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Protein
Submitted name:

2-oxoglutarate dehydrogenase E1 component

Gene

sucA

Organism
Haemophilus influenzae (strain 86-028NP)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. oxoglutarate dehydrogenase (succinyl-transferring) activity Source: UniProtKB-EC
  2. thiamine pyrophosphate binding Source: InterPro

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Enzyme and pathway databases

BioCyciHINF281310:GJ89-1812-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
2-oxoglutarate dehydrogenase E1 componentImported (EC:1.2.4.2Imported)
Gene namesi
Name:sucAImported
Ordered Locus Names:NTHI1964Imported
OrganismiHaemophilus influenzae (strain 86-028NP)Imported
Taxonomic identifieri281310 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
ProteomesiUP000002525 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi281310.NTHI1964.

Structurei

3D structure databases

ProteinModelPortaliQ4QJT1.
SMRiQ4QJT1. Positions 103-949.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0567.
HOGENOMiHOG000259588.
KOiK00164.
OMAiQNQGAWF.
OrthoDBiEOG6V1M1F.

Family and domain databases

Gene3Di3.40.50.970. 2 hits.
InterProiIPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.

Sequencei

Sequence statusi: Complete.

Q4QJT1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MERKYCFKYH NKEVIMQQNK AFDDWLASTA LGGANQSYIE ELYESYLSDP
60 70 80 90 100
QSVEESWRKT FDSLPKTTAL EQPHTPVRDY FRRLARENHN EAVTVIDPAA
110 120 130 140 150
GAKLVKVLQF INAYRFRGHL EANLDPLNYY RWKVSSVPEL DYRHHGFTEQ
160 170 180 190 200
DLNETFNINH YVYKRDTIKL GELAQMLKET YCGSIGLEFM HVQDMEQKMW
210 220 230 240 250
LQSKMESLLD KPLFTSEERV NFLRELTAAD GLERYLGAKF PGAKRFSLEG
260 270 280 290 300
SDAFIPLMKE IIRHSSRQGV NDVVMGMAHR GRLNMLVNVL GKKPENLFDE
310 320 330 340 350
FAGKHSSERT GDVKYHQGFS SDFAVDDKRV HLTLAFNPSH LEIVSPVVIG
360 370 380 390 400
SVRSRQTRMN DTEHSKVLAI TVHGDSAVAG QGVVQETLNM SNARGYSVGG
410 420 430 440 450
TIRIVINNQI GFTTSNPNDT RSTEYCTDIA KMIQAPIIHV NGDDPEAVAF
460 470 480 490 500
TARMAVEYRN LFKRDIFIDL ISYRRHGHNE ADEPLATQPM MYSIIKKHPT
510 520 530 540 550
PRKVYADRLV SEGVMTEEQV TEMANDYRDA LDNGDRVVSE WREMDTAKMD
560 570 580 590 600
WLQYLNYDWT APYESKFSQE RFLTLAKRVC EYPESLRAHP RVEKIYNDRK
610 620 630 640 650
AMYQGEKLLD WGMAETMAYA TLLDEGVNVR LSGEDAGRGT FFHRHAVVHN
660 670 680 690 700
QNDGTGYVPL THLHANQGRF EVWDSVLSEE SVLAFEYGYA TTDPKTLTIW
710 720 730 740 750
EAQFGDFANG AQIVIDQFIS SGEQKWGRMC GLVMLLPHGY EGQGPEHSSA
760 770 780 790 800
RLERYLQLCA EQNMQVCVPS TPAQVYHMLR RQSLRKMRRP LIAISPKSLL
810 820 830 840 850
RHPLAVSSLD ELINGTFQTV IGEIDELDPK DVKRVVMCSG KVYYDVLEQR
860 870 880 890 900
RANNQKDVAI IRIEQLYPFP HEDVKKALEP YAHVTDYVWC QEEPLNQGAW
910 920 930 940 950
YCSKHNFESA IPESVKLKYA GRPASASPAV GYMSLHTKQQ KQLVEDALSF
Length:950
Mass (Da):108,702
Last modified:July 18, 2005 - v1
Checksum:i932B796ACADED75A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000057 Genomic DNA. Translation: AAX88716.1.
RefSeqiWP_011272726.1. NC_007146.2.
YP_249376.1. NC_007146.2.

Genome annotation databases

EnsemblBacteriaiAAX88716; AAX88716; NTHI1964.
KEGGihit:NTHI1964.
PATRICi20183948. VBIHaeInf100748_1809.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000057 Genomic DNA. Translation: AAX88716.1.
RefSeqiWP_011272726.1. NC_007146.2.
YP_249376.1. NC_007146.2.

3D structure databases

ProteinModelPortaliQ4QJT1.
SMRiQ4QJT1. Positions 103-949.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi281310.NTHI1964.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAX88716; AAX88716; NTHI1964.
KEGGihit:NTHI1964.
PATRICi20183948. VBIHaeInf100748_1809.

Phylogenomic databases

eggNOGiCOG0567.
HOGENOMiHOG000259588.
KOiK00164.
OMAiQNQGAWF.
OrthoDBiEOG6V1M1F.

Enzyme and pathway databases

BioCyciHINF281310:GJ89-1812-MONOMER.

Family and domain databases

Gene3Di3.40.50.970. 2 hits.
InterProiIPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Genomic sequence of an otitis media isolate of nontypeable Haemophilus influenzae: comparative study with H. influenzae serotype d, strain KW20."
    Harrison A., Dyer D.W., Gillaspy A., Ray W.C., Mungur R., Carson M.B., Zhong H., Gipson J., Gipson M., Johnson L.S., Lewis L., Bakaletz L.O., Munson R.S. Jr.
    J. Bacteriol. 187:4627-4636(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 86-028NPImported.

Entry informationi

Entry nameiQ4QJT1_HAEI8
AccessioniPrimary (citable) accession number: Q4QJT1
Entry historyi
Integrated into UniProtKB/TrEMBL: July 18, 2005
Last sequence update: July 18, 2005
Last modified: March 31, 2015
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.