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Q4QL71

- CAPP_HAEI8

UniProt

Q4QL71 - CAPP_HAEI8

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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Haemophilus influenzae (strain 86-028NP)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Magnesium.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381UniRule annotation
Active sitei545 – 5451UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Carbon dioxide fixation

Keywords - Ligandi

Magnesium

Enzyme and pathway databases

BioCyciHINF281310:GJ89-1307-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:NTHI1403
OrganismiHaemophilus influenzae (strain 86-028NP)
Taxonomic identifieri281310 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
ProteomesiUP000002525: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 879879Phosphoenolpyruvate carboxylasePRO_1000025559Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi281310.NTHI1403.

Structurei

3D structure databases

ProteinModelPortaliQ4QL71.
SMRiQ4QL71. Positions 4-879.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238648.
KOiK01595.
OMAiELSTISC.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4QL71 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTQEYSTLRN NISMLGRFLG ETINDAQGED ILELIENIRK LSRNSRAGDD
60 70 80 90 100
KARQALLDTL GSISNENIIP VARAFSQFLN LTNIAEQYQT ISREHSLAQS
110 120 130 140 150
SSQSLSELFK RLKEQNASVE EVHKTVEKLL IELVLTAHPT ETTRRSLIHK
160 170 180 190 200
HIEINKCLSK LEHHDLTEKE RNIIERLLLR LIAEAWHTNE IRTVRPTPFD
210 220 230 240 250
EAKWGFAMLE NSLWQAVPEF LRQLNETARE FLGYDLPVGL KPVRISSWMG
260 270 280 290 300
GDRDGNPFVT AQITKKVLYF ARWKAADLFL QDISKLADEL SMMKCSDEFR
310 320 330 340 350
DKYGEHLEPY RFVVKNLRNQ LTATLAYFDD HLSNRTPRVS ESEIILEDNQ
360 370 380 390 400
LWEPLYDCYQ SLIQCGMRII ANGSLLDILH RISCFGVTLS QMDIRQESTR
410 420 430 440 450
HTDAIAEIMR YIGLGDYSQW MEDDKQAFLI RELSSRRPLI PQNWTPSPET
460 470 480 490 500
KEILDTCKVI AQQKQGVIAC YVISMARSAS DVLAVHLLLK EAGVPYHIPV
510 520 530 540 550
VPLFETLEDL DAAEKVMTQL FNVGWYRGVI NNRQMVMIGY SDSAKDAGMM
560 570 580 590 600
AASWAQYRAQ EALVNLTEKL GIELTLFHGR GGTIGRGGAP AHAALLSQPP
610 620 630 640 650
RSLKNGLRVT EQGEMIRFKL GLPAVAVETF DLYASAILEA NLLPPPEPKP
660 670 680 690 700
EWRTIMDELS TISCDIYRGV VRGDKDFVPY FRSATPEQEL SKLPLGSRPA
710 720 730 740 750
KRNPNGGVES LRAIPWIFAW MQNRLMLPAW LGAGAAIRQV IEQGKGDIIH
760 770 780 790 800
KMCENWPFFS TRIGMLEMVF SKSDTWLSQQ YDQRLVKKEL WYLGENLRKQ
810 820 830 840 850
LEDDIQTVLS LSHQSELMSD LPWIADSIAL RNIYTDPLNL LQVELLHRFR
860 870
ENPEQVNPDV EQALMITITG IAAGMRNTG
Length:879
Mass (Da):100,080
Last modified:July 19, 2005 - v1
Checksum:i475AB42457533410
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000057 Genomic DNA. Translation: AAX88226.1.
RefSeqiWP_011272456.1. NC_007146.2.
YP_248886.1. NC_007146.2.

Genome annotation databases

EnsemblBacteriaiAAX88226; AAX88226; NTHI1403.
GeneIDi3430655.
KEGGihit:NTHI1403.
PATRICi20182907. VBIHaeInf100748_1297.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000057 Genomic DNA. Translation: AAX88226.1 .
RefSeqi WP_011272456.1. NC_007146.2.
YP_248886.1. NC_007146.2.

3D structure databases

ProteinModelPortali Q4QL71.
SMRi Q4QL71. Positions 4-879.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 281310.NTHI1403.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAX88226 ; AAX88226 ; NTHI1403 .
GeneIDi 3430655.
KEGGi hit:NTHI1403.
PATRICi 20182907. VBIHaeInf100748_1297.

Phylogenomic databases

eggNOGi COG2352.
HOGENOMi HOG000238648.
KOi K01595.
OMAi ELSTISC.
OrthoDBi EOG6TJ7T8.

Enzyme and pathway databases

BioCyci HINF281310:GJ89-1307-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genomic sequence of an otitis media isolate of nontypeable Haemophilus influenzae: comparative study with H. influenzae serotype d, strain KW20."
    Harrison A., Dyer D.W., Gillaspy A., Ray W.C., Mungur R., Carson M.B., Zhong H., Gipson J., Gipson M., Johnson L.S., Lewis L., Bakaletz L.O., Munson R.S. Jr.
    J. Bacteriol. 187:4627-4636(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 86-028NP.

Entry informationi

Entry nameiCAPP_HAEI8
AccessioniPrimary (citable) accession number: Q4QL71
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 19, 2005
Last modified: October 1, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3