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Q4QL71

- CAPP_HAEI8

UniProt

Q4QL71 - CAPP_HAEI8

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Protein
Phosphoenolpyruvate carboxylase
Gene
ppc, NTHI1403
Organism
Haemophilus influenzae (strain 86-028NP)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Magnesium By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381 By similarity
Active sitei545 – 5451 By similarity

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Carbon dioxide fixation

Keywords - Ligandi

Magnesium

Enzyme and pathway databases

BioCyciHINF281310:GJ89-1307-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylase (EC:4.1.1.31)
Short name:
PEPC
Short name:
PEPCase
Gene namesi
Name:ppc
Ordered Locus Names:NTHI1403
OrganismiHaemophilus influenzae (strain 86-028NP)
Taxonomic identifieri281310 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
ProteomesiUP000002525: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 879879Phosphoenolpyruvate carboxylaseUniRule annotation
PRO_1000025559Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi281310.NTHI1403.

Structurei

3D structure databases

ProteinModelPortaliQ4QL71.
SMRiQ4QL71. Positions 4-879.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238648.
KOiK01595.
OMAiELSTISC.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4QL71-1 [UniParc]FASTAAdd to Basket

« Hide

MTQEYSTLRN NISMLGRFLG ETINDAQGED ILELIENIRK LSRNSRAGDD    50
KARQALLDTL GSISNENIIP VARAFSQFLN LTNIAEQYQT ISREHSLAQS 100
SSQSLSELFK RLKEQNASVE EVHKTVEKLL IELVLTAHPT ETTRRSLIHK 150
HIEINKCLSK LEHHDLTEKE RNIIERLLLR LIAEAWHTNE IRTVRPTPFD 200
EAKWGFAMLE NSLWQAVPEF LRQLNETARE FLGYDLPVGL KPVRISSWMG 250
GDRDGNPFVT AQITKKVLYF ARWKAADLFL QDISKLADEL SMMKCSDEFR 300
DKYGEHLEPY RFVVKNLRNQ LTATLAYFDD HLSNRTPRVS ESEIILEDNQ 350
LWEPLYDCYQ SLIQCGMRII ANGSLLDILH RISCFGVTLS QMDIRQESTR 400
HTDAIAEIMR YIGLGDYSQW MEDDKQAFLI RELSSRRPLI PQNWTPSPET 450
KEILDTCKVI AQQKQGVIAC YVISMARSAS DVLAVHLLLK EAGVPYHIPV 500
VPLFETLEDL DAAEKVMTQL FNVGWYRGVI NNRQMVMIGY SDSAKDAGMM 550
AASWAQYRAQ EALVNLTEKL GIELTLFHGR GGTIGRGGAP AHAALLSQPP 600
RSLKNGLRVT EQGEMIRFKL GLPAVAVETF DLYASAILEA NLLPPPEPKP 650
EWRTIMDELS TISCDIYRGV VRGDKDFVPY FRSATPEQEL SKLPLGSRPA 700
KRNPNGGVES LRAIPWIFAW MQNRLMLPAW LGAGAAIRQV IEQGKGDIIH 750
KMCENWPFFS TRIGMLEMVF SKSDTWLSQQ YDQRLVKKEL WYLGENLRKQ 800
LEDDIQTVLS LSHQSELMSD LPWIADSIAL RNIYTDPLNL LQVELLHRFR 850
ENPEQVNPDV EQALMITITG IAAGMRNTG 879
Length:879
Mass (Da):100,080
Last modified:July 19, 2005 - v1
Checksum:i475AB42457533410
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000057 Genomic DNA. Translation: AAX88226.1.
RefSeqiWP_011272456.1. NC_007146.2.
YP_248886.1. NC_007146.2.

Genome annotation databases

EnsemblBacteriaiAAX88226; AAX88226; NTHI1403.
GeneIDi3430655.
KEGGihit:NTHI1403.
PATRICi20182907. VBIHaeInf100748_1297.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000057 Genomic DNA. Translation: AAX88226.1 .
RefSeqi WP_011272456.1. NC_007146.2.
YP_248886.1. NC_007146.2.

3D structure databases

ProteinModelPortali Q4QL71.
SMRi Q4QL71. Positions 4-879.
ModBasei Search...

Protein-protein interaction databases

STRINGi 281310.NTHI1403.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAX88226 ; AAX88226 ; NTHI1403 .
GeneIDi 3430655.
KEGGi hit:NTHI1403.
PATRICi 20182907. VBIHaeInf100748_1297.

Phylogenomic databases

eggNOGi COG2352.
HOGENOMi HOG000238648.
KOi K01595.
OMAi ELSTISC.
OrthoDBi EOG6TJ7T8.

Enzyme and pathway databases

BioCyci HINF281310:GJ89-1307-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genomic sequence of an otitis media isolate of nontypeable Haemophilus influenzae: comparative study with H. influenzae serotype d, strain KW20."
    Harrison A., Dyer D.W., Gillaspy A., Ray W.C., Mungur R., Carson M.B., Zhong H., Gipson J., Gipson M., Johnson L.S., Lewis L., Bakaletz L.O., Munson R.S. Jr.
    J. Bacteriol. 187:4627-4636(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 86-028NP.

Entry informationi

Entry nameiCAPP_HAEI8
AccessioniPrimary (citable) accession number: Q4QL71
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 19, 2005
Last modified: September 3, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi