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Q4QL07

- G6PI_HAEI8

UniProt

Q4QL07 - G6PI_HAEI8

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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Haemophilus influenzae (strain 86-028NP)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei355 – 3551Proton donorUniRule annotation
Active sitei387 – 3871UniRule annotation
Active sitei515 – 5151UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciHINF281310:GJ89-1376-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:NTHI1475
OrganismiHaemophilus influenzae (strain 86-028NP)
Taxonomic identifieri281310 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
ProteomesiUP000002525: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 549549Glucose-6-phosphate isomerasePRO_0000180651Add
BLAST

Proteomic databases

PRIDEiQ4QL07.

Interactioni

Protein-protein interaction databases

STRINGi281310.NTHI1475.

Structurei

3D structure databases

ProteinModelPortaliQ4QL07.
SMRiQ4QL07. Positions 10-549.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4QL07-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKNINPTHTQ AWKSLEAHKA ELSNTTIQDL FKQEKNRFDD YSLTFNNQIL
60 70 80 90 100
VDFSKNNINQ TTLSHLRQLA QECALDSAKE AMFTGEKINR TENRAVLHTA
110 120 130 140 150
LRNRTNTPVL VDGKDVMPEV NAVLAKMKDF CQRIISGEWK GYTGKAITDV
160 170 180 190 200
VNIGIGGSDL GPYMVTEALR PYKNHLNMHF VSNVDGTHIA ETLKKVNPET
210 220 230 240 250
TLFLVASKTF TTQETMTNAQ SARDWLLKAA KDESAVAKHF AALSTNAKDV
260 270 280 290 300
EKFGIDTNNM FEFWDWVGGR YSLWSAIGLS IALSIGFENF EALLNGAHEM
310 320 330 340 350
DKHFRTTPIE KNIPTTLALV GLWNTNFLGA QTEAILPYDQ YLHRFAAYFQ
360 370 380 390 400
QGNMESNGKY VDRDGNVINN YQTGPIIWGE PGTNGQHAFY QLIHQGTTLI
410 420 430 440 450
PCDFIAPAQS HNPLADHHNK LLSNFFAQTE ALAFGKTKEE VEAEFVKAGK
460 470 480 490 500
SLDDVKNIVP FKVFTGNKPT NSILVQKITP FTLGALIAMY EHKIFVQGVI
510 520 530 540
FNIFSFDQWG VELGKQLANR ILPELTDSEK VASHDSSTNG LINQFKAWR
Length:549
Mass (Da):61,561
Last modified:November 8, 2005 - v2
Checksum:iB57659BE25B9706F
GO

Sequence cautioni

The sequence AAX88290.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000057 Genomic DNA. Translation: AAX88290.1. Different initiation.
RefSeqiYP_248950.2. NC_007146.2.

Genome annotation databases

EnsemblBacteriaiAAX88290; AAX88290; NTHI1475.
GeneIDi3430724.
KEGGihit:NTHI1475.
PATRICi20183047. VBIHaeInf100748_1363.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000057 Genomic DNA. Translation: AAX88290.1 . Different initiation.
RefSeqi YP_248950.2. NC_007146.2.

3D structure databases

ProteinModelPortali Q4QL07.
SMRi Q4QL07. Positions 10-549.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 281310.NTHI1475.

Proteomic databases

PRIDEi Q4QL07.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAX88290 ; AAX88290 ; NTHI1475 .
GeneIDi 3430724.
KEGGi hit:NTHI1475.
PATRICi 20183047. VBIHaeInf100748_1363.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000261370.
KOi K01810.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
BioCyci HINF281310:GJ89-1376-MONOMER.

Family and domain databases

Gene3Di 1.10.1390.10. 1 hit.
HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genomic sequence of an otitis media isolate of nontypeable Haemophilus influenzae: comparative study with H. influenzae serotype d, strain KW20."
    Harrison A., Dyer D.W., Gillaspy A., Ray W.C., Mungur R., Carson M.B., Zhong H., Gipson J., Gipson M., Johnson L.S., Lewis L., Bakaletz L.O., Munson R.S. Jr.
    J. Bacteriol. 187:4627-4636(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 86-028NP.

Entry informationi

Entry nameiG6PI_HAEI8
AccessioniPrimary (citable) accession number: Q4QL07
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: November 8, 2005
Last modified: October 29, 2014
This is version 55 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3