ID   SYGA_HAEI8              Reviewed;         302 AA.
AC   Q4QLY1;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   16-JUN-2009, entry version 22.
DE   RecName: Full=Glycyl-tRNA synthetase alpha subunit;
DE            EC=6.1.1.14;
DE   AltName: Full=Glycine--tRNA ligase alpha subunit;
DE            Short=GlyRS;
GN   Name=glyQ; OrderedLocusNames=NTHI1098;
OS   Haemophilus influenzae (strain 86-028NP).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=281310;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15968074; DOI=10.1128/JB.187.13.4627-4636.2005;
RA   Harrison A., Dyer D.W., Gillaspy A., Ray W.C., Mungur R., Carson M.B.,
RA   Zhong H., Gipson J., Gipson M., Johnson L.S., Lewis L., Bakaletz L.O.,
RA   Munson R.S. Jr.;
RT   "Genomic sequence of an otitis media isolate of nontypeable
RT   Haemophilus influenzae: comparative study with H. influenzae serotype
RT   d, strain KW20.";
RL   J. Bacteriol. 187:4627-4636(2005).
CC   -!- CATALYTIC ACTIVITY: ATP + glycine + tRNA(Gly) = AMP + diphosphate
CC       + glycyl-tRNA(Gly).
CC   -!- SUBUNIT: Tetramer of two alpha and two beta subunits (By
CC       similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase
CC       family.
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DR   EMBL; CP000057; AAX87966.1; -; Genomic_DNA.
DR   RefSeq; YP_248626.1; -.
DR   GeneID; 3430391; -.
DR   GenomeReviews; CP000057_GR; NTHI1098.
DR   KEGG; hit:NTHI1098; -.
DR   HOGENOM; Q4QLY1; -.
DR   OMA; Q4QLY1; CRRPTDG.
DR   BioCyc; HINF281310:NTHI1098-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR   GO; GO:0004820; F:glycine-tRNA ligase activity; IEA:HAMAP.
DR   GO; GO:0006426; P:glycyl-tRNA aminoacylation; IEA:HAMAP.
DR   HAMAP; MF_00254; -; 1.
DR   InterPro; IPR006194; Gly-tRNA-synth_II_heterodimer.
DR   InterPro; IPR002310; Gly-tRNA_synth_IIc_asu.
DR   Pfam; PF02091; tRNA-synt_2e; 1.
DR   PRINTS; PR01044; TRNASYNTHGA.
DR   ProDom; PD006985; tRNA_synt_2e; 1.
DR   TIGRFAMs; TIGR00388; glyQ; 1.
DR   PROSITE; PS50861; AA_TRNA_LIGASE_II_GLYAB; 1.
PE   3: Inferred from homology;
KW   Aminoacyl-tRNA synthetase; ATP-binding; Complete proteome; Cytoplasm;
KW   Ligase; Nucleotide-binding; Protein biosynthesis.
FT   CHAIN         1    302       Glycyl-tRNA synthetase alpha subunit.
FT                                /FTId=PRO_1000047427.
SQ   SEQUENCE   302 AA;  34471 MW;  9FCD91C52A926ABB CRC64;
     MSTKFNVKTF QGMILALQEY WANQGCTIVQ PFDMEVGAGT SHPMTALRAL GPEPMAFAYV
     QPSRRPTDGR YGENPNRLQH YYQFQVVIKP SPDNIQELYL GSLEMLGFDP TQNDIRFVED
     NWENPTLGAW GLGWEVWLNG MEVTQFTYFQ QVGGLECKPV TGEVTYGLER LAMYIQGVDS
     VYDLVWSDGP LGKTTYGDVF HQNEVEQSTY NFEHANTDFL FYCFDQYEKE AQELLALEKP
     LPLPAYERIL KAAHSFNLLD ARKAISVTER QRYILRIRAL TKGVAEAYYA SREALGFPGC
     KK
//