison A., Dyer D.W., Gillaspy A., Ray W.C., Mungur R., Carson M.B.,
RA   Zhong H., Gipson J., Gipson M., Johnson L.S., Lewis L., Bakaletz L.O.,
RA   Munson R.S. Jr.;
RT   "Genomic sequence of an otitis media isolate of nontypeable
RT   Haemophilus influenzae: comparative study with H. influenzae serotype
RT   d, strain KW20.";
RL   J. Bacteriol. 187:4627-4636(2005).
CC   -!- CATALYTIC ACTIVITY: ATP + oxaloacetate = ADP + phosphoenolpyruvate
CC       + CO(2).
CC   -!- PATHWAY: Carbohydrate biosynthesis; gluconeogenesis.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the phosphoenolpyruvate carboxykinase [ATP]
CC       family.
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DR   EMBL; CP000057; AAX87856.1; -; Genomic_DNA.
DR   RefSeq; YP_248516.1; -.
DR   SMR; Q4QM91; 3-537.
DR   GeneID; 3430279; -.
DR   GenomeReviews; CP000057_GR; NTHI0973.
DR   KEGG; hit:NTHI0973; -.
DR   HOGENOM; Q4QM91; -.
DR   OMA; Q4QM91; MFIRPTE.
DR   BioCyc; HINF281310:NTHI0973-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR   GO; GO:0004612; F:phosphoenolpyruvate carboxykinase (ATP) act...; IEA:HAMAP.
DR   GO; GO:0006094; P:gluconeogenesis; IEA:HAMAP.
DR   HAMAP; MF_00453; -; 1.
DR   InterPro; IPR001272; PEP_carboxykinase_ATP.
DR   InterPro; IPR013035; PEP_carboxykinase_C.
DR   InterPro; IPR008210; PEP_carboxykinase_N.
DR   InterPro; IPR015994; PEPCK_ATP_CS.
DR   Gene3D; G3DSA:3.90.228.20; PEP_carboxykinase_C; 1.
DR   Gene3D; G3DSA:3.40.449.10; PEP_carboxykinase_N; 1.
DR   Pfam; PF01293; PEPCK_ATP; 1.
DR   PIRSF; PIRSF006294; PEP_crbxkin; 1.
DR   ProDom; PD004738; PEPCK_N; 1.
DR   TIGRFAMs; TIGR00224; pckA; 1.
DR   PROSITE; PS00532; PEPCK_ATP; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; Decarboxylase;
KW   Gluconeogenesis; Lyase; Nucleotide-binding.
FT   CHAIN         1    538       Phosphoenolpyruvate carboxykinase [ATP].
FT                                /FTId=PRO_0000236925.
FT   NP_BIND     246    253       ATP (By similarity).
SQ   SEQUENCE   538 AA;  59445 MW;  FC15EC63F24D1E1D CRC64;
     MTDLNKVVKE LEALGIYDVK EVVYNPSYEQ LFEEETKPGL EGFEKGTLTT TGAVAVDTGI
     FTGRSPKDKY IVLDEKTKDT VWWTSETAKN DNKPMNQATW QSLKDLVTNQ LSRKRLFVVD
     GFCGASEHDR IAVRIVTEVA WQAHFVKNMF IRPTEEQLKN FEPDFVVMNG SKVTNPNWKE
     QGLNSENFVA FNLTERIQLI GGTWYGGEMK KGMFSMMNYF LPLKGVGAMH CSANVGKDGD
     VAIFFGLSGT GKTTLSTDPK RELIGDDEHG WDDVGIFNFE GGCYAKTIHL SEENEPDIYH
     AIRRDALLEN VVVRSDGSVD FDDGSKTENT RVSYPIYHID NIVKPVSRAG HATKVIFLTA
     DAFGVLPPVS KLTPEQTKYY FLSGFTAKLA GTERGITEPT PTFSACFGAA FLTLHPTQYA
     EVLVKRMQAA GAEAYLVNTG WNGTGKRISI KDTRGIIDAI LDGSIEKAEM GELPIFNLAI
     PKALPGVDSA ILDPRDTYAD KAQWQSKAED LAGRFVKNFV KYATNEEGKA LIAAGPKA
//