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Protein

Glycogen synthase

Gene

glgA

Organism
Haemophilus influenzae (strain 86-028NP)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Synthesizes alpha-1,4-glucan chains using ADP-glucose.UniRule annotation

Catalytic activityi

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1).UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei15 – 151ADP-glucoseUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Glycogen biosynthesis

Enzyme and pathway databases

BioCyciHINF281310:GJ89-1671-MONOMER.
UniPathwayiUPA00164.

Protein family/group databases

CAZyiGT5. Glycosyltransferase Family 5.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycogen synthaseUniRule annotation (EC:2.4.1.21UniRule annotation)
Alternative name(s):
Starch [bacterial glycogen] synthaseUniRule annotation
Gene namesi
Name:glgAUniRule annotation
Ordered Locus Names:NTHI1806
OrganismiHaemophilus influenzae (strain 86-028NP)
Taxonomic identifieri281310 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
ProteomesiUP000002525 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 476476Glycogen synthasePRO_0000230243Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi281310.NTHI1806.

Structurei

3D structure databases

ProteinModelPortaliQ4QK70.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0297.
HOGENOMiHOG000294941.
KOiK00703.
OMAiLTCAYLE.
OrthoDBiEOG6JTC6Z.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q4QK70-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKILHVCSEL YPLLKTGGLA DVLGALPQAQ NQIGLDARVL LPAYPAIIAG
60 70 80 90 100
IQNTQVVAEF DNFAGHVVLR YGEYNGVGIY LIDAPHLYGR EGNPYHDAYY
110 120 130 140 150
NDYGDNYKRF ALLGWVGAEL ATGLDSWWRA EVVHAHDWHA GLCAAYLFNK
160 170 180 190 200
GRPAKSVFTI HNLAYQGQFS YHHLYEIGLP TGMFHVEGLE LFGQISYLKS
210 220 230 240 250
GLFYSDASTA VSPTYAEEIT TPEFAYGLQG LLSGLKAQGR LVGILNGVDE
260 270 280 290 300
NIWHPNVDQY IPHHYKLKYM AGKKKNKAEL QAYFNLPQDE SALAFVMVTR
310 320 330 340 350
LTEQKGVDLL IESADEIVKQ GGQLMILGSG APHFEQGIRE LAERYPQNIA
360 370 380 390 400
VKIGYDEALS HLMVAGGDVI LVPSRFEPCG LTQLYGLQYG TLPLVRKTGG
410 420 430 440 450
LADTVVDSTS ESIKARTATG FVFESATPEA LRHCLQRAFA LWQKPRAWAM
460 470
VRTDAMEQDF SWRKAAEQYR TLYERL
Length:476
Mass (Da):52,975
Last modified:July 19, 2005 - v1
Checksum:i68589161C0974443
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000057 Genomic DNA. Translation: AAX88577.1.
RefSeqiWP_005656779.1. NC_007146.2.
YP_249237.1. NC_007146.2.

Genome annotation databases

EnsemblBacteriaiAAX88577; AAX88577; NTHI1806.
KEGGihit:NTHI1806.
PATRICi20183664. VBIHaeInf100748_1669.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000057 Genomic DNA. Translation: AAX88577.1.
RefSeqiWP_005656779.1. NC_007146.2.
YP_249237.1. NC_007146.2.

3D structure databases

ProteinModelPortaliQ4QK70.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi281310.NTHI1806.

Protein family/group databases

CAZyiGT5. Glycosyltransferase Family 5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAX88577; AAX88577; NTHI1806.
KEGGihit:NTHI1806.
PATRICi20183664. VBIHaeInf100748_1669.

Phylogenomic databases

eggNOGiCOG0297.
HOGENOMiHOG000294941.
KOiK00703.
OMAiLTCAYLE.
OrthoDBiEOG6JTC6Z.

Enzyme and pathway databases

UniPathwayiUPA00164.
BioCyciHINF281310:GJ89-1671-MONOMER.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Genomic sequence of an otitis media isolate of nontypeable Haemophilus influenzae: comparative study with H. influenzae serotype d, strain KW20."
    Harrison A., Dyer D.W., Gillaspy A., Ray W.C., Mungur R., Carson M.B., Zhong H., Gipson J., Gipson M., Johnson L.S., Lewis L., Bakaletz L.O., Munson R.S. Jr.
    J. Bacteriol. 187:4627-4636(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 86-028NP.

Entry informationi

Entry nameiGLGA_HAEI8
AccessioniPrimary (citable) accession number: Q4QK70
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: July 19, 2005
Last modified: April 1, 2015
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.