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Q4QK70 (GLGA_HAEI8) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glycogen synthase

EC=2.4.1.21
Alternative name(s):
Starch [bacterial glycogen] synthase
Gene names
Name:glgA
Ordered Locus Names:NTHI1806
OrganismHaemophilus influenzae (strain 86-028NP) [Complete proteome] [HAMAP]
Taxonomic identifier281310 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus

Protein attributes

Sequence length476 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Synthesizes alpha-1,4-glucan chains using ADP-glucose By similarity. HAMAP-Rule MF_00484

Catalytic activity

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1). HAMAP-Rule MF_00484

Pathway

Glycan biosynthesis; glycogen biosynthesis. HAMAP-Rule MF_00484

Sequence similarities

Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.

Ontologies

Keywords
   Biological processGlycogen biosynthesis
   Molecular functionGlycosyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycogen biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionstarch synthase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 476476Glycogen synthase HAMAP-Rule MF_00484
PRO_0000230243

Sites

Binding site151ADP-glucose By similarity

Sequences

Sequence LengthMass (Da)Tools
Q4QK70 [UniParc].

Last modified July 19, 2005. Version 1.
Checksum: 68589161C0974443

FASTA47652,975
        10         20         30         40         50         60 
MKILHVCSEL YPLLKTGGLA DVLGALPQAQ NQIGLDARVL LPAYPAIIAG IQNTQVVAEF 

        70         80         90        100        110        120 
DNFAGHVVLR YGEYNGVGIY LIDAPHLYGR EGNPYHDAYY NDYGDNYKRF ALLGWVGAEL 

       130        140        150        160        170        180 
ATGLDSWWRA EVVHAHDWHA GLCAAYLFNK GRPAKSVFTI HNLAYQGQFS YHHLYEIGLP 

       190        200        210        220        230        240 
TGMFHVEGLE LFGQISYLKS GLFYSDASTA VSPTYAEEIT TPEFAYGLQG LLSGLKAQGR 

       250        260        270        280        290        300 
LVGILNGVDE NIWHPNVDQY IPHHYKLKYM AGKKKNKAEL QAYFNLPQDE SALAFVMVTR 

       310        320        330        340        350        360 
LTEQKGVDLL IESADEIVKQ GGQLMILGSG APHFEQGIRE LAERYPQNIA VKIGYDEALS 

       370        380        390        400        410        420 
HLMVAGGDVI LVPSRFEPCG LTQLYGLQYG TLPLVRKTGG LADTVVDSTS ESIKARTATG 

       430        440        450        460        470 
FVFESATPEA LRHCLQRAFA LWQKPRAWAM VRTDAMEQDF SWRKAAEQYR TLYERL 

« Hide

References

[1]"Genomic sequence of an otitis media isolate of nontypeable Haemophilus influenzae: comparative study with H. influenzae serotype d, strain KW20."
Harrison A., Dyer D.W., Gillaspy A., Ray W.C., Mungur R., Carson M.B., Zhong H., Gipson J., Gipson M., Johnson L.S., Lewis L., Bakaletz L.O., Munson R.S. Jr.
J. Bacteriol. 187:4627-4636(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 86-028NP.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000057 Genomic DNA. Translation: AAX88577.1.
RefSeqYP_249237.1. NC_007146.2.

3D structure databases

ProteinModelPortalQ4QK70.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING281310.NTHI1806.

Protein family/group databases

CAZyGT5. Glycosyltransferase Family 5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAX88577; AAX88577; NTHI1806.
GeneID3431019.
KEGGhit:NTHI1806.
PATRIC20183664. VBIHaeInf100748_1669.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0297.
HOGENOMHOG000294941.
KOK00703.
OMAPYHDESQ.
OrthoDBEOG6JTC6Z.

Enzyme and pathway databases

BioCycHINF281310:GJ89-1671-MONOMER.
UniPathwayUPA00164.

Family and domain databases

HAMAPMF_00484. Glycogen_synth.
InterProIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsTIGR02095. glgA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLGA_HAEI8
AccessionPrimary (citable) accession number: Q4QK70
Entry history
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: July 19, 2005
Last modified: May 14, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways